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Isoform-selective thiazolo[5,4-b]pyridine S1P1 agonists possessing acyclic amino carboxylate head-groups.
Reed AB, Lanman BA, Neira S, Harrington PE, Sham KK, Frohn M, Pickrell AJ, Tasker AS, Gore A, Fiorino M, Itano A, McElvain M, Middleton S, Morrison H, Xu H, Xu Y, Wong M, Cee VJ. Reed AB, et al. Among authors: neira s. Bioorg Med Chem Lett. 2012 Feb 15;22(4):1779-83. doi: 10.1016/j.bmcl.2011.12.073. Epub 2011 Dec 21. Bioorg Med Chem Lett. 2012. PMID: 22257889
Discovery of a Potent, S1P3-Sparing Benzothiazole Agonist of Sphingosine-1-Phosphate Receptor 1 (S1P1).
Lanman BA, Cee VJ, Cheruku SR, Frohn M, Golden J, Lin J, Lobera M, Marantz Y, Muller KM, Neira SC, Pickrell AJ, Rivenzon-Segal D, Schutz N, Sharadendu A, Yu X, Zhang Z, Buys J, Fiorino M, Gore A, Horner M, Itano A, McElvain M, Middleton S, Schrag M, Vargas HM, Xu H, Xu Y, Zhang X, Siu J, Bürli RW. Lanman BA, et al. Among authors: neira sc. ACS Med Chem Lett. 2010 Nov 9;2(2):102-6. doi: 10.1021/ml100228m. eCollection 2011 Feb 10. ACS Med Chem Lett. 2010. PMID: 24900287 Free PMC article.
Discovery of AMG 369, a Thiazolo[5,4-b]pyridine Agonist of S1P1 and S1P5.
Cee VJ, Frohn M, Lanman BA, Golden J, Muller K, Neira S, Pickrell A, Arnett H, Buys J, Gore A, Fiorino M, Horner M, Itano A, Lee MR, McElvain M, Middleton S, Schrag M, Rivenzon-Segal D, Vargas HM, Xu H, Xu Y, Zhang X, Siu J, Wong M, Bürli RW. Cee VJ, et al. Among authors: neira s. ACS Med Chem Lett. 2010 Dec 29;2(2):107-12. doi: 10.1021/ml100306h. eCollection 2011 Feb 10. ACS Med Chem Lett. 2010. PMID: 24900288 Free PMC article.
Corticotropin-Releasing Factor Modulates Binge-Like Ethanol Drinking in a Sex-Dependent Manner: Impact of Amygdala Deletion and Inhibition of a Central Amygdala to Lateral Hypothalamus Circuit.
Bendrath SC, Méndez HG, Dankert AM, Lerma-Cabrera JM, Carvajal F, Dornellas APS, Lee S, Neira S, Haun H, Delpire E, Navarro M, Kash TL, Thiele TE. Bendrath SC, et al. Among authors: neira s. Biol Psychiatry Glob Open Sci. 2024 Oct 25;5(1):100405. doi: 10.1016/j.bpsgos.2024.100405. eCollection 2025 Jan. Biol Psychiatry Glob Open Sci. 2024. PMID: 39660275 Free PMC article.
Inhibiting CRF Projections from the Central Amygdala to Lateral Hypothalamus and Amygdala Deletion of CRF Alters Binge-Like Ethanol Drinking in a Sex-Dependent Manner.
Bendrath SC, Méndez HG, Dankert AM, Lerma-Cabrera JM, Carvajal F, Dornellas-Loper AP, Lee S, Neira S, Haun H, Delpire E, Navarro M, Kash TL, Thiele TE. Bendrath SC, et al. Among authors: neira s. bioRxiv [Preprint]. 2024 Apr 13:2024.04.09.588750. doi: 10.1101/2024.04.09.588750. bioRxiv. 2024. Update in: Biol Psychiatry Glob Open Sci. 2024 Oct 25;5(1):100405. doi: 10.1016/j.bpsgos.2024.100405 PMID: 38645149 Free PMC article. Updated. Preprint.
Dynamic regulation of CeA gene expression during acute and protracted abstinence from chronic binge drinking of male and female C57BL/6J mice.
Méndez HG, Neira S, Flanigan ME, Haun HL, Boyt KM, Thiele TE, Kash TL. Méndez HG, et al. Among authors: neira s. bioRxiv [Preprint]. 2024 Feb 4:2024.02.02.578650. doi: 10.1101/2024.02.02.578650. bioRxiv. 2024. Update in: Alcohol. 2024 Nov;120:179-193. doi: 10.1016/j.alcohol.2024.06.005 PMID: 38352404 Free PMC article. Updated. Preprint.
43 results