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Upregulation of miR-196a and HOTAIR drive malignant character in gastrointestinal stromal tumors.
Niinuma T, Suzuki H, Nojima M, Nosho K, Yamamoto H, Takamaru H, Yamamoto E, Maruyama R, Nobuoka T, Miyazaki Y, Nishida T, Bamba T, Kanda T, Ajioka Y, Taguchi T, Okahara S, Takahashi H, Nishida Y, Hosokawa M, Hasegawa T, Tokino T, Hirata K, Imai K, Toyota M, Shinomura Y. Niinuma T, et al. Among authors: hirata k. Cancer Res. 2012 Mar 1;72(5):1126-36. doi: 10.1158/0008-5472.CAN-11-1803. Epub 2012 Jan 18. Cancer Res. 2012. PMID: 22258453
Gene amplification and overexpression of PRDM14 in breast cancers.
Nishikawa N, Toyota M, Suzuki H, Honma T, Fujikane T, Ohmura T, Nishidate T, Ohe-Toyota M, Maruyama R, Sonoda T, Sasaki Y, Urano T, Imai K, Hirata K, Tokino T. Nishikawa N, et al. Among authors: hirata k. Cancer Res. 2007 Oct 15;67(20):9649-57. doi: 10.1158/0008-5472.CAN-06-4111. Cancer Res. 2007. PMID: 17942894
A novel correlation between LINE-1 hypomethylation and the malignancy of gastrointestinal stromal tumors.
Igarashi S, Suzuki H, Niinuma T, Shimizu H, Nojima M, Iwaki H, Nobuoka T, Nishida T, Miyazaki Y, Takamaru H, Yamamoto E, Yamamoto H, Tokino T, Hasegawa T, Hirata K, Imai K, Toyota M, Shinomura Y. Igarashi S, et al. Among authors: hirata k. Clin Cancer Res. 2010 Nov 1;16(21):5114-23. doi: 10.1158/1078-0432.CCR-10-0581. Epub 2010 Oct 26. Clin Cancer Res. 2010. PMID: 20978145
A Screen for Epigenetically Silenced microRNA Genes in Gastrointestinal Stromal Tumors.
Isosaka M, Niinuma T, Nojima M, Kai M, Yamamoto E, Maruyama R, Nobuoka T, Nishida T, Kanda T, Taguchi T, Hasegawa T, Tokino T, Hirata K, Suzuki H, Shinomura Y. Isosaka M, et al. Among authors: hirata k. PLoS One. 2015 Jul 27;10(7):e0133754. doi: 10.1371/journal.pone.0133754. eCollection 2015. PLoS One. 2015. PMID: 26214687 Free PMC article.
Cytoplasmic RASSF2A is a proapoptotic mediator whose expression is epigenetically silenced in gastric cancer.
Maruyama R, Akino K, Toyota M, Suzuki H, Imai T, Ohe-Toyota M, Yamamoto E, Nojima M, Fujikane T, Sasaki Y, Yamashita T, Watanabe Y, Hiratsuka H, Hirata K, Itoh F, Imai K, Shinomura Y, Tokino T. Maruyama R, et al. Among authors: hirata k. Carcinogenesis. 2008 Jul;29(7):1312-8. doi: 10.1093/carcin/bgn060. Epub 2008 Feb 29. Carcinogenesis. 2008. PMID: 18310659 Free PMC article.
Genomic screening for genes upregulated by demethylation revealed novel targets of epigenetic silencing in breast cancer.
Fujikane T, Nishikawa N, Toyota M, Suzuki H, Nojima M, Maruyama R, Ashida M, Ohe-Toyota M, Kai M, Nishidate T, Sasaki Y, Ohmura T, Hirata K, Tokino T. Fujikane T, et al. Among authors: hirata k. Breast Cancer Res Treat. 2010 Aug;122(3):699-710. doi: 10.1007/s10549-009-0600-1. Epub 2009 Oct 27. Breast Cancer Res Treat. 2010. PMID: 19859801
Association of microRNA-31 with BRAF mutation, colorectal cancer survival and serrated pathway.
Nosho K, Igarashi H, Nojima M, Ito M, Maruyama R, Yoshii S, Naito T, Sukawa Y, Mikami M, Sumioka W, Yamamoto E, Kurokawa S, Adachi Y, Takahashi H, Okuda H, Kusumi T, Hosokawa M, Fujita M, Hasegawa T, Okita K, Hirata K, Suzuki H, Yamamoto H, Shinomura Y. Nosho K, et al. Among authors: hirata k. Carcinogenesis. 2014 Apr;35(4):776-83. doi: 10.1093/carcin/bgt374. Epub 2013 Nov 15. Carcinogenesis. 2014. PMID: 24242331
Association of MicroRNA-31-5p with Clinical Efficacy of Anti-EGFR Therapy in Patients with Metastatic Colorectal Cancer.
Igarashi H, Kurihara H, Mitsuhashi K, Ito M, Okuda H, Kanno S, Naito T, Yoshii S, Takahashi H, Kusumi T, Hasegawa T, Sukawa Y, Adachi Y, Okita K, Hirata K, Imamura Y, Baba Y, Imai K, Suzuki H, Yamamoto H, Nosho K, Shinomura Y. Igarashi H, et al. Among authors: hirata k. Ann Surg Oncol. 2015 Aug;22(8):2640-8. doi: 10.1245/s10434-014-4264-7. Epub 2014 Dec 4. Ann Surg Oncol. 2015. PMID: 25472647
4,353 results