Hardingham GE - Search Results

1

Human embryonic stem cell derived astrocytes mediate non-cell-autonomous neuroprotection through endogenous and drug-induced mechanisms.

Gupta K, Patani R, Baxter P, Serio A, Story D, Tsujita T, Hayes JD, Pedersen RA, Hardingham GE, Chandran S. Gupta K, et al. Among authors: hardingham ge. Cell Death Differ. 2012 May;19(5):779-87. doi: 10.1038/cdd.2011.154. Epub 2011 Nov 18. Cell Death Differ. 2012. PMID: 22095276 Free PMC article.

2

Induction of sulfiredoxin expression and reduction of peroxiredoxin hyperoxidation by the neuroprotective Nrf2 activator 3H-1,2-dithiole-3-thione.

Soriano FX, Léveillé F, Papadia S, Higgins LG, Varley J, Baxter P, Hayes JD, Hardingham GE. Soriano FX, et al. Among authors: hardingham ge. J Neurochem. 2008 Oct;107(2):533-43. doi: 10.1111/j.1471-4159.2008.05648.x. Epub 2008 Sep 16. J Neurochem. 2008. PMID: 18761713 Free PMC article.

3

Specific targeting of pro-death NMDA receptor signals with differing reliance on the NR2B PDZ ligand.

Soriano FX, Martel MA, Papadia S, Vaslin A, Baxter P, Rickman C, Forder J, Tymianski M, Duncan R, Aarts M, Clarke P, Wyllie DJ, Hardingham GE. Soriano FX, et al. Among authors: hardingham ge. J Neurosci. 2008 Oct 15;28(42):10696-710. doi: 10.1523/JNEUROSCI.1207-08.2008. J Neurosci. 2008. PMID: 18923045 Free PMC article.

4

Inhibiting pro-death NMDA receptor signaling dependent on the NR2 PDZ ligand may not affect synaptic function or synaptic NMDA receptor signaling to gene expression.

Martel MA, Soriano FX, Baxter P, Rickman C, Duncan R, Wyllie DJ, Hardingham GE. Martel MA, et al. Among authors: hardingham ge. Channels (Austin). 2009 Jan-Feb;3(1):12-5. doi: 10.4161/chan.3.1.7864. Epub 2009 Jan 16. Channels (Austin). 2009. PMID: 19221512 Free article.

5

Transcriptional regulation of the AP-1 and Nrf2 target gene sulfiredoxin.

Soriano FX, Baxter P, Murray LM, Sporn MB, Gillingwater TH, Hardingham GE. Soriano FX, et al. Among authors: hardingham ge. Mol Cells. 2009 Mar 31;27(3):279-82. doi: 10.1007/s10059-009-0050-y. Epub 2009 Mar 19. Mol Cells. 2009. PMID: 19326073 Free PMC article. Review.

6

Activin/Nodal inhibition alone accelerates highly efficient neural conversion from human embryonic stem cells and imposes a caudal positional identity.

Patani R, Compston A, Puddifoot CA, Wyllie DJ, Hardingham GE, Allen ND, Chandran S. Patani R, et al. Among authors: hardingham ge. PLoS One. 2009 Oct 6;4(10):e7327. doi: 10.1371/journal.pone.0007327. PLoS One. 2009. PMID: 19806200 Free PMC article.

7

Human embryonic stem cell-derived neurons as a tool for studying neuroprotection and neurodegeneration.

Hardingham GE, Patani R, Baxter P, Wyllie DJ, Chandran S. Hardingham GE, et al. Mol Neurobiol. 2010 Aug;42(1):97-102. doi: 10.1007/s12035-010-8136-2. Epub 2010 Apr 30. Mol Neurobiol. 2010. PMID: 20431962 Free PMC article.

8

Mild oxidative stress activates Nrf2 in astrocytes, which contributes to neuroprotective ischemic preconditioning.

Bell KF, Al-Mubarak B, Fowler JH, Baxter PS, Gupta K, Tsujita T, Chowdhry S, Patani R, Chandran S, Horsburgh K, Hayes JD, Hardingham GE. Bell KF, et al. Among authors: hardingham ge. Proc Natl Acad Sci U S A. 2011 Jan 4;108(1):E1-2; author reply E3-4. doi: 10.1073/iti0111108. Epub 2010 Dec 21. Proc Natl Acad Sci U S A. 2011. PMID: 21177433 Free PMC article. No abstract available.

9

Retinoid-independent motor neurogenesis from human embryonic stem cells reveals a medial columnar ground state.

Patani R, Hollins AJ, Wishart TM, Puddifoot CA, Alvarez S, de Lera AR, Wyllie DJ, Compston DA, Pedersen RA, Gillingwater TH, Hardingham GE, Allen ND, Chandran S. Patani R, et al. Among authors: hardingham ge. Nat Commun. 2011;2:214. doi: 10.1038/ncomms1216. Nat Commun. 2011. PMID: 21364553 Free PMC article.

10

Pituitary adenylate cyclase-activating peptide induces long-lasting neuroprotection through the induction of activity-dependent signaling via the cyclic AMP response element-binding protein-regulated transcription co-activator 1.

Baxter PS, Martel MA, McMahon A, Kind PC, Hardingham GE. Baxter PS, et al. Among authors: hardingham ge. J Neurochem. 2011 Aug;118(3):365-78. doi: 10.1111/j.1471-4159.2011.07330.x. Epub 2011 Jun 17. J Neurochem. 2011. PMID: 21623792 Free PMC article.

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