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Repeated exposure to Aspergillus fumigatus conidia results in CD4+ T cell-dependent and -independent pulmonary arterial remodeling in a mixed Th1/Th2/Th17 microenvironment that requires interleukin-4 (IL-4) and IL-10.
Shreiner AB, Murdock BJ, Sadighi Akha AA, Falkowski NR, Christensen PJ, White ES, Hogaboam CM, Huffnagle GB. Shreiner AB, et al. Among authors: murdock bj. Infect Immun. 2012 Jan;80(1):388-97. doi: 10.1128/IAI.05530-11. Epub 2011 Nov 7. Infect Immun. 2012. PMID: 22064716 Free PMC article.
PAI-1 promotes the accumulation of exudate macrophages and worsens pulmonary fibrosis following type II alveolar epithelial cell injury.
Osterholzer JJ, Christensen PJ, Lama V, Horowitz JC, Hattori N, Subbotina N, Cunningham A, Lin Y, Murdock BJ, Morey RE, Olszewski MA, Lawrence DA, Simon RH, Sisson TH. Osterholzer JJ, et al. Among authors: murdock bj. J Pathol. 2012 Oct;228(2):170-80. doi: 10.1002/path.3992. Epub 2012 Jun 6. J Pathol. 2012. PMID: 22262246 Free PMC article.
24 results