Busacca S - Search Results

1

Vorinostat/SAHA-induced apoptosis in malignant mesothelioma is FLIP/caspase 8-dependent and HR23B-independent.

Hurwitz JL, Stasik I, Kerr EM, Holohan C, Redmond KM, McLaughlin KM, Busacca S, Barbone D, Broaddus VC, Gray SG, O'Byrne KJ, Johnston PG, Fennell DA, Longley DB. Hurwitz JL, et al. Among authors: busacca s. Eur J Cancer. 2012 May;48(7):1096-107. doi: 10.1016/j.ejca.2011.11.009. Epub 2011 Dec 10. Eur J Cancer. 2012. PMID: 22154545

2

Preliminary data suggestive of a novel translational approach to mesothelioma treatment: imatinib mesylate with gemcitabine or pemetrexed.

Bertino P, Porta C, Barbone D, Germano S, Busacca S, Pinato S, Tassi G, Favoni R, Gaudino G, Mutti L. Bertino P, et al. Among authors: busacca s. Thorax. 2007 Aug;62(8):690-5. doi: 10.1136/thx.2006.069872. Epub 2007 Feb 20. Thorax. 2007. PMID: 17311837 Free PMC article.

3

MicroRNA regulation of core apoptosis pathways in cancer.

Lima RT, Busacca S, Almeida GM, Gaudino G, Fennell DA, Vasconcelos MH. Lima RT, et al. Among authors: busacca s. Eur J Cancer. 2011 Jan;47(2):163-74. doi: 10.1016/j.ejca.2010.11.005. Epub 2010 Dec 8. Eur J Cancer. 2011. PMID: 21145728 Review.

4

BRCA1 is an essential mediator of vinorelbine-induced apoptosis in mesothelioma.

Busacca S, Sheaff M, Arthur K, Gray SG, O'Byrne KJ, Richard DJ, Soltermann A, Opitz I, Pass H, Harkin DP, Quinn JE, Fennell DA. Busacca S, et al. J Pathol. 2012 Jun;227(2):200-8. doi: 10.1002/path.3979. Epub 2012 Mar 19. J Pathol. 2012. PMID: 22190288

5

Response to chemotherapy is predictive in relation to longer overall survival in an individual patient combined-analysis with pleural mesothelioma.

Blayney JK, Ceresoli GL, Castagneto B, O'Brien ME, Hasan B, Sylvester R, Rudd R, Steele J, Busacca S, Porta C, Mutti L, O'Byrne KJ, Scullin P, Gaafar R, Baas P, Van Meerbeeck J, Fennell DA. Blayney JK, et al. Among authors: busacca s. Eur J Cancer. 2012 Nov;48(16):2983-92. doi: 10.1016/j.ejca.2012.05.018. Epub 2012 Jun 15. Eur J Cancer. 2012. PMID: 22704893

6

Phase II clinical trial of first or second-line treatment with bortezomib in patients with malignant pleural mesothelioma.

Fennell DA, McDowell C, Busacca S, Webb G, Moulton B, Cakana A, O'Byrne KJ, Meerbeeck JV, Donnellan P, McCaffrey J, Baas P. Fennell DA, et al. Among authors: busacca s. J Thorac Oncol. 2012 Sep;7(9):1466-70. doi: 10.1097/JTO.0b013e318260dfb9. J Thorac Oncol. 2012. PMID: 22895144 Free article. Clinical Trial.

7

Acquired differential regulation of caspase-8 in cisplatin-resistant non-small-cell lung cancer.

Paul I, Chacko AD, Stasik I, Busacca S, Crawford N, McCoy F, McTavish N, Wilson B, Barr M, O'Byrne KJ, Longley DB, Fennell DA. Paul I, et al. Among authors: busacca s. Cell Death Dis. 2012 Dec 20;3(12):e449. doi: 10.1038/cddis.2012.186. Cell Death Dis. 2012. PMID: 23254292 Free PMC article.

8

Vorinostat eliminates multicellular resistance of mesothelioma 3D spheroids via restoration of Noxa expression.

Barbone D, Cheung P, Battula S, Busacca S, Gray SG, Longley DB, Bueno R, Sugarbaker DJ, Fennell DA, Broaddus VC. Barbone D, et al. Among authors: busacca s. PLoS One. 2012;7(12):e52753. doi: 10.1371/journal.pone.0052753. Epub 2012 Dec 26. PLoS One. 2012. PMID: 23300762 Free PMC article.

9

BAK and NOXA are critical determinants of mitochondrial apoptosis induced by bortezomib in mesothelioma.

Busacca S, Chacko AD, Klabatsa A, Arthur K, Sheaff M, Barbone D, Mutti L, Gunasekharan VK, Gorski JJ, El-Tanani M, Broaddus VC, Gaudino G, Fennell DA. Busacca S, et al. PLoS One. 2013 Jun 7;8(6):e65489. doi: 10.1371/journal.pone.0065489. Print 2013. PLoS One. 2013. PMID: 23762382 Free PMC article.

10

Resistance to HSP90 inhibition involving loss of MCL1 addiction.

Busacca S, Law EW, Powley IR, Proia DA, Sequeira M, Le Quesne J, Klabatsa A, Edwards JM, Matchett KB, Luo JL, Pringle JH, El-Tanani M, MacFarlane M, Fennell DA. Busacca S, et al. Oncogene. 2016 Mar 24;35(12):1483-92. doi: 10.1038/onc.2015.213. Epub 2015 Jun 22. Oncogene. 2016. PMID: 26096930 Free PMC article.

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