Loberg R - Search Results

1

Discovery of potent and highly selective thienopyridine Janus kinase 2 inhibitors.

Schenkel LB, Huang X, Cheng A, Deak HL, Doherty E, Emkey R, Gu Y, Gunaydin H, Kim JL, Lee J, Loberg R, Olivieri P, Pistillo J, Tang J, Wan Q, Wang HL, Wang SW, Wells MC, Wu B, Yu V, Liu L, Geuns-Meyer S. Schenkel LB, et al. Among authors: loberg r. J Med Chem. 2011 Dec 22;54(24):8440-50. doi: 10.1021/jm200911r. Epub 2011 Nov 16. J Med Chem. 2011. PMID: 22087750

2

AMG 900, a small-molecule inhibitor of aurora kinases, potentiates the activity of microtubule-targeting agents in human metastatic breast cancer models.

Bush TL, Payton M, Heller S, Chung G, Hanestad K, Rottman JB, Loberg R, Friberg G, Kendall RL, Saffran D, Radinsky R. Bush TL, et al. Among authors: loberg r. Mol Cancer Ther. 2013 Nov;12(11):2356-66. doi: 10.1158/1535-7163.MCT-12-1178. Epub 2013 Aug 29. Mol Cancer Ther. 2013. PMID: 23990115

3

AMG 900, a potent inhibitor of aurora kinases causes pharmacodynamic changes in p-Histone H3 immunoreactivity in human tumor xenografts and proliferating mouse tissues.

Juan G, Bush TL, Ma C, Manoukian R, Chung G, Hawkins JM, Zoog S, Kendall R, Radinsky R, Loberg R, Friberg G, Payton M. Juan G, et al. Among authors: loberg r. J Transl Med. 2014 Nov 4;12:307. doi: 10.1186/s12967-014-0307-x. J Transl Med. 2014. PMID: 25367255 Free PMC article.

4

Targeting CCL2 with systemic delivery of neutralizing antibodies induces prostate cancer tumor regression in vivo.

Loberg RD, Ying C, Craig M, Day LL, Sargent E, Neeley C, Wojno K, Snyder LA, Yan L, Pienta KJ. Loberg RD, et al. Cancer Res. 2007 Oct 1;67(19):9417-24. doi: 10.1158/0008-5472.CAN-07-1286. Cancer Res. 2007. PMID: 17909051

5

A first-in-human study of AMG 208, an oral MET inhibitor, in adult patients with advanced solid tumors.

Hong DS, Rosen P, Lockhart AC, Fu S, Janku F, Kurzrock R, Khan R, Amore B, Caudillo I, Deng H, Hwang YC, Loberg R, Ngarmchamnanrith G, Beaupre DM, Lee P. Hong DS, et al. Among authors: loberg r. Oncotarget. 2015 Jul 30;6(21):18693-706. doi: 10.18632/oncotarget.4472. Oncotarget. 2015. PMID: 26155941 Free PMC article. Clinical Trial.

6

Phase I Study of AMG 337, a Highly Selective Small-molecule MET Inhibitor, in Patients with Advanced Solid Tumors.

Hong DS, LoRusso P, Hamid O, Janku F, Kittaneh M, Catenacci DVT, Chan E, Bekaii-Saab T, Gadgeel SM, Loberg RD, Amore BM, Hwang YC, Tang R, Ngarmchamnanrith G, Kwak EL. Hong DS, et al. Among authors: loberg rd. Clin Cancer Res. 2019 Apr 15;25(8):2403-2413. doi: 10.1158/1078-0432.CCR-18-1341. Epub 2018 Nov 13. Clin Cancer Res. 2019. PMID: 30425090 Free PMC article.

7

Clinical Pharmacology and Translational Aspects of Bispecific Antibodies.

Trivedi A, Stienen S, Zhu M, Li H, Yuraszeck T, Gibbs J, Heath T, Loberg R, Kasichayanula S. Trivedi A, et al. Among authors: loberg r. Clin Transl Sci. 2017 May;10(3):147-162. doi: 10.1111/cts.12459. Epub 2017 Mar 15. Clin Transl Sci. 2017. PMID: 28297195 Free PMC article. Review. No abstract available.

8

The "emigration, migration, and immigration"of prostate cancer.

Pienta KJ, Loberg R. Pienta KJ, et al. Among authors: loberg r. Clin Prostate Cancer. 2005 Jun;4(1):24-30. doi: 10.3816/cgc.2005.n.008. Clin Prostate Cancer. 2005. PMID: 15992458 Review.

9

A destructive cascade mediated by CCL2 facilitates prostate cancer growth in bone.

Li X, Loberg R, Liao J, Ying C, Snyder LA, Pienta KJ, McCauley LK. Li X, et al. Among authors: loberg r. Cancer Res. 2009 Feb 15;69(4):1685-92. doi: 10.1158/0008-5472.CAN-08-2164. Epub 2009 Jan 27. Cancer Res. 2009. PMID: 19176388 Free PMC article.

10

Development of the VCaP androgen-independent model of prostate cancer.

Loberg RD, St John LN, Day LL, Neeley CK, Pienta KJ. Loberg RD, et al. Urol Oncol. 2006 Mar-Apr;24(2):161-8. doi: 10.1016/j.urolonc.2005.11.005. Urol Oncol. 2006. PMID: 16520280 Free PMC article.

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