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Page 1
Recombinant IgE antibodies for passive immunotherapy of solid tumours: from concept towards clinical application.
Karagiannis SN, Josephs DH, Karagiannis P, Gilbert AE, Saul L, Rudman SM, Dodev T, Koers A, Blower PJ, Corrigan C, Beavil AJ, Spicer JF, Nestle FO, Gould HJ. Karagiannis SN, et al. Among authors: blower pj. Cancer Immunol Immunother. 2012 Sep;61(9):1547-64. doi: 10.1007/s00262-011-1162-8. Epub 2011 Dec 3. Cancer Immunol Immunother. 2012. PMID: 22139135 Free PMC article. Review.
Monitoring the systemic human memory B cell compartment of melanoma patients for anti-tumor IgG antibodies.
Gilbert AE, Karagiannis P, Dodev T, Koers A, Lacy K, Josephs DH, Takhar P, Geh JL, Healy C, Harries M, Acland KM, Rudman SM, Beavil RL, Blower PJ, Beavil AJ, Gould HJ, Spicer J, Nestle FO, Karagiannis SN. Gilbert AE, et al. Among authors: blower pj. PLoS One. 2011 Apr 29;6(4):e19330. doi: 10.1371/journal.pone.0019330. PLoS One. 2011. PMID: 21559411 Free PMC article.
Harnessing engineered antibodies of the IgE class to combat malignancy: initial assessment of FcɛRI-mediated basophil activation by a tumour-specific IgE antibody to evaluate the risk of type I hypersensitivity.
Rudman SM, Josephs DH, Cambrook H, Karagiannis P, Gilbert AE, Dodev T, Hunt J, Koers A, Montes A, Taams L, Canevari S, Figini M, Blower PJ, Beavil AJ, Nicodemus CF, Corrigan C, Kaye SB, Nestle FO, Gould HJ, Spicer JF, Karagiannis SN. Rudman SM, et al. Among authors: blower pj. Clin Exp Allergy. 2011 Oct;41(10):1400-13. doi: 10.1111/j.1365-2222.2011.03770.x. Epub 2011 May 16. Clin Exp Allergy. 2011. PMID: 21569129
In vivo SPECT reporter gene imaging of regulatory T cells.
Sharif-Paghaleh E, Sunassee K, Tavaré R, Ratnasothy K, Koers A, Ali N, Alhabbab R, Blower PJ, Lechler RI, Smyth LA, Mullen GE, Lombardi G. Sharif-Paghaleh E, et al. Among authors: blower pj. PLoS One. 2011;6(10):e25857. doi: 10.1371/journal.pone.0025857. Epub 2011 Oct 17. PLoS One. 2011. PMID: 22043296 Free PMC article.
IgG4 subclass antibodies impair antitumor immunity in melanoma.
Karagiannis P, Gilbert AE, Josephs DH, Ali N, Dodev T, Saul L, Correa I, Roberts L, Beddowes E, Koers A, Hobbs C, Ferreira S, Geh JL, Healy C, Harries M, Acland KM, Blower PJ, Mitchell T, Fear DJ, Spicer JF, Lacy KE, Nestle FO, Karagiannis SN. Karagiannis P, et al. Among authors: blower pj. J Clin Invest. 2013 Apr;123(4):1457-74. doi: 10.1172/JCI65579. J Clin Invest. 2013. PMID: 23454746 Free PMC article.
Real-time differential tracking of human neutrophil and eosinophil migration in vivo.
Lukawska JJ, Livieratos L, Sawyer BM, Lee T, O'Doherty M, Blower PJ, Kofi M, Ballinger JR, Corrigan CJ, Gnanasegaran G, Sharif-Paghaleh E, Mullen GE. Lukawska JJ, et al. Among authors: blower pj. J Allergy Clin Immunol. 2014 Jan;133(1):233-9.e1. doi: 10.1016/j.jaci.2013.06.031. Epub 2013 Aug 13. J Allergy Clin Immunol. 2014. PMID: 23953710
Imaging Inflammation in Asthma: Real Time, Differential Tracking of Human Neutrophil and Eosinophil Migration in Allergen Challenged, Atopic Asthmatics in Vivo.
Lukawska JJ, Livieratos L, Sawyer BM, Lee T, O'Doherty M, Blower PJ, Kofi M, Ballinger JR, Corrigan CJ, Gnanasegaran G, Sharif-Paghaleh E, Mullen GE. Lukawska JJ, et al. Among authors: blower pj. EBioMedicine. 2014 Oct 28;1(2-3):173-80. doi: 10.1016/j.ebiom.2014.10.014. eCollection 2014 Dec. EBioMedicine. 2014. PMID: 26137523 Free PMC article.
Anti-Folate Receptor-α IgE but not IgG Recruits Macrophages to Attack Tumors via TNFα/MCP-1 Signaling.
Josephs DH, Bax HJ, Dodev T, Georgouli M, Nakamura M, Pellizzari G, Saul L, Karagiannis P, Cheung A, Herraiz C, Ilieva KM, Correa I, Fittall M, Crescioli S, Gazinska P, Woodman N, Mele S, Chiaruttini G, Gilbert AE, Koers A, Bracher M, Selkirk C, Lentfer H, Barton C, Lever E, Muirhead G, Tsoka S, Canevari S, Figini M, Montes A, Downes N, Dombrowicz D, Corrigan CJ, Beavil AJ, Nestle FO, Jones PS, Gould HJ, Sanz-Moreno V, Blower PJ, Spicer JF, Karagiannis SN. Josephs DH, et al. Among authors: blower pj. Cancer Res. 2017 Mar 1;77(5):1127-1141. doi: 10.1158/0008-5472.CAN-16-1829. Epub 2017 Jan 17. Cancer Res. 2017. PMID: 28096174 Free PMC article.
An immunologically relevant rodent model demonstrates safety of therapy using a tumour-specific IgE.
Josephs DH, Nakamura M, Bax HJ, Dodev TS, Muirhead G, Saul L, Karagiannis P, Ilieva KM, Crescioli S, Gazinska P, Woodman N, Lombardelli C, Kareemaghay S, Selkirk C, Lentfer H, Barton C, Canevari S, Figini M, Downes N, Dombrowicz D, Corrigan CJ, Nestle FO, Jones PS, Gould HJ, Blower PJ, Tsoka S, Spicer JF, Karagiannis SN. Josephs DH, et al. Among authors: blower pj. Allergy. 2018 Dec;73(12):2328-2341. doi: 10.1111/all.13455. Epub 2018 Oct 8. Allergy. 2018. PMID: 29654623 Free PMC article.
205 results