Baxendale RW - Search Results

1

Cold urticaria, immunodeficiency, and autoimmunity related to PLCG2 deletions.

Ombrello MJ, Remmers EF, Sun G, Freeman AF, Datta S, Torabi-Parizi P, Subramanian N, Bunney TD, Baxendale RW, Martins MS, Romberg N, Komarow H, Aksentijevich I, Kim HS, Ho J, Cruse G, Jung MY, Gilfillan AM, Metcalfe DD, Nelson C, O'Brien M, Wisch L, Stone K, Douek DC, Gandhi C, Wanderer AA, Lee H, Nelson SF, Shianna KV, Cirulli ET, Goldstein DB, Long EO, Moir S, Meffre E, Holland SM, Kastner DL, Katan M, Hoffman HM, Milner JD. Ombrello MJ, et al. Among authors: baxendale rw. N Engl J Med. 2012 Jan 26;366(4):330-8. doi: 10.1056/NEJMoa1102140. Epub 2012 Jan 11. N Engl J Med. 2012. PMID: 22236196 Free PMC article.

2

Structural and functional integration of the PLCγ interaction domains critical for regulatory mechanisms and signaling deregulation.

Bunney TD, Esposito D, Mas-Droux C, Lamber E, Baxendale RW, Martins M, Cole A, Svergun D, Driscoll PC, Katan M. Bunney TD, et al. Among authors: baxendale rw. Structure. 2012 Dec 5;20(12):2062-75. doi: 10.1016/j.str.2012.09.005. Epub 2012 Oct 11. Structure. 2012. PMID: 23063561 Free PMC article.

3

Regulatory links between PLC enzymes and Ras superfamily GTPases: signalling via PLCepsilon.

Bunney TD, Baxendale RW, Katan M. Bunney TD, et al. Among authors: baxendale rw. Adv Enzyme Regul. 2009;49(1):54-8. doi: 10.1016/j.advenzreg.2009.01.004. Adv Enzyme Regul. 2009. PMID: 19534025 Review. No abstract available.

4

Membrane environment exerts an important influence on rac-mediated activation of phospholipase Cγ2.

Everett KL, Buehler A, Bunney TD, Margineanu A, Baxendale RW, Vatter P, Retlich M, Walliser C, Manning HB, Neil MA, Dunsby C, French PM, Gierschik P, Katan M. Everett KL, et al. Among authors: baxendale rw. Mol Cell Biol. 2011 Mar;31(6):1240-51. doi: 10.1128/MCB.01408-10. Epub 2011 Jan 18. Mol Cell Biol. 2011. PMID: 21245382 Free PMC article.

5

Structural insights into formation of an active signaling complex between Rac and phospholipase C gamma 2.

Bunney TD, Opaleye O, Roe SM, Vatter P, Baxendale RW, Walliser C, Everett KL, Josephs MB, Christow C, Rodrigues-Lima F, Gierschik P, Pearl LH, Katan M. Bunney TD, et al. Among authors: baxendale rw. Mol Cell. 2009 Apr 24;34(2):223-33. doi: 10.1016/j.molcel.2009.02.023. Mol Cell. 2009. PMID: 19394299 Free article.

6

Tumor suppressor role of phospholipase C epsilon in Ras-triggered cancers.

Martins M, McCarthy A, Baxendale R, Guichard S, Magno L, Kessaris N, El-Bahrawy M, Yu P, Katan M. Martins M, et al. Proc Natl Acad Sci U S A. 2014 Mar 18;111(11):4239-44. doi: 10.1073/pnas.1311500111. Epub 2014 Mar 3. Proc Natl Acad Sci U S A. 2014. PMID: 24591640 Free PMC article.

7

Molecular cloning and characterization of a distinct human phosphodiesterase gene family: PDE11A.

Fawcett L, Baxendale R, Stacey P, McGrouther C, Harrow I, Soderling S, Hetman J, Beavo JA, Phillips SC. Fawcett L, et al. Proc Natl Acad Sci U S A. 2000 Mar 28;97(7):3702-7. doi: 10.1073/pnas.97.7.3702. Proc Natl Acad Sci U S A. 2000. PMID: 10725373 Free PMC article.

8

Immunolocalization of multiple Galpha subunits in mammalian spermatozoa and additional evidence for Galphas.

Baxendale RW, Fraser LR. Baxendale RW, et al. Mol Reprod Dev. 2003 May;65(1):104-13. doi: 10.1002/mrd.10295. Mol Reprod Dev. 2003. PMID: 12658639

9

First messenger regulation of capacitation via G protein-coupled mechanisms: a tale of serendipity and discovery.

Fraser LR, Adeoya-Osiguwa SA, Baxendale RW. Fraser LR, et al. Among authors: baxendale rw. Mol Hum Reprod. 2003 Dec;9(12):739-48. doi: 10.1093/molehr/gag097. Mol Hum Reprod. 2003. PMID: 14614035 Review.

10

Cloning and characterization of two splice variants of human phosphodiesterase 11A.

Hetman JM, Robas N, Baxendale R, Fidock M, Phillips SC, Soderling SH, Beavo JA. Hetman JM, et al. Proc Natl Acad Sci U S A. 2000 Nov 7;97(23):12891-5. doi: 10.1073/pnas.200355397. Proc Natl Acad Sci U S A. 2000. PMID: 11050148 Free PMC article.

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