Wrana JL - Search Results

1

Coordinating developmental signaling: novel roles for the Hippo pathway.

Varelas X, Wrana JL. Varelas X, et al. Among authors: wrana jl. Trends Cell Biol. 2012 Feb;22(2):88-96. doi: 10.1016/j.tcb.2011.10.002. Epub 2011 Dec 5. Trends Cell Biol. 2012. PMID: 22153608 Review.

2

TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal.

Varelas X, Sakuma R, Samavarchi-Tehrani P, Peerani R, Rao BM, Dembowy J, Yaffe MB, Zandstra PW, Wrana JL. Varelas X, et al. Among authors: wrana jl. Nat Cell Biol. 2008 Jul;10(7):837-48. doi: 10.1038/ncb1748. Epub 2008 Jun 22. Nat Cell Biol. 2008. PMID: 18568018

3

Phosphorylation of the tumor suppressor fat is regulated by its ligand Dachsous and the kinase discs overgrown.

Sopko R, Silva E, Clayton L, Gardano L, Barrios-Rodiles M, Wrana J, Varelas X, Arbouzova NI, Shaw S, Saburi S, Matakatsu H, Blair S, McNeill H. Sopko R, et al. Curr Biol. 2009 Jul 14;19(13):1112-7. doi: 10.1016/j.cub.2009.05.049. Epub 2009 Jun 18. Curr Biol. 2009. PMID: 19540118 Free PMC article.

4

The ubiquitin binding region of the Smurf HECT domain facilitates polyubiquitylation and binding of ubiquitylated substrates.

Ogunjimi AA, Wiesner S, Briant DJ, Varelas X, Sicheri F, Forman-Kay J, Wrana JL. Ogunjimi AA, et al. Among authors: wrana jl. J Biol Chem. 2010 Feb 26;285(9):6308-15. doi: 10.1074/jbc.M109.044537. Epub 2009 Dec 21. J Biol Chem. 2010. PMID: 20026602 Free PMC article.

5

The Hippo pathway regulates Wnt/beta-catenin signaling.

Varelas X, Miller BW, Sopko R, Song S, Gregorieff A, Fellouse FA, Sakuma R, Pawson T, Hunziker W, McNeill H, Wrana JL, Attisano L. Varelas X, et al. Among authors: wrana jl. Dev Cell. 2010 Apr 20;18(4):579-91. doi: 10.1016/j.devcel.2010.03.007. Dev Cell. 2010. PMID: 20412773 Free article.

6

The Crumbs complex couples cell density sensing to Hippo-dependent control of the TGF-β-SMAD pathway.

Varelas X, Samavarchi-Tehrani P, Narimatsu M, Weiss A, Cockburn K, Larsen BG, Rossant J, Wrana JL. Varelas X, et al. Among authors: wrana jl. Dev Cell. 2010 Dec 14;19(6):831-44. doi: 10.1016/j.devcel.2010.11.012. Dev Cell. 2010. PMID: 21145499 Free article.

7

An allosteric inhibitor of the human Cdc34 ubiquitin-conjugating enzyme.

Ceccarelli DF, Tang X, Pelletier B, Orlicky S, Xie W, Plantevin V, Neculai D, Chou YC, Ogunjimi A, Al-Hakim A, Varelas X, Koszela J, Wasney GA, Vedadi M, Dhe-Paganon S, Cox S, Xu S, Lopez-Girona A, Mercurio F, Wrana J, Durocher D, Meloche S, Webb DR, Tyers M, Sicheri F. Ceccarelli DF, et al. Cell. 2011 Jun 24;145(7):1075-87. doi: 10.1016/j.cell.2011.05.039. Epub 2011 Jun 16. Cell. 2011. PMID: 21683433 Free article.

8

Switch enhancers interpret TGF-β and Hippo signaling to control cell fate in human embryonic stem cells.

Beyer TA, Weiss A, Khomchuk Y, Huang K, Ogunjimi AA, Varelas X, Wrana JL. Beyer TA, et al. Among authors: wrana jl. Cell Rep. 2013 Dec 26;5(6):1611-24. doi: 10.1016/j.celrep.2013.11.021. Epub 2013 Dec 12. Cell Rep. 2013. PMID: 24332857 Free article.

9

Distinct polarity cues direct Taz/Yap and TGFβ receptor localization to differentially control TGFβ-induced Smad signaling.

Narimatsu M, Samavarchi-Tehrani P, Varelas X, Wrana JL. Narimatsu M, et al. Among authors: wrana jl. Dev Cell. 2015 Mar 9;32(5):652-6. doi: 10.1016/j.devcel.2015.02.019. Dev Cell. 2015. PMID: 25758863 Free article.

10

Hippo signalling in intestinal regeneration and cancer.

Gregorieff A, Wrana JL. Gregorieff A, et al. Among authors: wrana jl. Curr Opin Cell Biol. 2017 Oct;48:17-25. doi: 10.1016/j.ceb.2017.04.005. Epub 2017 May 18. Curr Opin Cell Biol. 2017. PMID: 28527754 Review.

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