Lodewyk MW - Search Results

1

Structure-activity relationships of cyanoquinolines with corrector-potentiator activity in ΔF508 cystic fibrosis transmembrane conductance regulator protein.

Knapp JM, Wood AB, Phuan PW, Lodewyk MW, Tantillo DJ, Verkman AS, Kurth MJ. Knapp JM, et al. Among authors: lodewyk mw. J Med Chem. 2012 Feb 9;55(3):1242-51. doi: 10.1021/jm201372q. Epub 2012 Jan 23. J Med Chem. 2012. PMID: 22214395 Free PMC article.

2

Potent s-cis-locked bithiazole correctors of DeltaF508 cystic fibrosis transmembrane conductance regulator cellular processing for cystic fibrosis therapy.

Yu GJ, Yoo CL, Yang B, Lodewyk MW, Meng L, El-Idreesy TT, Fettinger JC, Tantillo DJ, Verkman AS, Kurth MJ. Yu GJ, et al. Among authors: lodewyk mw. J Med Chem. 2008 Oct 9;51(19):6044-54. doi: 10.1021/jm800533c. Epub 2008 Sep 13. J Med Chem. 2008. PMID: 18788728 Free PMC article.

3

Constrained bithiazoles: small molecule correctors of defective ΔF508-CFTR protein trafficking.

Coffman KC, Nguyen HH, Phuan PW, Hudson BM, Yu GJ, Bagdasarian AL, Montgomery D, Lodewyk MW, Yang B, Yoo CL, Verkman AS, Tantillo DJ, Kurth MJ. Coffman KC, et al. Among authors: lodewyk mw. J Med Chem. 2014 Aug 14;57(15):6729-38. doi: 10.1021/jm5007885. Epub 2014 Jul 25. J Med Chem. 2014. PMID: 25061695 Free PMC article.

4

Computational studies on biosynthetic carbocation rearrangements leading to sativene, cyclosativene, alpha-ylangene, and beta-ylangene.

Lodewyk MW, Gutta P, Tantillo DJ. Lodewyk MW, et al. J Org Chem. 2008 Sep 5;73(17):6570-9. doi: 10.1021/jo800868r. Epub 2008 Aug 6. J Org Chem. 2008. PMID: 18681400

5

Mechanisms for formation of diazocinones, pyridazines, and pyrazolines from tetrazines--oxyanion-accelerated pericyclic cascades?

Lodewyk MW, Kurth MJ, Tantillo DJ. Lodewyk MW, et al. J Org Chem. 2009 Jul 3;74(13):4804-11. doi: 10.1021/jo900565y. J Org Chem. 2009. PMID: 19485385

6

Synthesis of substituted chromanones: an organocatalytic aldol/oxa-Michael reaction.

Butler JD, Conrad WE, Lodewyk MW, Fettinger JC, Tantillo DJ, Kurth MJ. Butler JD, et al. Among authors: lodewyk mw. Org Lett. 2010 Aug 6;12(15):3410-3. doi: 10.1021/ol101221c. Org Lett. 2010. PMID: 20617821 Free PMC article.

7

Prediction of the structure of nobilisitine a using computed NMR chemical shifts.

Lodewyk MW, Tantillo DJ. Lodewyk MW, et al. J Nat Prod. 2011 May 27;74(5):1339-43. doi: 10.1021/np2000446. Epub 2011 Apr 6. J Nat Prod. 2011. PMID: 21469691

8

A divergent approach to the synthesis of the yohimbinoid alkaloids venenatine and alstovenine.

Lebold TP, Wood JL, Deitch J, Lodewyk MW, Tantillo DJ, Sarpong R. Lebold TP, et al. Among authors: lodewyk mw. Nat Chem. 2013 Feb;5(2):126-31. doi: 10.1038/nchem.1528. Epub 2012 Dec 23. Nat Chem. 2013. PMID: 23344433 Free PMC article.

9

Pentalenene formation mechanisms redux.

Lodewyk MW, Willenbring D, Tantillo DJ. Lodewyk MW, et al. Org Biomol Chem. 2014 Feb 14;12(6):887-94. doi: 10.1039/c3ob42005a. Org Biomol Chem. 2014. PMID: 24326700

10

Cyclopenta[b]pyrroles from triazines: synthetic and mechanistic studies.

Ye L, Haddadin MJ, Lodewyk MW, Ferreira AJ, Fettinger JC, Tantillo DJ, Kurth MJ. Ye L, et al. Among authors: lodewyk mw. Org Lett. 2010 Jan 1;12(1):164-7. doi: 10.1021/ol902559u. Org Lett. 2010. PMID: 19961148

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