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NF-κB negatively impacts the myogenic potential of muscle-derived stem cells.
Lu A, Proto JD, Guo L, Tang Y, Lavasani M, Tilstra JS, Niedernhofer LJ, Wang B, Guttridge DC, Robbins PD, Huard J. Lu A, et al. Among authors: tilstra js. Mol Ther. 2012 Mar;20(3):661-8. doi: 10.1038/mt.2011.261. Epub 2011 Dec 13. Mol Ther. 2012. PMID: 22158056 Free PMC article.
ISSLS prize winner: inhibition of NF-κB activity ameliorates age-associated disc degeneration in a mouse model of accelerated aging.
Nasto LA, Seo HY, Robinson AR, Tilstra JS, Clauson CL, Sowa GA, Ngo K, Dong Q, Pola E, Lee JY, Niedernhofer LJ, Kang JD, Robbins PD, Vo NV. Nasto LA, et al. Among authors: tilstra js. Spine (Phila Pa 1976). 2012 Oct 1;37(21):1819-25. doi: 10.1097/BRS.0b013e31824ee8f7. Spine (Phila Pa 1976). 2012. PMID: 22343279 Free PMC article.
NF-κB in Aging and Disease.
Tilstra JS, Clauson CL, Niedernhofer LJ, Robbins PD. Tilstra JS, et al. Aging Dis. 2011 Dec;2(6):449-65. Epub 2011 Dec 2. Aging Dis. 2011. PMID: 22396894 Free PMC article.
NF-κB inhibition delays DNA damage-induced senescence and aging in mice.
Tilstra JS, Robinson AR, Wang J, Gregg SQ, Clauson CL, Reay DP, Nasto LA, St Croix CM, Usas A, Vo N, Huard J, Clemens PR, Stolz DB, Guttridge DC, Watkins SC, Garinis GA, Wang Y, Niedernhofer LJ, Robbins PD. Tilstra JS, et al. J Clin Invest. 2012 Jul;122(7):2601-12. doi: 10.1172/JCI45785. Epub 2012 Jun 18. J Clin Invest. 2012. PMID: 22706308 Free PMC article.
Spontaneous DNA damage to the nuclear genome promotes senescence, redox imbalance and aging.
Robinson AR, Yousefzadeh MJ, Rozgaja TA, Wang J, Li X, Tilstra JS, Feldman CH, Gregg SQ, Johnson CH, Skoda EM, Frantz MC, Bell-Temin H, Pope-Varsalona H, Gurkar AU, Nasto LA, Robinson RAS, Fuhrmann-Stroissnigg H, Czerwinska J, McGowan SJ, Cantu-Medellin N, Harris JB, Maniar S, Ross MA, Trussoni CE, LaRusso NF, Cifuentes-Pagano E, Pagano PJ, Tudek B, Vo NV, Rigatti LH, Opresko PL, Stolz DB, Watkins SC, Burd CE, Croix CMS, Siuzdak G, Yates NA, Robbins PD, Wang Y, Wipf P, Kelley EE, Niedernhofer LJ. Robinson AR, et al. Among authors: tilstra js. Redox Biol. 2018 Jul;17:259-273. doi: 10.1016/j.redox.2018.04.007. Epub 2018 Apr 13. Redox Biol. 2018. PMID: 29747066 Free PMC article.
Ethyl pyruvate decreases HMGB1 release and ameliorates murine colitis.
Davé SH, Tilstra JS, Matsuoka K, Li F, DeMarco RA, Beer-Stolz D, Sepulveda AR, Fink MP, Lotze MT, Plevy SE. Davé SH, et al. Among authors: tilstra js. J Leukoc Biol. 2009 Sep;86(3):633-43. doi: 10.1189/jlb.1008662. Epub 2009 May 19. J Leukoc Biol. 2009. PMID: 19454652 Free PMC article.
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