Santos-Sierra S - Search Results

1

Novel pharmacological chaperones that correct phenylketonuria in mice.

Santos-Sierra S, Kirchmair J, Perna AM, Reiss D, Kemter K, Röschinger W, Glossmann H, Gersting SW, Muntau AC, Wolber G, Lagler FB. Santos-Sierra S, et al. Hum Mol Genet. 2012 Apr 15;21(8):1877-87. doi: 10.1093/hmg/dds001. Epub 2012 Jan 13. Hum Mol Genet. 2012. PMID: 22246293

2

INH14, a Small-Molecule Urea Derivative, Inhibits the IKKα/β-Dependent TLR Inflammatory Response.

Drexel M, Kirchmair J, Santos-Sierra S. Drexel M, et al. Among authors: santos sierra s. Chembiochem. 2019 Mar 1;20(5):710-717. doi: 10.1002/cbic.201800647. Epub 2019 Jan 29. Chembiochem. 2019. PMID: 30447158 Free PMC article.

3

Prospective virtual screening in a sparse data scenario: design of small-molecule TLR2 antagonists.

Murgueitio MS, Henneke P, Glossmann H, Santos-Sierra S, Wolber G. Murgueitio MS, et al. Among authors: santos sierra s. ChemMedChem. 2014 Apr;9(4):813-22. doi: 10.1002/cmdc.201300445. Epub 2014 Jan 27. ChemMedChem. 2014. PMID: 24470159

4

Enhanced immunostimulatory activity of in silico discovered agonists of Toll-like receptor 2 (TLR2).

Murgueitio MS, Ebner S, Hörtnagl P, Rakers C, Bruckner R, Henneke P, Wolber G, Santos-Sierra S. Murgueitio MS, et al. Among authors: santos sierra s. Biochim Biophys Acta Gen Subj. 2017 Nov;1861(11 Pt A):2680-2689. doi: 10.1016/j.bbagen.2017.07.011. Epub 2017 Jul 19. Biochim Biophys Acta Gen Subj. 2017. PMID: 28734965

5

Anti-inflammatory activity of small-molecule antagonists of Toll-like receptor 2 (TLR2) in mice.

Wietzorrek G, Drexel M, Trieb M, Santos-Sierra S. Wietzorrek G, et al. Among authors: santos sierra s. Immunobiology. 2019 Jan;224(1):1-9. doi: 10.1016/j.imbio.2018.11.004. Epub 2018 Nov 20. Immunobiology. 2019. PMID: 30509503

6

Decoy peptides derived from the extracellular domain of toll-like receptor 2 (TLR2) show anti-inflammatory properties.

Ebner S, Trieb M, Schönfeld M, Wietzorrek G, Santos-Sierra S. Ebner S, et al. Among authors: santos sierra s. Bioorg Med Chem. 2018 Sep 1;26(16):4615-4623. doi: 10.1016/j.bmc.2018.07.013. Epub 2018 Jul 9. Bioorg Med Chem. 2018. PMID: 30093346

7

Toll-like receptor-dependent discrimination of streptococci.

Santos-Sierra S, Golenbock DT, Henneke P. Santos-Sierra S, et al. J Endotoxin Res. 2006;12(5):307-12. doi: 10.1179/096805106X118762. J Endotoxin Res. 2006. PMID: 17059694 Review.

8

Mal connects TLR2 to PI3Kinase activation and phagocyte polarization.

Santos-Sierra S, Deshmukh SD, Kalnitski J, Küenzi P, Wymann MP, Golenbock DT, Henneke P. Santos-Sierra S, et al. EMBO J. 2009 Jul 22;28(14):2018-27. doi: 10.1038/emboj.2009.158. Epub 2009 Jul 2. EMBO J. 2009. PMID: 19574958 Free PMC article.

9

Role of p38 and early growth response factor 1 in the macrophage response to group B streptococcus.

Kenzel S, Santos-Sierra S, Deshmukh SD, Moeller I, Ergin B, Fitzgerald KA, Lien E, Akira S, Golenbock DT, Henneke P. Kenzel S, et al. Infect Immun. 2009 Jun;77(6):2474-81. doi: 10.1128/IAI.01343-08. Epub 2009 Mar 30. Infect Immun. 2009. PMID: 19332535 Free PMC article.

10

Insulin modulates the inflammatory granulocyte response to streptococci via phosphatidylinositol 3-kinase.

Kenzel S, Mergen M, von Süßkind-Schwendi J, Wennekamp J, Deshmukh SD, Haeffner M, Triantafyllopoulou A, Fuchs S, Farmand S, Santos-Sierra S, Seufert J, van den Berg TK, Kuijpers TW, Henneke P. Kenzel S, et al. Among authors: santos sierra s. J Immunol. 2012 Nov 1;189(9):4582-91. doi: 10.4049/jimmunol.1200205. Epub 2012 Sep 26. J Immunol. 2012. PMID: 23018458 Free PMC article.

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