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Page 1
Murine double minute 2 regulates Hu antigen R stability in human liver and colon cancer through NEDDylation.
Embade N, Fernández-Ramos D, Varela-Rey M, Beraza N, Sini M, Gutiérrez de Juan V, Woodhoo A, Martínez-López N, Rodríguez-Iruretagoyena B, Bustamante FJ, de la Hoz AB, Carracedo A, Xirodimas DP, Rodríguez MS, Lu SC, Mato JM, Martínez-Chantar ML. Embade N, et al. Hepatology. 2012 Apr;55(4):1237-48. doi: 10.1002/hep.24795. Epub 2012 Mar 1. Hepatology. 2012. PMID: 22095636 Free PMC article.
S-adenosylmethionine and proliferation: new pathways, new targets.
Martínez-López N, Varela-Rey M, Ariz U, Embade N, Vazquez-Chantada M, Fernandez-Ramos D, Gomez-Santos L, Lu SC, Mato JM, Martinez-Chantar ML. Martínez-López N, et al. Biochem Soc Trans. 2008 Oct;36(Pt 5):848-52. doi: 10.1042/BST0360848. Biochem Soc Trans. 2008. PMID: 18793149
Evidence for LKB1/AMP-activated protein kinase/ endothelial nitric oxide synthase cascade regulated by hepatocyte growth factor, S-adenosylmethionine, and nitric oxide in hepatocyte proliferation.
Vázquez-Chantada M, Ariz U, Varela-Rey M, Embade N, Martínez-Lopez N, Fernández-Ramos D, Gómez-Santos L, Lamas S, Lu SC, Martínez-Chantar ML, Mato JM. Vázquez-Chantada M, et al. Hepatology. 2009 Feb;49(2):608-17. doi: 10.1002/hep.22660. Hepatology. 2009. PMID: 19177591 Free PMC article.
Impaired liver regeneration in mice lacking glycine N-methyltransferase.
Varela-Rey M, Fernández-Ramos D, Martínez-López N, Embade N, Gómez-Santos L, Beraza N, Vázquez-Chantada M, Rodríguez J, Luka Z, Wagner C, Lu SC, Martínez-Chantar ML, Mato JM. Varela-Rey M, et al. Hepatology. 2009 Aug;50(2):443-52. doi: 10.1002/hep.23033. Hepatology. 2009. PMID: 19582817 Free PMC article.
HuR/methyl-HuR and AUF1 regulate the MAT expressed during liver proliferation, differentiation, and carcinogenesis.
Vázquez-Chantada M, Fernández-Ramos D, Embade N, Martínez-Lopez N, Varela-Rey M, Woodhoo A, Luka Z, Wagner C, Anglim PP, Finnell RH, Caballería J, Laird-Offringa IA, Gorospe M, Lu SC, Mato JM, Martínez-Chantar ML. Vázquez-Chantada M, et al. Gastroenterology. 2010 May;138(5):1943-53. doi: 10.1053/j.gastro.2010.01.032. Epub 2010 Jan 25. Gastroenterology. 2010. PMID: 20102719 Free PMC article.
Fatty liver and fibrosis in glycine N-methyltransferase knockout mice is prevented by nicotinamide.
Varela-Rey M, Martínez-López N, Fernández-Ramos D, Embade N, Calvisi DF, Woodhoo A, Rodríguez J, Fraga MF, Julve J, Rodríguez-Millán E, Frades I, Torres L, Luka Z, Wagner C, Esteller M, Lu SC, Martínez-Chantar ML, Mato JM. Varela-Rey M, et al. Hepatology. 2010 Jul;52(1):105-14. doi: 10.1002/hep.23639. Hepatology. 2010. PMID: 20578266 Free PMC article.
Activation of LKB1-Akt pathway independent of phosphoinositide 3-kinase plays a critical role in the proliferation of hepatocellular carcinoma from nonalcoholic steatohepatitis.
Martínez-López N, Varela-Rey M, Fernández-Ramos D, Woodhoo A, Vázquez-Chantada M, Embade N, Espinosa-Hevia L, Bustamante FJ, Parada LA, Rodriguez MS, Lu SC, Mato JM, Martínez-Chantar ML. Martínez-López N, et al. Hepatology. 2010 Nov;52(5):1621-31. doi: 10.1002/hep.23860. Hepatology. 2010. PMID: 20815019 Free PMC article.
Human antigen R contributes to hepatic stellate cell activation and liver fibrosis.
Woodhoo A, Iruarrizaga-Lejarreta M, Beraza N, García-Rodríguez JL, Embade N, Fernández-Ramos D, Martínez-López N, Gutiérrez-De Juan V, Arteta B, Caballeria J, Lu SC, Mato JM, Varela-Rey M, Martínez-Chantar ML. Woodhoo A, et al. Hepatology. 2012 Nov;56(5):1870-82. doi: 10.1002/hep.25828. Epub 2012 Oct 9. Hepatology. 2012. PMID: 22576182 Free PMC article.
Hepatoma cells from mice deficient in glycine N-methyltransferase have increased RAS signaling and activation of liver kinase B1.
Martínez-López N, García-Rodríguez JL, Varela-Rey M, Gutiérrez V, Fernández-Ramos D, Beraza N, Aransay AM, Schlangen K, Lozano JJ, Aspichueta P, Luka Z, Wagner C, Evert M, Calvisi DF, Lu SC, Mato JM, Martínez-Chantar ML. Martínez-López N, et al. Gastroenterology. 2012 Sep;143(3):787-798.e13. doi: 10.1053/j.gastro.2012.05.050. Epub 2012 Jun 8. Gastroenterology. 2012. PMID: 22687285 Free PMC article.
Methionine and S-adenosylmethionine levels are critical regulators of PP2A activity modulating lipophagy during steatosis.
Zubiete-Franco I, García-Rodríguez JL, Martínez-Uña M, Martínez-Lopez N, Woodhoo A, Juan VG, Beraza N, Lage-Medina S, Andrade F, Fernandez ML, Aldámiz-Echevarría L, Fernández-Ramos D, Falcon-Perez JM, Lopitz-Otsoa F, Fernandez-Tussy P, Barbier-Torres L, Luka Z, Wagner C, García-Monzón C, Lu SC, Aspichueta P, Mato JM, Martínez-Chantar ML, Varela-Rey M. Zubiete-Franco I, et al. J Hepatol. 2016 Feb;64(2):409-418. doi: 10.1016/j.jhep.2015.08.037. Epub 2015 Sep 21. J Hepatol. 2016. PMID: 26394163 Free PMC article.
49 results