Wills M - Search Results

1

A novel neuroprotective therapy for Parkinson's disease using a viral noncoding RNA that protects mitochondrial complex I activity.

Kuan WL, Poole E, Fletcher M, Karniely S, Tyers P, Wills M, Barker RA, Sinclair JH. Kuan WL, et al. Among authors: wills m. J Exp Med. 2012 Jan 16;209(1):1-10. doi: 10.1084/jem.20111126. Epub 2011 Dec 19. J Exp Med. 2012. PMID: 22184634 Free PMC article.

2

Human cytomegalovirus and immunopathology.

Sissons JG, Carmichael AJ, McKinney N, Sinclair JH, Wills MR. Sissons JG, et al. Among authors: wills mr. Springer Semin Immunopathol. 2002;24(2):169-85. doi: 10.1007/s00281-002-0104-0. Springer Semin Immunopathol. 2002. PMID: 12503063 Review. No abstract available.

3

Human cytomegalovirus encodes an MHC class I-like molecule (UL142) that functions to inhibit NK cell lysis.

Wills MR, Ashiru O, Reeves MB, Okecha G, Trowsdale J, Tomasec P, Wilkinson GW, Sinclair J, Sissons JG. Wills MR, et al. J Immunol. 2005 Dec 1;175(11):7457-65. doi: 10.4049/jimmunol.175.11.7457. J Immunol. 2005. PMID: 16301653

4

The co-speciation of human cytomegalovirus (HCMV) with its human host has enabled this human pathogen to evolve multiple mechanisms to allow it to be carried, generally sub-clinically, for the lifetime of the host in the face of a robust immune response. Preface.

Wills M, Sinclair J. Wills M, et al. Virus Res. 2011 May;157(2):127. doi: 10.1016/j.virusres.2010.11.002. Epub 2010 Nov 13. Virus Res. 2011. PMID: 21078350 No abstract available.

5

Human cytomegalovirus latency alters the cellular secretome, inducing cluster of differentiation (CD)4+ T-cell migration and suppression of effector function.

Mason GM, Poole E, Sissons JG, Wills MR, Sinclair JH. Mason GM, et al. Among authors: wills mr. Proc Natl Acad Sci U S A. 2012 Sep 4;109(36):14538-43. doi: 10.1073/pnas.1204836109. Epub 2012 Jul 23. Proc Natl Acad Sci U S A. 2012. PMID: 22826250 Free PMC article.

6

Human cytomegalovirus latency-associated proteins elicit immune-suppressive IL-10 producing CD4⁺ T cells.

Mason GM, Jackson S, Okecha G, Poole E, Sissons JG, Sinclair J, Wills MR. Mason GM, et al. Among authors: wills mr. PLoS Pathog. 2013;9(10):e1003635. doi: 10.1371/journal.ppat.1003635. Epub 2013 Oct 10. PLoS Pathog. 2013. PMID: 24130479 Free PMC article. Clinical Trial.

7

The immunology of human cytomegalovirus latency: could latent infection be cleared by novel immunotherapeutic strategies?

Wills MR, Poole E, Lau B, Krishna B, Sinclair JH. Wills MR, et al. Cell Mol Immunol. 2015 Mar;12(2):128-38. doi: 10.1038/cmi.2014.75. Epub 2014 Aug 18. Cell Mol Immunol. 2015. PMID: 25132454 Free PMC article. Review.

8

Latency-associated viral interleukin-10 (IL-10) encoded by human cytomegalovirus modulates cellular IL-10 and CCL8 Secretion during latent infection through changes in the cellular microRNA hsa-miR-92a.

Poole E, Avdic S, Hodkinson J, Jackson S, Wills M, Slobedman B, Sinclair J. Poole E, et al. Among authors: wills m. J Virol. 2014 Dec;88(24):13947-55. doi: 10.1128/JVI.02424-14. Epub 2014 Sep 24. J Virol. 2014. PMID: 25253336 Free PMC article.

9

Transient activation of human cytomegalovirus lytic gene expression during latency allows cytotoxic T cell killing of latently infected cells.

Krishna BA, Lau B, Jackson SE, Wills MR, Sinclair JH, Poole E. Krishna BA, et al. Among authors: wills mr. Sci Rep. 2016 Apr 19;6:24674. doi: 10.1038/srep24674. Sci Rep. 2016. PMID: 27091512 Free PMC article.

10

Human cytomegalovirus miR-UL112-1 promotes the down-regulation of viral immediate early-gene expression during latency to prevent T-cell recognition of latently infected cells.

Lau B, Poole E, Van Damme E, Bunkens L, Sowash M, King H, Murphy E, Wills M, Van Loock M, Sinclair J. Lau B, et al. Among authors: wills m. J Gen Virol. 2016 Sep;97(9):2387-2398. doi: 10.1099/jgv.0.000546. Epub 2016 Jul 13. J Gen Virol. 2016. PMID: 27411311 Free PMC article.

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