VTX-2337 is a novel TLR8 agonist that activates NK cells and augments ADCC.
Lu H, Dietsch GN, Matthews MA, Yang Y, Ghanekar S, Inokuma M, Suni M, Maino VC, Henderson KE, Howbert JJ, Disis ML, Hershberg RM.
Lu H, et al. Among authors: disis ml.
Clin Cancer Res. 2012 Jan 15;18(2):499-509. doi: 10.1158/1078-0432.CCR-11-1625. Epub 2011 Nov 29.
Clin Cancer Res. 2012.
PMID: 22128302