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Sodium pump alpha2 subunits control myogenic tone and blood pressure in mice.
Zhang J, Lee MY, Cavalli M, Chen L, Berra-Romani R, Balke CW, Bianchi G, Ferrari P, Hamlyn JM, Iwamoto T, Lingrel JB, Matteson DR, Wier WG, Blaustein MP. Zhang J, et al. Among authors: chen l. J Physiol. 2005 Nov 15;569(Pt 1):243-56. doi: 10.1113/jphysiol.2005.091801. Epub 2005 Sep 15. J Physiol. 2005. PMID: 16166162 Free PMC article.
How does salt retention raise blood pressure?
Blaustein MP, Zhang J, Chen L, Hamilton BP. Blaustein MP, et al. Among authors: chen l. Am J Physiol Regul Integr Comp Physiol. 2006 Mar;290(3):R514-23. doi: 10.1152/ajpregu.00819.2005. Am J Physiol Regul Integr Comp Physiol. 2006. PMID: 16467498 Free article. Review.
The pump, the exchanger, and endogenous ouabain: signaling mechanisms that link salt retention to hypertension.
Blaustein MP, Zhang J, Chen L, Song H, Raina H, Kinsey SP, Izuka M, Iwamoto T, Kotlikoff MI, Lingrel JB, Philipson KD, Wier WG, Hamlyn JM. Blaustein MP, et al. Among authors: chen l. Hypertension. 2009 Feb;53(2):291-8. doi: 10.1161/HYPERTENSIONAHA.108.119974. Epub 2008 Dec 22. Hypertension. 2009. PMID: 19104005 Free PMC article. Review. No abstract available.
Knockout of Na+/Ca2+ exchanger in smooth muscle attenuates vasoconstriction and L-type Ca2+ channel current and lowers blood pressure.
Zhang J, Ren C, Chen L, Navedo MF, Antos LK, Kinsey SP, Iwamoto T, Philipson KD, Kotlikoff MI, Santana LF, Wier WG, Matteson DR, Blaustein MP. Zhang J, et al. Among authors: chen l. Am J Physiol Heart Circ Physiol. 2010 May;298(5):H1472-83. doi: 10.1152/ajpheart.00964.2009. Epub 2010 Feb 19. Am J Physiol Heart Circ Physiol. 2010. PMID: 20173044 Free PMC article.
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