Dominy JE Jr - Search Results

1

The deacetylase Sirt6 activates the acetyltransferase GCN5 and suppresses hepatic gluconeogenesis.

Dominy JE Jr, Lee Y, Jedrychowski MP, Chim H, Jurczak MJ, Camporez JP, Ruan HB, Feldman J, Pierce K, Mostoslavsky R, Denu JM, Clish CB, Yang X, Shulman GI, Gygi SP, Puigserver P. Dominy JE Jr, et al. Mol Cell. 2012 Dec 28;48(6):900-13. doi: 10.1016/j.molcel.2012.09.030. Epub 2012 Nov 8. Mol Cell. 2012. PMID: 23142079 Free PMC article.

2

The cAMP/PKA pathway rapidly activates SIRT1 to promote fatty acid oxidation independently of changes in NAD(+).

Gerhart-Hines Z, Dominy JE Jr, Blättler SM, Jedrychowski MP, Banks AS, Lim JH, Chim H, Gygi SP, Puigserver P. Gerhart-Hines Z, et al. Among authors: dominy je jr. Mol Cell. 2011 Dec 23;44(6):851-63. doi: 10.1016/j.molcel.2011.12.005. Mol Cell. 2011. PMID: 22195961 Free PMC article.

3

Thiol dioxygenases: unique families of cupin proteins.

Stipanuk MH, Simmons CR, Karplus PA, Dominy JE Jr. Stipanuk MH, et al. Among authors: dominy je jr. Amino Acids. 2011 Jun;41(1):91-102. doi: 10.1007/s00726-010-0518-2. Epub 2010 Mar 1. Amino Acids. 2011. PMID: 20195658 Free PMC article. Review.

4

Nutrient-dependent regulation of PGC-1alpha's acetylation state and metabolic function through the enzymatic activities of Sirt1/GCN5.

Dominy JE Jr, Lee Y, Gerhart-Hines Z, Puigserver P. Dominy JE Jr, et al. Biochim Biophys Acta. 2010 Aug;1804(8):1676-83. doi: 10.1016/j.bbapap.2009.11.023. Epub 2009 Dec 11. Biochim Biophys Acta. 2010. PMID: 20005308 Free PMC article. Review.

5

Measurement of Cysteine Dioxygenase Activity and Protein Abundance.

Stipanuk MH, Dominy JE Jr, Ueki I, Hirschberger LL. Stipanuk MH, et al. Among authors: dominy je jr. Curr Protoc Toxicol. 2008 Nov 1;38:6.15.1-6.15.25. doi: 10.1002/0471140856.tx0615s38. Curr Protoc Toxicol. 2008. PMID: 19885389 Free PMC article.

6

Cysteine dioxygenase: a robust system for regulation of cellular cysteine levels.

Stipanuk MH, Ueki I, Dominy JE Jr, Simmons CR, Hirschberger LL. Stipanuk MH, et al. Among authors: dominy je jr. Amino Acids. 2009 May;37(1):55-63. doi: 10.1007/s00726-008-0202-y. Epub 2008 Nov 15. Amino Acids. 2009. PMID: 19011731 Free PMC article. Review.

7

A putative Fe2+-bound persulfenate intermediate in cysteine dioxygenase.

Simmons CR, Krishnamoorthy K, Granett SL, Schuller DJ, Dominy JE Jr, Begley TP, Stipanuk MH, Karplus PA. Simmons CR, et al. Among authors: dominy je jr. Biochemistry. 2008 Nov 4;47(44):11390-2. doi: 10.1021/bi801546n. Epub 2008 Oct 11. Biochemistry. 2008. PMID: 18847220 Free PMC article.

8

Synthesis of amino acid cofactor in cysteine dioxygenase is regulated by substrate and represents a novel post-translational regulation of activity.

Dominy JE Jr, Hwang J, Guo S, Hirschberger LL, Zhang S, Stipanuk MH. Dominy JE Jr, et al. J Biol Chem. 2008 May 2;283(18):12188-201. doi: 10.1074/jbc.M800044200. Epub 2008 Feb 28. J Biol Chem. 2008. PMID: 18308719 Free PMC article.

9

HepG2/C3A cells respond to cysteine deprivation by induction of the amino acid deprivation/integrated stress response pathway.

Lee JI, Dominy JE Jr, Sikalidis AK, Hirschberger LL, Wang W, Stipanuk MH. Lee JI, et al. Among authors: dominy je jr. Physiol Genomics. 2008 Apr 22;33(2):218-29. doi: 10.1152/physiolgenomics.00263.2007. Epub 2008 Feb 19. Physiol Genomics. 2008. PMID: 18285520

10

Discovery and characterization of a second mammalian thiol dioxygenase, cysteamine dioxygenase.

Dominy JE Jr, Simmons CR, Hirschberger LL, Hwang J, Coloso RM, Stipanuk MH. Dominy JE Jr, et al. J Biol Chem. 2007 Aug 31;282(35):25189-98. doi: 10.1074/jbc.M703089200. Epub 2007 Jun 20. J Biol Chem. 2007. PMID: 17581819 Free article.

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