Lowndes NF - Search Results

1

Eukaryotic DNA damage checkpoint activation in response to double-strand breaks.

Finn K, Lowndes NF, Grenon M. Finn K, et al. Among authors: lowndes nf. Cell Mol Life Sci. 2012 May;69(9):1447-73. doi: 10.1007/s00018-011-0875-3. Epub 2011 Nov 15. Cell Mol Life Sci. 2012. PMID: 22083606 Free PMC article. Review.

2

Site-specific phosphorylation of the DNA damage response mediator rad9 by cyclin-dependent kinases regulates activation of checkpoint kinase 1.

Abreu CM, Kumar R, Hamilton D, Dawdy AW, Creavin K, Eivers S, Finn K, Balsbaugh JL, O'Connor R, Kiely PA, Shabanowitz J, Hunt DF, Grenon M, Lowndes NF. Abreu CM, et al. Among authors: lowndes nf. PLoS Genet. 2013 Apr;9(4):e1003310. doi: 10.1371/journal.pgen.1003310. Epub 2013 Apr 4. PLoS Genet. 2013. PMID: 23593009 Free PMC article.

3

Histone H2A phosphorylation and H3 methylation are required for a novel Rad9 DSB repair function following checkpoint activation.

Toh GW, O'Shaughnessy AM, Jimeno S, Dobbie IM, Grenon M, Maffini S, O'Rorke A, Lowndes NF. Toh GW, et al. Among authors: lowndes nf. DNA Repair (Amst). 2006 Jun 10;5(6):693-703. doi: 10.1016/j.dnarep.2006.03.005. Epub 2006 May 2. DNA Repair (Amst). 2006. PMID: 16650810

4

Multiple approaches to study S. cerevisiae Rad9, a prototypical checkpoint protein.

O'Shaughnessy AM, Grenon M, Gilbert C, Toh GW, Green CM, Lowndes NF. O'Shaughnessy AM, et al. Among authors: lowndes nf. Methods Enzymol. 2006;409:131-50. doi: 10.1016/S0076-6879(05)09008-7. Methods Enzymol. 2006. PMID: 16793399

5

MRN and the race to the break.

Rupnik A, Lowndes NF, Grenon M. Rupnik A, et al. Among authors: lowndes nf. Chromosoma. 2010 Apr;119(2):115-35. doi: 10.1007/s00412-009-0242-4. Epub 2009 Oct 28. Chromosoma. 2010. PMID: 19862546 Review.

6

Regulation of the DNA damage response and gene expression by the Dot1L histone methyltransferase and the 53Bp1 tumour suppressor.

FitzGerald J, Moureau S, Drogaris P, O'Connell E, Abshiru N, Verreault A, Thibault P, Grenon M, Lowndes NF. FitzGerald J, et al. Among authors: lowndes nf. PLoS One. 2011 Feb 24;6(2):e14714. doi: 10.1371/journal.pone.0014714. PLoS One. 2011. PMID: 21383990 Free PMC article.

7

The MRN complex.

Rupnik A, Grenon M, Lowndes N. Rupnik A, et al. Curr Biol. 2008 Jun 3;18(11):R455-7. doi: 10.1016/j.cub.2008.03.040. Curr Biol. 2008. PMID: 18522810 Free article. No abstract available.

8

Double-strand breaks trigger MRX- and Mec1-dependent, but Tel1-independent, checkpoint activation.

Grenon M, Magill CP, Lowndes NF, Jackson SP. Grenon M, et al. Among authors: lowndes nf. FEMS Yeast Res. 2006 Aug;6(5):836-47. doi: 10.1111/j.1567-1364.2006.00076.x. FEMS Yeast Res. 2006. PMID: 16879433

9

Docking onto chromatin via the Saccharomyces cerevisiae Rad9 Tudor domain.

Grenon M, Costelloe T, Jimeno S, O'Shaughnessy A, Fitzgerald J, Zgheib O, Degerth L, Lowndes NF. Grenon M, et al. Among authors: lowndes nf. Yeast. 2007 Feb;24(2):105-19. doi: 10.1002/yea.1441. Yeast. 2007. PMID: 17243194

10

53BP1: function and mechanisms of focal recruitment.

FitzGerald JE, Grenon M, Lowndes NF. FitzGerald JE, et al. Among authors: lowndes nf. Biochem Soc Trans. 2009 Aug;37(Pt 4):897-904. doi: 10.1042/BST0370897. Biochem Soc Trans. 2009. PMID: 19614615 Review.

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