Covey DF - Search Results

1

Oxysterols are allosteric activators of the oncoprotein Smoothened.

Nachtergaele S, Mydock LK, Krishnan K, Rammohan J, Schlesinger PH, Covey DF, Rohatgi R. Nachtergaele S, et al. Among authors: covey df. Nat Chem Biol. 2012 Jan 8;8(2):211-20. doi: 10.1038/nchembio.765. Nat Chem Biol. 2012. PMID: 22231273 Free PMC article.

2

Comparison of effects of U18666A and enantiomeric U18666A on sterol synthesis and induction of apoptosis.

Cenedella RJ, Sexton PS, Krishnan K, Covey DF. Cenedella RJ, et al. Among authors: covey df. Lipids. 2005 Jun;40(6):635-40. doi: 10.1007/s11745-005-1426-9. Lipids. 2005. PMID: 16149744

3

Side chain oxygenated cholesterol regulates cellular cholesterol homeostasis through direct sterol-membrane interactions.

Gale SE, Westover EJ, Dudley N, Krishnan K, Merlin S, Scherrer DE, Han X, Zhai X, Brockman HL, Brown RE, Covey DF, Schaffer JE, Schlesinger P, Ory DS. Gale SE, et al. Among authors: covey df. J Biol Chem. 2009 Jan 16;284(3):1755-64. doi: 10.1074/jbc.M807210200. Epub 2008 Nov 6. J Biol Chem. 2009. PMID: 18996837 Free PMC article.

4

Synthesis of 19-Trideuterated ent-Testosterone and the GABA(A) Receptor Potentiators ent-Androsterone and ent-Etiocholanolone.

Komarapuri S, Krishnan K, Covey DF. Komarapuri S, et al. Among authors: covey df. J Labelled Comp Radiopharm. 2008 Nov;51(14):430-434. doi: 10.1002/jlcr.1558. J Labelled Comp Radiopharm. 2008. PMID: 19122784 Free PMC article.

5

Oxysterols as non-genomic regulators of cholesterol homeostasis.

Bielska AA, Schlesinger P, Covey DF, Ory DS. Bielska AA, et al. Among authors: covey df. Trends Endocrinol Metab. 2012 Mar;23(3):99-106. doi: 10.1016/j.tem.2011.12.002. Epub 2012 Jan 11. Trends Endocrinol Metab. 2012. PMID: 22244444 Free PMC article.

6

The structural basis of cholesterol accessibility in membranes.

Olsen BN, Bielska AA, Lee T, Daily MD, Covey DF, Schlesinger PH, Baker NA, Ory DS. Olsen BN, et al. Among authors: covey df. Biophys J. 2013 Oct 15;105(8):1838-47. doi: 10.1016/j.bpj.2013.08.042. Biophys J. 2013. PMID: 24138860 Free PMC article.

7

Structure and function of the Smoothened extracellular domain in vertebrate Hedgehog signaling.

Nachtergaele S, Whalen DM, Mydock LK, Zhao Z, Malinauskas T, Krishnan K, Ingham PW, Covey DF, Siebold C, Rohatgi R. Nachtergaele S, et al. Among authors: covey df. Elife. 2013 Oct 29;2:e01340. doi: 10.7554/eLife.01340. Elife. 2013. PMID: 24171105 Free PMC article.

8

Tracking the subcellular fate of 20(s)-hydroxycholesterol with click chemistry reveals a transport pathway to the Golgi.

Peyrot SM, Nachtergaele S, Luchetti G, Mydock-McGrane LK, Fujiwara H, Scherrer D, Jallouk A, Schlesinger PH, Ory DS, Covey DF, Rohatgi R. Peyrot SM, et al. Among authors: covey df. J Biol Chem. 2014 Apr 18;289(16):11095-11110. doi: 10.1074/jbc.M113.540351. Epub 2014 Mar 4. J Biol Chem. 2014. PMID: 24596093 Free PMC article.

9

Anticonvulsant potencies of the enantiomers of the neurosteroids androsterone and etiocholanolone exceed those of the natural forms.

Zolkowska D, Dhir A, Krishnan K, Covey DF, Rogawski MA. Zolkowska D, et al. Among authors: covey df. Psychopharmacology (Berl). 2014 Sep;231(17):3325-32. doi: 10.1007/s00213-014-3546-x. Epub 2014 Apr 5. Psychopharmacology (Berl). 2014. PMID: 24705905 Free PMC article.

10

Side-chain oxysterols modulate cholesterol accessibility through membrane remodeling.

Bielska AA, Olsen BN, Gale SE, Mydock-McGrane L, Krishnan K, Baker NA, Schlesinger PH, Covey DF, Ory DS. Bielska AA, et al. Among authors: covey df. Biochemistry. 2014 May 13;53(18):3042-51. doi: 10.1021/bi5000096. Epub 2014 May 1. Biochemistry. 2014. PMID: 24758724 Free PMC article.

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