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Exploring use of unsupervised clustering to associate signaling profiles of GPCR ligands to clinical response.
Benredjem B, Gallion J, Pelletier D, Dallaire P, Charbonneau J, Cawkill D, Nagi K, Gosink M, Lukasheva V, Jenkinson S, Ren Y, Somps C, Murat B, Van Der Westhuizen E, Le Gouill C, Lichtarge O, Schmidt A, Bouvier M, Pineyro G. Benredjem B, et al. Among authors: van der westhuizen e. Nat Commun. 2019 Sep 9;10(1):4075. doi: 10.1038/s41467-019-11875-6. Nat Commun. 2019. PMID: 31501422 Free PMC article.
Structural insights into binding specificity, efficacy and bias of a β2AR partial agonist.
Masureel M, Zou Y, Picard LP, van der Westhuizen E, Mahoney JP, Rodrigues JPGLM, Mildorf TJ, Dror RO, Shaw DE, Bouvier M, Pardon E, Steyaert J, Sunahara RK, Weis WI, Zhang C, Kobilka BK. Masureel M, et al. Among authors: van der westhuizen e. Nat Chem Biol. 2018 Nov;14(11):1059-1066. doi: 10.1038/s41589-018-0145-x. Epub 2018 Oct 16. Nat Chem Biol. 2018. PMID: 30327561 Free PMC article.
Author Correction: Exploring use of unsupervised clustering to associate signaling profiles of GPCR ligands to clinical response.
Benredjem B, Gallion J, Pelletier D, Dallaire P, Charbonneau J, Cawkill D, Nagi K, Gosink M, Lukasheva V, Jenkinson S, Ren Y, Somps C, Murat B, Van Der Westhuizen E, Le Gouill C, Lichtarge O, Schmidt A, Bouvier M, Pineyro G. Benredjem B, et al. Among authors: van der westhuizen e. Nat Commun. 2020 Apr 16;11(1):1929. doi: 10.1038/s41467-020-15945-y. Nat Commun. 2020. PMID: 32300106 Free PMC article.
Publisher Correction: Structural insights into binding specificity, efficacy and bias of a β2AR partial agonist.
Masureel M, Zou Y, Picard LP, van der Westhuizen E, Mahoney JP, Rodrigues JPGLM, Mildorf TJ, Dror RO, Shaw DE, Bouvier M, Pardon E, Steyaert J, Sunahara RK, Weis WI, Zhang C, Kobilka BK. Masureel M, et al. Among authors: van der westhuizen e. Nat Chem Biol. 2019 Feb;15(2):205. doi: 10.1038/s41589-018-0182-5. Nat Chem Biol. 2019. PMID: 30504785
Assessment of the Molecular Mechanisms of Action of Novel 4-Phenylpyridine-2-One and 6-Phenylpyrimidin-4-One Allosteric Modulators at the M1 Muscarinic Acetylcholine Receptors.
van der Westhuizen ET, Spathis A, Khajehali E, Jörg M, Mistry SN, Capuano B, Tobin AB, Sexton PM, Scammells PJ, Valant C, Christopoulos A. van der Westhuizen ET, et al. Mol Pharmacol. 2018 Jul;94(1):770-783. doi: 10.1124/mol.118.111633. Epub 2018 Apr 24. Mol Pharmacol. 2018. PMID: 29691279 Free PMC article.
Endogenous allosteric modulators of G protein-coupled receptors.
van der Westhuizen ET, Valant C, Sexton PM, Christopoulos A. van der Westhuizen ET, et al. J Pharmacol Exp Ther. 2015 May;353(2):246-60. doi: 10.1124/jpet.114.221606. Epub 2015 Feb 3. J Pharmacol Exp Ther. 2015. PMID: 25650376 Review.
38 results