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Anticancer activity of methyl-substituted oxaliplatin analogs.
Jungwirth U, Xanthos DN, Gojo J, Bytzek AK, Körner W, Heffeter P, Abramkin SA, Jakupec MA, Hartinger CG, Windberger U, Galanski M, Keppler BK, Berger W. Jungwirth U, et al. Mol Pharmacol. 2012 May;81(5):719-28. doi: 10.1124/mol.111.077321. Epub 2012 Feb 13. Mol Pharmacol. 2012. PMID: 22331606 Free PMC article.
Triapine-mediated ABCB1 induction via PKC induces widespread therapy unresponsiveness but is not underlying acquired triapine resistance.
Miklos W, Pelivan K, Kowol CR, Pirker C, Dornetshuber-Fleiss R, Spitzwieser M, Englinger B, van Schoonhoven S, Cichna-Markl M, Koellensperger G, Keppler BK, Berger W, Heffeter P. Miklos W, et al. Among authors: keppler bk. Cancer Lett. 2015 May 28;361(1):112-20. doi: 10.1016/j.canlet.2015.02.049. Epub 2015 Mar 5. Cancer Lett. 2015. PMID: 25749419
Sensitivity towards the GRP78 inhibitor KP1339/IT-139 is characterized by apoptosis induction via caspase 8 upon disruption of ER homeostasis.
Schoenhacker-Alte B, Mohr T, Pirker C, Kryeziu K, Kuhn PS, Buck A, Hofmann T, Gerner C, Hermann G, Koellensperger G, Keppler BK, Berger W, Heffeter P. Schoenhacker-Alte B, et al. Among authors: keppler bk. Cancer Lett. 2017 Sep 28;404:79-88. doi: 10.1016/j.canlet.2017.07.009. Epub 2017 Jul 14. Cancer Lett. 2017. PMID: 28716523
Resistance against novel anticancer metal compounds: differences and similarities.
Heffeter P, Jungwirth U, Jakupec M, Hartinger C, Galanski MS, Elbling L, Micksche M, Keppler B, Berger W. Heffeter P, et al. Among authors: keppler b. Drug Resist Updat. 2008 Feb-Apr;11(1-2):1-16. doi: 10.1016/j.drup.2008.02.002. Epub 2008 Apr 3. Drug Resist Updat. 2008. PMID: 18394950 Review.
516 results