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Characterization of the substituted N-triazole oxindole TROX-1, a small-molecule, state-dependent inhibitor of Ca(V)2 calcium channels.
Swensen AM, Herrington J, Bugianesi RM, Dai G, Haedo RJ, Ratliff KS, Smith MM, Warren VA, Arneric SP, Eduljee C, Parker D, Snutch TP, Hoyt SB, London C, Duffy JL, Kaczorowski GJ, McManus OB. Swensen AM, et al. Among authors: snutch tp. Mol Pharmacol. 2012 Mar;81(3):488-97. doi: 10.1124/mol.111.075226. Epub 2011 Dec 21. Mol Pharmacol. 2012. PMID: 22188924
Differential inhibition of T-type calcium channels by neuroleptics.
Santi CM, Cayabyab FS, Sutton KG, McRory JE, Mezeyova J, Hamming KS, Parker D, Stea A, Snutch TP. Santi CM, et al. Among authors: snutch tp. J Neurosci. 2002 Jan 15;22(2):396-403. doi: 10.1523/JNEUROSCI.22-02-00396.2002. J Neurosci. 2002. PMID: 11784784 Free PMC article.
Role of voltage-gated calcium channels in ascending pain pathways.
Zamponi GW, Lewis RJ, Todorovic SM, Arneric SP, Snutch TP. Zamponi GW, et al. Among authors: snutch tp. Brain Res Rev. 2009 Apr;60(1):84-9. doi: 10.1016/j.brainresrev.2008.12.021. Epub 2008 Dec 31. Brain Res Rev. 2009. PMID: 19162069 Free PMC article. Review.
Analgesic effects of a substituted N-triazole oxindole (TROX-1), a state-dependent, voltage-gated calcium channel 2 blocker.
Abbadie C, McManus OB, Sun SY, Bugianesi RM, Dai G, Haedo RJ, Herrington JB, Kaczorowski GJ, Smith MM, Swensen AM, Warren VA, Williams B, Arneric SP, Eduljee C, Snutch TP, Tringham EW, Jochnowitz N, Liang A, Euan MacIntyre D, McGowan E, Mistry S, White VV, Hoyt SB, London C, Lyons KA, Bunting PB, Volksdorf S, Duffy JL. Abbadie C, et al. Among authors: snutch tp. J Pharmacol Exp Ther. 2010 Aug;334(2):545-55. doi: 10.1124/jpet.110.166363. Epub 2010 May 3. J Pharmacol Exp Ther. 2010. PMID: 20439438
A novel slow-inactivation-specific ion channel modulator attenuates neuropathic pain.
Hildebrand ME, Smith PL, Bladen C, Eduljee C, Xie JY, Chen L, Fee-Maki M, Doering CJ, Mezeyova J, Zhu Y, Belardetti F, Pajouhesh H, Parker D, Arneric SP, Parmar M, Porreca F, Tringham E, Zamponi GW, Snutch TP. Hildebrand ME, et al. Among authors: snutch tp. Pain. 2011 Apr;152(4):833-843. doi: 10.1016/j.pain.2010.12.035. Epub 2011 Feb 23. Pain. 2011. PMID: 21349638
T-type calcium channel blockers that attenuate thalamic burst firing and suppress absence seizures.
Tringham E, Powell KL, Cain SM, Kuplast K, Mezeyova J, Weerapura M, Eduljee C, Jiang X, Smith P, Morrison JL, Jones NC, Braine E, Rind G, Fee-Maki M, Parker D, Pajouhesh H, Parmar M, O'Brien TJ, Snutch TP. Tringham E, et al. Among authors: snutch tp. Sci Transl Med. 2012 Feb 15;4(121):121ra19. doi: 10.1126/scitranslmed.3003120. Sci Transl Med. 2012. PMID: 22344687
202 results