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Inhibition of tumor-associated αvβ3 integrin regulates the angiogenic switch by enhancing expression of IGFBP-4 leading to reduced melanoma growth and angiogenesis in vivo.
Contois LW, Akalu A, Caron JM, Tweedie E, Cretu A, Henderson T, Liaw L, Friesel R, Vary C, Brooks PC. Contois LW, et al. Among authors: caron jm. Angiogenesis. 2015 Jan;18(1):31-46. doi: 10.1007/s10456-014-9445-2. Epub 2014 Sep 24. Angiogenesis. 2015. PMID: 25249331 Free PMC article.
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