Liu M - Search Results

1

Development of a high-throughput screen targeting caspase-8-mediated cleavage of the amyloid precursor protein.

Hart MJ, Glicksman M, Liu M, Sharma MK, Cuny G, Galvan V. Hart MJ, et al. Among authors: liu m. Anal Biochem. 2012 Feb 15;421(2):467-76. doi: 10.1016/j.ab.2011.11.020. Epub 2011 Dec 1. Anal Biochem. 2012. PMID: 22178911

2

Development of a mechanism-based high-throughput screen assay for leucine-rich repeat kinase 2--discovery of LRRK2 inhibitors.

Liu M, Poulose S, Schuman E, Zaitsev AD, Dobson B, Auerbach K, Seyb K, Cuny GD, Glicksman MA, Stein RL, Yue Z. Liu M, et al. Anal Biochem. 2010 Sep 15;404(2):186-92. doi: 10.1016/j.ab.2010.05.033. Epub 2010 Jun 2. Anal Biochem. 2010. PMID: 20566370 Free PMC article.

3

Kinetic mechanistic studies of wild-type leucine-rich repeat kinase 2: characterization of the kinase and GTPase activities.

Liu M, Dobson B, Glicksman MA, Yue Z, Stein RL. Liu M, et al. Biochemistry. 2010 Mar 9;49(9):2008-17. doi: 10.1021/bi901851y. Biochemistry. 2010. PMID: 20146535 Free PMC article.

4

Kinetic-based high-throughput screening assay to discover novel classes of macrophage migration inhibitory factor inhibitors.

Ouertatani-Sakouhi H, Liu M, El-Turk F, Cuny GD, Glicksman MA, Lashuel HA. Ouertatani-Sakouhi H, et al. Among authors: liu m. J Biomol Screen. 2010 Apr;15(4):347-58. doi: 10.1177/1087057110363825. Epub 2010 Mar 15. J Biomol Screen. 2010. PMID: 20231420

5

Kinetic mechanistic studies of Cdk5/p25-catalyzed H1P phosphorylation: metal effect and solvent kinetic isotope effect.

Liu M, Girma E, Glicksman MA, Stein RL. Liu M, et al. Biochemistry. 2010 Jun 15;49(23):4921-9. doi: 10.1021/bi100244j. Biochemistry. 2010. PMID: 20491486 Free PMC article.

6

Kinetic, mechanistic, and structural modeling studies of truncated wild-type leucine-rich repeat kinase 2 and the G2019S mutant.

Liu M, Kang S, Ray S, Jackson J, Zaitsev AD, Gerber SA, Cuny GD, Glicksman MA. Liu M, et al. Biochemistry. 2011 Nov 1;50(43):9399-408. doi: 10.1021/bi201173d. Epub 2011 Oct 7. Biochemistry. 2011. PMID: 21961647 Free PMC article.

7

Enzymatic Characterization of ER Stress-Dependent Kinase, PERK, and Development of a High-Throughput Assay for Identification of PERK Inhibitors.

Pytel D, Seyb K, Liu M, Ray SS, Concannon J, Huang M, Cuny GD, Diehl JA, Glicksman MA. Pytel D, et al. Among authors: liu m. J Biomol Screen. 2014 Aug;19(7):1024-34. doi: 10.1177/1087057114525853. Epub 2014 Mar 5. J Biomol Screen. 2014. PMID: 24598103 Free PMC article.

8

Type II kinase inhibitors show an unexpected inhibition mode against Parkinson's disease-linked LRRK2 mutant G2019S.

Liu M, Bender SA, Cuny GD, Sherman W, Glicksman M, Ray SS. Liu M, et al. Biochemistry. 2013 Mar 12;52(10):1725-36. doi: 10.1021/bi3012077. Epub 2013 Mar 1. Biochemistry. 2013. PMID: 23379419 Free PMC article.

9

Kinetic studies of Cdk5/p25 kinase: phosphorylation of tau and complex inhibition by two prototype inhibitors.

Liu M, Choi S, Cuny GD, Ding K, Dobson BC, Glicksman MA, Auerbach K, Stein RL. Liu M, et al. Biochemistry. 2008 Aug 12;47(32):8367-77. doi: 10.1021/bi800732v. Epub 2008 Jul 18. Biochemistry. 2008. PMID: 18636751

10

A high-content screen identifies novel compounds that inhibit stress-induced TDP-43 cellular aggregation and associated cytotoxicity.

Boyd JD, Lee P, Feiler MS, Zauur N, Liu M, Concannon J, Ebata A, Wolozin B, Glicksman MA. Boyd JD, et al. Among authors: liu m. J Biomol Screen. 2014 Jan;19(1):44-56. doi: 10.1177/1087057113501553. Epub 2013 Sep 9. J Biomol Screen. 2014. PMID: 24019256 Free PMC article.

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