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Indole-3-carbinol triggers aryl hydrocarbon receptor-dependent estrogen receptor (ER)alpha protein degradation in breast cancer cells disrupting an ERalpha-GATA3 transcriptional cross-regulatory loop.
Marconett CN, Sundar SN, Poindexter KM, Stueve TR, Bjeldanes LF, Firestone GL. Marconett CN, et al. Among authors: poindexter km. Mol Biol Cell. 2010 Apr 1;21(7):1166-77. doi: 10.1091/mbc.e09-08-0689. Epub 2010 Feb 3. Mol Biol Cell. 2010. PMID: 20130088 Free PMC article.