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Mixture model for sub-phenotyping in GWAS.
Warde-Farley D, Brudno M, Morris Q, Goldenberg A. Warde-Farley D, et al. Among authors: goldenberg a. Pac Symp Biocomput. 2012:363-74. Pac Symp Biocomput. 2012. PMID: 22174291 Free article.
Predicting node characteristics from molecular networks.
Mostafavi S, Goldenberg A, Morris Q. Mostafavi S, et al. Among authors: goldenberg a. Methods Mol Biol. 2011;781:399-414. doi: 10.1007/978-1-61779-276-2_20. Methods Mol Biol. 2011. PMID: 21877293
Labeling nodes using three degrees of propagation.
Mostafavi S, Goldenberg A, Morris Q. Mostafavi S, et al. Among authors: goldenberg a. PLoS One. 2012;7(12):e51947. doi: 10.1371/journal.pone.0051947. Epub 2012 Dec 28. PLoS One. 2012. PMID: 23284828 Free PMC article.
Identifying cancer specific functionally relevant miRNAs from gene expression and miRNA-to-gene networks using regularized regression.
Mezlini AM, Wang B, Deshwar A, Morris Q, Goldenberg A. Mezlini AM, et al. Among authors: goldenberg a. PLoS One. 2013 Oct 2;8(10):e73168. doi: 10.1371/journal.pone.0073168. eCollection 2013. PLoS One. 2013. PMID: 24098326 Free PMC article.
Our method is based on a linear regression with an elastic net regularization. Our simulations show that, with our method, the active miRNAs can be detected with high accuracy and our approach is robust to high levels of noise and missing information. ...The code is availa …
Our method is based on a linear regression with an elastic net regularization. Our simulations show that, with our method, the active …
JBASE: Joint Bayesian Analysis of Subphenotypes and Epistasis.
Colak R, Kim T, Kazan H, Oh Y, Cruz M, Valladares-Salgado A, Peralta J, Escobedo J, Parra EJ, Kim PM, Goldenberg A. Colak R, et al. Among authors: goldenberg a. Bioinformatics. 2016 Jan 15;32(2):203-10. doi: 10.1093/bioinformatics/btv504. Epub 2015 Sep 26. Bioinformatics. 2016. PMID: 26411870 Free PMC article.
JBASE explores two major reasons of missing heritability: interactions between genetic variants, a phenomenon known as epistasis and phenotypic heterogeneity, addressed via subphenotyping. ...We successfully replicated these subphenotypes and epistatic modules in an indepe …
JBASE explores two major reasons of missing heritability: interactions between genetic variants, a phenomenon known as epistasis and …
660 results