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2,197 results

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Optimal Combination of Effective ANtihypertensives (OCEAN) study: a prospective, randomized, open-label, blinded endpoint trial--rationale, design and results of a pilot study in Japan.
Kageyama S, Ueda S, Mochizuki K, Miyakawa M, Sugawara M, Nakayama M, Ohashi Y, Saito I, Saruta T; OCEAN Study Group. Kageyama S, et al. Among authors: ohashi y. Hypertens Res. 2012 Feb;35(2):221-7. doi: 10.1038/hr.2011.178. Epub 2011 Nov 17. Hypertens Res. 2012. PMID: 22089534 Clinical Trial.
Prevention of cardiovascular events with calcium channel blocker-based combination therapies in patients with hypertension: a randomized controlled trial.
Matsuzaki M, Ogihara T, Umemoto S, Rakugi H, Matsuoka H, Shimada K, Abe K, Suzuki N, Eto T, Higaki J, Ito S, Kamiya A, Kikuchi K, Suzuki H, Tei C, Ohashi Y, Saruta T; Combination Therapy of Hypertension to Prevent Cardiovascular Events Trial Group. Matsuzaki M, et al. Among authors: ohashi y. J Hypertens. 2011 Aug;29(8):1649-59. doi: 10.1097/HJH.0b013e328348345d. J Hypertens. 2011. PMID: 21610513 Clinical Trial.
Combination therapy for hypertension in the elderly: a sub-analysis of the Combination Therapy of Hypertension to Prevent Cardiovascular Events (COPE) Trial.
Ogihara T, Matsuzaki M, Umemoto S, Rakugi H, Matsuoka H, Shimada K, Higaki J, Ito S, Kamiya A, Suzuki H, Ohashi Y, Shimamoto K, Saruta T; Combination Therapy of Hypertension to Prevent Cardiovascular Events Trial Group. Ogihara T, et al. Among authors: ohashi y. Hypertens Res. 2012 Apr;35(4):441-8. doi: 10.1038/hr.2011.216. Epub 2012 Jan 26. Hypertens Res. 2012. PMID: 22278623 Clinical Trial.
Combination therapy for hypertension in patients with CKD: a subanalysis of the Combination Therapy of Hypertension to Prevent Cardiovascular Events trial.
Rakugi H, Ogihara T, Umemoto S, Matsuzaki M, Matsuoka H, Shimada K, Higaki J, Ito S, Kamiya A, Suzuki H, Ohashi Y, Shimamoto K, Saruta T; Combination Therapy of Hypertension to Prevent Cardiovascular Events Trial Group. Rakugi H, et al. Among authors: ohashi y. Hypertens Res. 2013 Nov;36(11):947-58. doi: 10.1038/hr.2013.63. Epub 2013 Jul 18. Hypertens Res. 2013. PMID: 23864054 Clinical Trial.
Effects of a benidipine-based combination therapy on the risk of stroke according to stroke subtype: the COPE trial.
Umemoto S, Ogihara T, Rakugi H, Matsumoto M, Kitagawa K, Shimada K, Higaki J, Ito S, Suzuki H, Ohashi Y, Saruta T, Matsuzaki M; Combination Therapy of Hypertension to Prevent Cardiovascular. Umemoto S, et al. Among authors: ohashi y. Hypertens Res. 2013 Dec;36(12):1088-95. doi: 10.1038/hr.2013.100. Epub 2013 Aug 29. Hypertens Res. 2013. PMID: 23985703
Effects of calcium channel blocker-based combinations on intra-individual blood pressure variability: post hoc analysis of the COPE trial.
Umemoto S, Ogihara T, Matsuzaki M, Rakugi H, Ohashi Y, Saruta T; Combination Therapy of Hypertension to Prevent Cardiovascular Events COPE Trial Group. Umemoto S, et al. Among authors: ohashi y. Hypertens Res. 2016 Jan;39(1):46-53. doi: 10.1038/hr.2015.104. Epub 2015 Oct 22. Hypertens Res. 2016. PMID: 26490089 Free PMC article. Clinical Trial.
Effects of calcium channel blocker benidipine-based combination therapy on target blood pressure control and cardiovascular outcome: a sub-analysis of the COPE trial.
Umemoto S, Ogihara T, Matsuzaki M, Rakugi H, Ohashi Y, Saruta T; Combination Therapy of Hypertension to Prevent Cardiovascular Events (COPE) Trial Group. Umemoto S, et al. Among authors: ohashi y. Hypertens Res. 2017 Apr;40(4):376-384. doi: 10.1038/hr.2016.158. Epub 2016 Dec 1. Hypertens Res. 2017. PMID: 27904156 Free PMC article. Clinical Trial.
Effects of Calcium-Channel Blocker Benidipine-Based Combination Therapy on Cardiac Events　- Subanalysis of the COPE Trial.
Umemoto S, Ogihara T, Matsuzaki M, Rakugi H, Shimada K, Kawana M, Kario K, Ohashi Y, Saruta T; Combination Therapy of Hypertension to Prevent Cardiovascular Events (COPE) Trial Group. Umemoto S, et al. Among authors: ohashi y. Circ J. 2018 Jan 25;82(2):457-463. doi: 10.1253/circj.CJ-17-0592. Epub 2017 Sep 2. Circ J. 2018. PMID: 28867690 Free article. Clinical Trial.
Effects of an Antihypertensive Combination in Japanese Hypertensive Outpatients Based on the Long-acting Calcium Channel Blocker Benidipine on Vascular and Renal Events: A Sub-analysis of the COPE Trial.
Umemoto S, Ogihara T, Matsuzaki M, Rakugi H, Shimada K, Hayashi K, Makino H, Ohashi Y, Saruta T. Umemoto S, et al. Among authors: ohashi y. Curr Hypertens Rev. 2020;16(3):238-245. doi: 10.2174/1573402116666200129130151. Curr Hypertens Rev. 2020. PMID: 31995012
2,197 results