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Targeting pan-resistant bacteria with antibodies to a broadly conserved surface polysaccharide expressed during infection.
Skurnik D, Davis MR Jr, Benedetti D, Moravec KL, Cywes-Bentley C, Roux D, Traficante DC, Walsh RL, Maira-Litràn T, Cassidy SK, Hermos CR, Martin TR, Thakkallapalli EL, Vargas SO, McAdam AJ, Lieberman TD, Kishony R, Lipuma JJ, Pier GB, Goldberg JB, Priebe GP. Skurnik D, et al. J Infect Dis. 2012 Jun;205(11):1709-18. doi: 10.1093/infdis/jis254. Epub 2012 Mar 23. J Infect Dis. 2012. PMID: 22448004 Free PMC article.
Antibody to a conserved antigenic target is protective against diverse prokaryotic and eukaryotic pathogens.
Cywes-Bentley C, Skurnik D, Zaidi T, Roux D, Deoliveira RB, Garrett WS, Lu X, O'Malley J, Kinzel K, Zaidi T, Rey A, Perrin C, Fichorova RN, Kayatani AK, Maira-Litràn T, Gening ML, Tsvetkov YE, Nifantiev NE, Bakaletz LO, Pelton SI, Golenbock DT, Pier GB. Cywes-Bentley C, et al. Among authors: skurnik d. Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):E2209-18. doi: 10.1073/pnas.1303573110. Epub 2013 May 28. Proc Natl Acad Sci U S A. 2013. PMID: 23716675 Free PMC article.
Enhanced in vivo fitness of carbapenem-resistant oprD mutants of Pseudomonas aeruginosa revealed through high-throughput sequencing.
Skurnik D, Roux D, Cattoir V, Danilchanka O, Lu X, Yoder-Himes DR, Han K, Guillard T, Jiang D, Gaultier C, Guerin F, Aschard H, Leclercq R, Mekalanos JJ, Lory S, Pier GB. Skurnik D, et al. Proc Natl Acad Sci U S A. 2013 Dec 17;110(51):20747-52. doi: 10.1073/pnas.1221552110. Epub 2013 Nov 18. Proc Natl Acad Sci U S A. 2013. PMID: 24248354 Free PMC article. Clinical Trial.
Fitness cost of antibiotic susceptibility during bacterial infection.
Roux D, Danilchanka O, Guillard T, Cattoir V, Aschard H, Fu Y, Angoulvant F, Messika J, Ricard JD, Mekalanos JJ, Lory S, Pier GB, Skurnik D. Roux D, et al. Among authors: skurnik d. Sci Transl Med. 2015 Jul 22;7(297):297ra114. doi: 10.1126/scitranslmed.aab1621. Sci Transl Med. 2015. PMID: 26203082
83 results