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Next generation sequencing of prostate cancer from a patient identifies a deficiency of methylthioadenosine phosphorylase, an exploitable tumor target.
Collins CC, Volik SV, Lapuk AV, Wang Y, Gout PW, Wu C, Xue H, Cheng H, Haegert A, Bell RH, Brahmbhatt S, Anderson S, Fazli L, Hurtado-Coll A, Rubin MA, Demichelis F, Beltran H, Hirst M, Marra M, Maher CA, Chinnaiyan AM, Gleave M, Bertino JR, Lubin M, Wang Y. Collins CC, et al. Among authors: hirst m. Mol Cancer Ther. 2012 Mar;11(3):775-83. doi: 10.1158/1535-7163.MCT-11-0826. Epub 2012 Jan 17. Mol Cancer Ther. 2012. PMID: 22252602 Free PMC article.
Epigenetics and human disease.
Hirst M, Marra MA. Hirst M, et al. Int J Biochem Cell Biol. 2009 Jan;41(1):136-46. doi: 10.1016/j.biocel.2008.09.011. Epub 2008 Sep 24. Int J Biochem Cell Biol. 2009. PMID: 18852064 Review.
Next-generation tag sequencing for cancer gene expression profiling.
Morrissy AS, Morin RD, Delaney A, Zeng T, McDonald H, Jones S, Zhao Y, Hirst M, Marra MA. Morrissy AS, et al. Among authors: hirst m. Genome Res. 2009 Oct;19(10):1825-35. doi: 10.1101/gr.094482.109. Epub 2009 Jun 18. Genome Res. 2009. PMID: 19541910 Free PMC article.
Identification of miR-145 and miR-146a as mediators of the 5q- syndrome phenotype.
Starczynowski DT, Kuchenbauer F, Argiropoulos B, Sung S, Morin R, Muranyi A, Hirst M, Hogge D, Marra M, Wells RA, Buckstein R, Lam W, Humphries RK, Karsan A. Starczynowski DT, et al. Among authors: hirst m. Nat Med. 2010 Jan;16(1):49-58. doi: 10.1038/nm.2054. Epub 2009 Nov 8. Nat Med. 2010. PMID: 19898489
SNVMix: predicting single nucleotide variants from next-generation sequencing of tumors.
Goya R, Sun MG, Morin RD, Leung G, Ha G, Wiegand KC, Senz J, Crisan A, Marra MA, Hirst M, Huntsman D, Murphy KP, Aparicio S, Shah SP. Goya R, et al. Among authors: hirst m. Bioinformatics. 2010 Mar 15;26(6):730-6. doi: 10.1093/bioinformatics/btq040. Epub 2010 Feb 3. Bioinformatics. 2010. PMID: 20130035 Free PMC article.
442 results