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A novel retinoblastoma therapy from genomic and epigenetic analyses.
Zhang J, Benavente CA, McEvoy J, Flores-Otero J, Ding L, Chen X, Ulyanov A, Wu G, Wilson M, Wang J, Brennan R, Rusch M, Manning AL, Ma J, Easton J, Shurtleff S, Mullighan C, Pounds S, Mukatira S, Gupta P, Neale G, Zhao D, Lu C, Fulton RS, Fulton LL, Hong X, Dooling DJ, Ochoa K, Naeve C, Dyson NJ, Mardis ER, Bahrami A, Ellison D, Wilson RK, Downing JR, Dyer MA. Zhang J, et al. Among authors: manning al. Nature. 2012 Jan 11;481(7381):329-34. doi: 10.1038/nature10733. Nature. 2012. PMID: 22237022 Free PMC article.
pRB, a tumor suppressor with a stabilizing presence.
Manning AL, Dyson NJ. Manning AL, et al. Trends Cell Biol. 2011 Aug;21(8):433-41. doi: 10.1016/j.tcb.2011.05.003. Epub 2011 Jun 12. Trends Cell Biol. 2011. PMID: 21664133 Free PMC article. Review.
RB: mitotic implications of a tumour suppressor.
Manning AL, Dyson NJ. Manning AL, et al. Nat Rev Cancer. 2012 Feb 9;12(3):220-6. doi: 10.1038/nrc3216. Nat Rev Cancer. 2012. PMID: 22318235 Free PMC article. Review.
H4K20 methylation regulates quiescence and chromatin compaction.
Evertts AG, Manning AL, Wang X, Dyson NJ, Garcia BA, Coller HA. Evertts AG, et al. Among authors: manning al. Mol Biol Cell. 2013 Oct;24(19):3025-37. doi: 10.1091/mbc.E12-07-0529. Epub 2013 Aug 7. Mol Biol Cell. 2013. PMID: 23924899 Free PMC article.
Proteomic analysis of pRb loss highlights a signature of decreased mitochondrial oxidative phosphorylation.
Nicolay BN, Danielian PS, Kottakis F, Lapek JD Jr, Sanidas I, Miles WO, Dehnad M, Tschöp K, Gierut JJ, Manning AL, Morris R, Haigis K, Bardeesy N, Lees JA, Haas W, Dyson NJ. Nicolay BN, et al. Among authors: manning al. Genes Dev. 2015 Sep 1;29(17):1875-89. doi: 10.1101/gad.264127.115. Epub 2015 Aug 27. Genes Dev. 2015. PMID: 26314710 Free PMC article.
Identification of the kinase STK25 as an upstream activator of LATS signaling.
Lim S, Hermance N, Mudianto T, Mustaly HM, Mauricio IPM, Vittoria MA, Quinton RJ, Howell BW, Cornils H, Manning AL, Ganem NJ. Lim S, et al. Among authors: manning al. Nat Commun. 2019 Apr 4;10(1):1547. doi: 10.1038/s41467-019-09597-w. Nat Commun. 2019. PMID: 30948712 Free PMC article.
40 results