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Human endogenous retrovirus K(HML-2) Gag- and Env-specific T-cell responses are infrequently detected in HIV-1-infected subjects using standard peptide matrix-based screening.
Jones RB, John VM, Hunter DV, Martin E, Mujib S, Mihajlovic V, Burgers PC, Luider TM, Gyenes G, Sheppard NC, Sengupta D, Tandon R, Yue FY, Benko E, Kovacs C, Nixon DF, Ostrowski MA. Jones RB, et al. Among authors: benko e. Clin Vaccine Immunol. 2012 Feb;19(2):288-92. doi: 10.1128/CVI.05583-11. Epub 2011 Dec 28. Clin Vaccine Immunol. 2012. PMID: 22205657 Free PMC article.
Loss of the signaling adaptor TRAF1 causes CD8+ T cell dysregulation during human and murine chronic infection.
Wang C, McPherson AJ, Jones RB, Kawamura KS, Lin GH, Lang PA, Ambagala T, Pellegrini M, Calzascia T, Aidarus N, Elford AR, Yue FY, Kremmer E, Kovacs CM, Benko E, Tremblay C, Routy JP, Bernard NF, Ostrowski MA, Ohashi PS, Watts TH. Wang C, et al. Among authors: benko e. J Exp Med. 2012 Jan 16;209(1):77-91. doi: 10.1084/jem.20110675. Epub 2011 Dec 19. J Exp Med. 2012. PMID: 22184633 Free PMC article.
Antigen-independent induction of Tim-3 expression on human T cells by the common γ-chain cytokines IL-2, IL-7, IL-15, and IL-21 is associated with proliferation and is dependent on the phosphoinositide 3-kinase pathway.
Mujib S, Jones RB, Lo C, Aidarus N, Clayton K, Sakhdari A, Benko E, Kovacs C, Ostrowski MA. Mujib S, et al. Among authors: benko e. J Immunol. 2012 Apr 15;188(8):3745-56. doi: 10.4049/jimmunol.1102609. Epub 2012 Mar 14. J Immunol. 2012. PMID: 22422881
Tim-3 negatively regulates cytotoxicity in exhausted CD8+ T cells in HIV infection.
Sakhdari A, Mujib S, Vali B, Yue FY, MacParland S, Clayton K, Jones RB, Liu J, Lee EY, Benko E, Kovacs C, Gommerman J, Kaul R, Ostrowski MA. Sakhdari A, et al. Among authors: benko e. PLoS One. 2012;7(7):e40146. doi: 10.1371/journal.pone.0040146. Epub 2012 Jul 5. PLoS One. 2012. PMID: 22792231 Free PMC article.
75 results