Boyer TG - Search Results

1

Lethal mitochondrial cardiomyopathy in a hypomorphic Med30 mouse mutant is ameliorated by ketogenic diet.

Krebs P, Fan W, Chen YH, Tobita K, Downes MR, Wood MR, Sun L, Li X, Xia Y, Ding N, Spaeth JM, Moresco EM, Boyer TG, Lo CW, Yen J, Evans RM, Beutler B. Krebs P, et al. Among authors: boyer tg. Proc Natl Acad Sci U S A. 2011 Dec 6;108(49):19678-82. doi: 10.1073/pnas.1117835108. Epub 2011 Nov 21. Proc Natl Acad Sci U S A. 2011. PMID: 22106289 Free PMC article.

2

MED12 mutations link intellectual disability syndromes with dysregulated GLI3-dependent Sonic Hedgehog signaling.

Zhou H, Spaeth JM, Kim NH, Xu X, Friez MJ, Schwartz CE, Boyer TG. Zhou H, et al. Among authors: boyer tg. Proc Natl Acad Sci U S A. 2012 Nov 27;109(48):19763-8. doi: 10.1073/pnas.1121120109. Epub 2012 Oct 22. Proc Natl Acad Sci U S A. 2012. PMID: 23091001 Free PMC article.

3

Mediator and human disease.

Spaeth JM, Kim NH, Boyer TG. Spaeth JM, et al. Among authors: boyer tg. Semin Cell Dev Biol. 2011 Sep;22(7):776-87. doi: 10.1016/j.semcdb.2011.07.024. Epub 2011 Aug 4. Semin Cell Dev Biol. 2011. PMID: 21840410 Free PMC article. Review.

4

Oncogenic exon 2 mutations in Mediator subunit MED12 disrupt allosteric activation of cyclin C-CDK8/19.

Park MJ, Shen H, Spaeth JM, Tolvanen JH, Failor C, Knudtson JF, McLaughlin J, Halder SK, Yang Q, Bulun SE, Al-Hendy A, Schenken RS, Aaltonen LA, Boyer TG. Park MJ, et al. Among authors: boyer tg. J Biol Chem. 2018 Mar 30;293(13):4870-4882. doi: 10.1074/jbc.RA118.001725. Epub 2018 Feb 13. J Biol Chem. 2018. PMID: 29440396 Free PMC article.

5

MED19 and MED26 are synergistic functional targets of the RE1 silencing transcription factor in epigenetic silencing of neuronal gene expression.

Ding N, Tomomori-Sato C, Sato S, Conaway RC, Conaway JW, Boyer TG. Ding N, et al. Among authors: boyer tg. J Biol Chem. 2009 Jan 30;284(5):2648-2656. doi: 10.1074/jbc.M806514200. Epub 2008 Dec 2. J Biol Chem. 2009. PMID: 19049968 Free PMC article.

6

Uterine leiomyoma-linked MED12 mutations disrupt mediator-associated CDK activity.

Turunen M, Spaeth JM, Keskitalo S, Park MJ, Kivioja T, Clark AD, Mäkinen N, Gao F, Palin K, Nurkkala H, Vähärautio A, Aavikko M, Kämpjärvi K, Vahteristo P, Kim CA, Aaltonen LA, Varjosalo M, Taipale J, Boyer TG. Turunen M, et al. Among authors: boyer tg. Cell Rep. 2014 May 8;7(3):654-60. doi: 10.1016/j.celrep.2014.03.047. Epub 2014 Apr 18. Cell Rep. 2014. PMID: 24746821 Free PMC article.

7

Mediator links epigenetic silencing of neuronal gene expression with x-linked mental retardation.

Ding N, Zhou H, Esteve PO, Chin HG, Kim S, Xu X, Joseph SM, Friez MJ, Schwartz CE, Pradhan S, Boyer TG. Ding N, et al. Among authors: boyer tg. Mol Cell. 2008 Aug 8;31(3):347-59. doi: 10.1016/j.molcel.2008.05.023. Mol Cell. 2008. PMID: 18691967 Free PMC article.

8

Mediator complex proximal Tail subunit MED30 is critical for Mediator core stability and cardiomyocyte transcriptional network.

Tan C, Zhu S, Chen Z, Liu C, Li YE, Zhu M, Zhang Z, Zhang Z, Zhang L, Gu Y, Liang Z, Boyer TG, Ouyang K, Evans SM, Fang X. Tan C, et al. Among authors: boyer tg. PLoS Genet. 2021 Sep 10;17(9):e1009785. doi: 10.1371/journal.pgen.1009785. eCollection 2021 Sep. PLoS Genet. 2021. PMID: 34506481 Free PMC article.

9

BRCA1 mediates ligand-independent transcriptional repression of the estrogen receptor.

Zheng L, Annab LA, Afshari CA, Lee WH, Boyer TG. Zheng L, et al. Among authors: boyer tg. Proc Natl Acad Sci U S A. 2001 Aug 14;98(17):9587-92. doi: 10.1073/pnas.171174298. Epub 2001 Aug 7. Proc Natl Acad Sci U S A. 2001. PMID: 11493692 Free PMC article.

10

Mutations in Exon 1 highlight the role of MED12 in uterine leiomyomas.

Kämpjärvi K, Park MJ, Mehine M, Kim NH, Clark AD, Bützow R, Böhling T, Böhm J, Mecklin JP, Järvinen H, Tomlinson IP, van der Spuy ZM, Sjöberg J, Boyer TG, Vahteristo P. Kämpjärvi K, et al. Among authors: boyer tg. Hum Mutat. 2014 Sep;35(9):1136-41. doi: 10.1002/humu.22612. Epub 2014 Jul 21. Hum Mutat. 2014. PMID: 24980722

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