Rustum YM - Search Results

1

Ugt1a is required for the protective effect of selenium against irinotecan-induced toxicity.

Cao S, Durrani FA, Rustum YM, Yu YE. Cao S, et al. Among authors: rustum ym. Cancer Chemother Pharmacol. 2012 Apr;69(4):1107-11. doi: 10.1007/s00280-011-1820-8. Epub 2012 Jan 12. Cancer Chemother Pharmacol. 2012. PMID: 22237959 Free PMC article.

2

Therapeutic synergy between irinotecan and 5-fluorouracil against human tumor xenografts.

Azrak RG, Cao S, Slocum HK, Tóth K, Durrani FA, Yin MB, Pendyala L, Zhang W, McLeod HL, Rustum YM. Azrak RG, et al. Among authors: rustum ym. Clin Cancer Res. 2004 Feb 1;10(3):1121-9. doi: 10.1158/1078-0432.ccr-0913-3. Clin Cancer Res. 2004. PMID: 14871992

3

Selective modulation of the therapeutic efficacy of anticancer drugs by selenium containing compounds against human tumor xenografts.

Cao S, Durrani FA, Rustum YM. Cao S, et al. Among authors: rustum ym. Clin Cancer Res. 2004 Apr 1;10(7):2561-9. doi: 10.1158/1078-0432.ccr-03-0268. Clin Cancer Res. 2004. PMID: 15073137

4

Enhanced 7-ethyl-10-hydroxycamptothecin (SN-38) lethality by methylselenocysteine is associated with Chk2 phosphorylation at threonine-68 and down-regulation of Cdc6 expression.

Yin MB, Li ZR, Cao S, Durrani FA, Azrak RG, Frank C, Rustum YM. Yin MB, et al. Among authors: rustum ym. Mol Pharmacol. 2004 Jul;66(1):153-60. doi: 10.1124/mol.66.1.153. Mol Pharmacol. 2004. Retraction in: Mol Pharmacol. 2006 Mar;69(3):1074. PMID: 15213307 Retracted.

5

Synergistic antitumor activity of capecitabine in combination with irinotecan.

Cao S, Durrani FA, Rustum YM. Cao S, et al. Among authors: rustum ym. Clin Colorectal Cancer. 2005 Jan;4(5):336-43. doi: 10.3816/ccc.2005.n.007. Clin Colorectal Cancer. 2005. PMID: 15663838

6

Irinotecan pharmacokinetic and pharmacogenomic alterations induced by methylselenocysteine in human head and neck xenograft tumors.

Azrak RG, Yu J, Pendyala L, Smith PF, Cao S, Li X, Shannon WD, Durrani FA, McLeod HL, Rustum YM. Azrak RG, et al. Among authors: rustum ym. Mol Cancer Ther. 2005 May;4(5):843-54. doi: 10.1158/1535-7163.MCT-04-0315. Mol Cancer Ther. 2005. PMID: 15897249

7

Selenium protects against toxicity induced by anticancer drugs and augments antitumor activity: a highly selective, new, and novel approach for the treatment of solid tumors.

Fakih M, Cao S, Durrani FA, Rustum YM. Fakih M, et al. Among authors: rustum ym. Clin Colorectal Cancer. 2005 Jul;5(2):132-5. doi: 10.3816/ccc.2005.n.026. Clin Colorectal Cancer. 2005. PMID: 16098255 Review.

8

Efficacy of increasing the therapeutic index of irinotecan, plasma and tissue selenium concentrations is methylselenocysteine dose dependent.

Azrak RG, Cao S, Pendyala L, Durrani FA, Fakih M, Combs GF Jr, Prey J, Smith PF, Rustum YM. Azrak RG, et al. Among authors: rustum ym. Biochem Pharmacol. 2007 May 1;73(9):1280-7. doi: 10.1016/j.bcp.2006.12.020. Epub 2006 Dec 22. Biochem Pharmacol. 2007. PMID: 17239826 Free PMC article.

9

Hypoxia-specific drug tirapazamine does not abrogate hypoxic tumor cells in combination therapy with irinotecan and methylselenocysteine in well-differentiated human head and neck squamous cell carcinoma a253 xenografts.

Bhattacharya A, Tóth K, Durrani FA, Cao S, Slocum HK, Chintala S, Rustum YM. Bhattacharya A, et al. Among authors: rustum ym. Neoplasia. 2008 Aug;10(8):857-65. doi: 10.1593/neo.08424. Neoplasia. 2008. PMID: 18670644 Free PMC article.

10

Se-methylselenocysteine sensitizes hypoxic tumor cells to irinotecan by targeting hypoxia-inducible factor 1alpha.

Chintala S, Tóth K, Cao S, Durrani FA, Vaughan MM, Jensen RL, Rustum YM. Chintala S, et al. Among authors: rustum ym. Cancer Chemother Pharmacol. 2010 Oct;66(5):899-911. doi: 10.1007/s00280-009-1238-8. Epub 2010 Jan 12. Cancer Chemother Pharmacol. 2010. PMID: 20066420 Free PMC article.

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