Deighton J - Search Results

1

BMP type II receptor deficiency confers resistance to growth inhibition by TGF-β in pulmonary artery smooth muscle cells: role of proinflammatory cytokines.

Davies RJ, Holmes AM, Deighton J, Long L, Yang X, Barker L, Walker C, Budd DC, Upton PD, Morrell NW. Davies RJ, et al. Among authors: deighton j. Am J Physiol Lung Cell Mol Physiol. 2012 Mar 15;302(6):L604-15. doi: 10.1152/ajplung.00309.2011. Epub 2012 Jan 6. Am J Physiol Lung Cell Mol Physiol. 2012. PMID: 22227206 Free PMC article.

2

TNFα drives pulmonary arterial hypertension by suppressing the BMP type-II receptor and altering NOTCH signalling.

Hurst LA, Dunmore BJ, Long L, Crosby A, Al-Lamki R, Deighton J, Southwood M, Yang X, Nikolic MZ, Herrera B, Inman GJ, Bradley JR, Rana AA, Upton PD, Morrell NW. Hurst LA, et al. Among authors: deighton j. Nat Commun. 2017 Jan 13;8:14079. doi: 10.1038/ncomms14079. Nat Commun. 2017. PMID: 28084316 Free PMC article.

3

Eotaxin-1/CC chemokine ligand 11: a novel eosinophil survival factor secreted by human pulmonary artery endothelial cells.

Farahi N, Cowburn AS, Upton PD, Deighton J, Sobolewski A, Gherardi E, Morrell NW, Chilvers ER. Farahi N, et al. Among authors: deighton j. J Immunol. 2007 Jul 15;179(2):1264-73. doi: 10.4049/jimmunol.179.2.1264. J Immunol. 2007. PMID: 17617619

4

A Potential Role for Exosomal Translationally Controlled Tumor Protein Export in Vascular Remodeling in Pulmonary Arterial Hypertension.

Ferrer E, Dunmore BJ, Hassan D, Ormiston ML, Moore S, Deighton J, Long L, Yang XD, Stewart DJ, Morrell NW. Ferrer E, et al. Among authors: deighton j. Am J Respir Cell Mol Biol. 2018 Oct;59(4):467-478. doi: 10.1165/rcmb.2017-0129OC. Am J Respir Cell Mol Biol. 2018. PMID: 29676587 Free PMC article.

5

Involvement of a ferroprotein sensor in hypoxia-mediated inhibition of neutrophil apoptosis.

Mecklenburgh KI, Walmsley SR, Cowburn AS, Wiesener M, Reed BJ, Upton PD, Deighton J, Greening AP, Chilvers ER. Mecklenburgh KI, et al. Among authors: deighton j. Blood. 2002 Oct 15;100(8):3008-16. doi: 10.1182/blood-2002-02-0454. Blood. 2002. PMID: 12351415 Free article.

6

The survival effect of TNF-alpha in human neutrophils is mediated via NF-kappa B-dependent IL-8 release.

Cowburn AS, Deighton J, Walmsley SR, Chilvers ER. Cowburn AS, et al. Among authors: deighton j. Eur J Immunol. 2004 Jun;34(6):1733-43. doi: 10.1002/eji.200425091. Eur J Immunol. 2004. PMID: 15162444 Free article.

7

Hypoxia causes IL-8 secretion, Charcot Leyden crystal formation, and suppression of corticosteroid-induced apoptosis in human eosinophils.

Porter LM, Cowburn AS, Farahi N, Deighton J, Farrow SN, Fiddler CA, Juss JK, Condliffe AM, Chilvers ER. Porter LM, et al. Among authors: deighton j. Clin Exp Allergy. 2017 Jun;47(6):770-784. doi: 10.1111/cea.12877. Epub 2017 Feb 3. Clin Exp Allergy. 2017. PMID: 28000962 Free article.

8

Aminopeptidase N (CD13) regulates tumor necrosis factor-alpha-induced apoptosis in human neutrophils.

Cowburn AS, Sobolewski A, Reed BJ, Deighton J, Murray J, Cadwallader KA, Bradley JR, Chilvers ER. Cowburn AS, et al. Among authors: deighton j. J Biol Chem. 2006 May 5;281(18):12458-67. doi: 10.1074/jbc.M511277200. Epub 2006 Mar 13. J Biol Chem. 2006. PMID: 16533817 Free article.

9

z-VAD-fmk augmentation of TNF alpha-stimulated neutrophil apoptosis is compound specific and does not involve the generation of reactive oxygen species.

Cowburn AS, White JF, Deighton J, Walmsley SR, Chilvers ER. Cowburn AS, et al. Among authors: deighton j. Blood. 2005 Apr 1;105(7):2970-2. doi: 10.1182/blood-2004-07-2870. Epub 2004 Nov 30. Blood. 2005. PMID: 15572588 Free article.

10

Bee venom immunotherapy induces a shift in cytokine responses from a TH-2 to a TH-1 dominant pattern: comparison of rush and conventional immunotherapy.

McHugh SM, Deighton J, Stewart AG, Lachmann PJ, Ewan PW. McHugh SM, et al. Among authors: deighton j. Clin Exp Allergy. 1995 Sep;25(9):828-38. doi: 10.1111/j.1365-2222.1995.tb00025.x. Clin Exp Allergy. 1995. PMID: 8564721 Clinical Trial.

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