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172 results

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Page 1
A semimechanistic pharmacokinetic-enzyme turnover model for rifampin autoinduction in adult tuberculosis patients.
Smythe W, Khandelwal A, Merle C, Rustomjee R, Gninafon M, Bocar Lo M, Sow OB, Olliaro PL, Lienhardt C, Horton J, Smith P, McIlleron H, Simonsson US. Smythe W, et al. Among authors: lienhardt c. Antimicrob Agents Chemother. 2012 Apr;56(4):2091-8. doi: 10.1128/AAC.05792-11. Epub 2012 Jan 17. Antimicrob Agents Chemother. 2012. PMID: 22252827 Free PMC article. Clinical Trial.
A pivotal registration phase III, multicenter, randomized tuberculosis controlled trial: design issues and lessons learnt from the Gatifloxacin for TB (OFLOTUB) project.
Merle CS, Sismanidis C, Sow OB, Gninafon M, Horton J, Lapujade O, Lo MB, Mitchinson DA, Perronne C, Portaels F, Odhiambo J, Olliaro P, Rustomjee R, Lienhardt C, Fielding K. Merle CS, et al. Among authors: lienhardt c. Trials. 2012 May 18;13:61. doi: 10.1186/1745-6215-13-61. Trials. 2012. PMID: 22607233 Free PMC article. Clinical Trial.
Evaluation of initial and steady-state gatifloxacin pharmacokinetics and dose in pulmonary tuberculosis patients by using monte carlo simulations.
Smythe W, Merle CS, Rustomjee R, Gninafon M, Lo MB, Bah-Sow O, Olliaro PL, Lienhardt C, Horton J, Smith P, McIlleron H, Simonsson US. Smythe W, et al. Among authors: lienhardt c. Antimicrob Agents Chemother. 2013 Sep;57(9):4164-71. doi: 10.1128/AAC.00479-13. Epub 2013 Jun 17. Antimicrob Agents Chemother. 2013. PMID: 23774436 Free PMC article. Clinical Trial.
A four-month gatifloxacin-containing regimen for treating tuberculosis.
Merle CS, Fielding K, Sow OB, Gninafon M, Lo MB, Mthiyane T, Odhiambo J, Amukoye E, Bah B, Kassa F, N'Diaye A, Rustomjee R, de Jong BC, Horton J, Perronne C, Sismanidis C, Lapujade O, Olliaro PL, Lienhardt C; OFLOTUB/Gatifloxacin for Tuberculosis Project. Merle CS, et al. Among authors: lienhardt c. N Engl J Med. 2014 Oct 23;371(17):1588-98. doi: 10.1056/NEJMoa1315817. N Engl J Med. 2014. PMID: 25337748 Free article. Clinical Trial.
Randomized pharmacokinetic evaluation of different rifabutin doses in African HIV- infected tuberculosis patients on lopinavir/ritonavir-based antiretroviral therapy.
Naiker S, Connolly C, Wiesner L, Kellerman T, Reddy T, Harries A, McIlleron H, Lienhardt C, Pym A. Naiker S, et al. Among authors: lienhardt c. BMC Pharmacol Toxicol. 2014 Nov 19;15:61. doi: 10.1186/2050-6511-15-61. BMC Pharmacol Toxicol. 2014. PMID: 25406657 Free PMC article. Clinical Trial.
First insights into circulating Mycobacterium tuberculosis complex lineages and drug resistance in Guinea.
Ejo M, Gehre F, Barry MD, Sow O, Bah NM, Camara M, Bah B, Uwizeye C, Nduwamahoro E, Fissette K, De Rijk P, Merle C, Olliaro P, Burgos M, Lienhardt C, Rigouts L, de Jong BC. Ejo M, et al. Among authors: lienhardt c. Infect Genet Evol. 2015 Jul;33:314-9. doi: 10.1016/j.meegid.2015.05.022. Epub 2015 May 21. Infect Genet Evol. 2015. PMID: 26004194 Free PMC article.
Effects on the QT Interval of a Gatifloxacin-Containing Regimen versus Standard Treatment of Pulmonary Tuberculosis.
Olliaro PL, Merle C, Mthiyane T, Bah B, Kassa F, Amukoye E, N Diaye A, Perronne C, Lienhardt C, McIlleron H, Fielding K. Olliaro PL, et al. Among authors: lienhardt c. Antimicrob Agents Chemother. 2017 Jun 27;61(7):e01834-16. doi: 10.1128/AAC.01834-16. Print 2017 Jul. Antimicrob Agents Chemother. 2017. PMID: 28438924 Free PMC article. Clinical Trial.
172 results