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The Golgi stacking protein GRASP55 is targeted by the natural compound prodigiosin.
Berning L, Lenz T, Bergmann AK, Poschmann G, Brass HUC, Schlütermann D, Friedrich A, Mendiburo MJ, David C, Akgün S, Pietruszka J, Stühler K, Stork B. Berning L, et al. Among authors: mendiburo mj. Cell Commun Signal. 2023 Oct 5;21(1):275. doi: 10.1186/s12964-023-01275-1. Cell Commun Signal. 2023. PMID: 37798768 Free PMC article.
Fin56-induced ferroptosis is supported by autophagy-mediated GPX4 degradation and functions synergistically with mTOR inhibition to kill bladder cancer cells.
Sun Y, Berleth N, Wu W, Schlütermann D, Deitersen J, Stuhldreier F, Berning L, Friedrich A, Akgün S, Mendiburo MJ, Wesselborg S, Conrad M, Berndt C, Stork B. Sun Y, et al. Among authors: mendiburo mj. Cell Death Dis. 2021 Oct 29;12(11):1028. doi: 10.1038/s41419-021-04306-2. Cell Death Dis. 2021. PMID: 34716292 Free PMC article.
FIP200 controls the TBK1 activation threshold at SQSTM1/p62-positive condensates.
Schlütermann D, Berleth N, Deitersen J, Wallot-Hieke N, Friesen O, Wu W, Stuhldreier F, Sun Y, Berning L, Friedrich A, Mendiburo MJ, Peter C, Wiek C, Hanenberg H, Stefanski A, Stühler K, Stork B. Schlütermann D, et al. Among authors: mendiburo mj. Sci Rep. 2021 Jul 5;11(1):13863. doi: 10.1038/s41598-021-92408-4. Sci Rep. 2021. PMID: 34226595 Free PMC article.
High-throughput screening for natural compound-based autophagy modulators reveals novel chemotherapeutic mode of action for arzanol.
Deitersen J, Berning L, Stuhldreier F, Ceccacci S, Schlütermann D, Friedrich A, Wu W, Sun Y, Böhler P, Berleth N, Mendiburo MJ, Seggewiß S, Anand R, Reichert AS, Monti MC, Proksch P, Stork B. Deitersen J, et al. Among authors: mendiburo mj. Cell Death Dis. 2021 May 31;12(6):560. doi: 10.1038/s41419-021-03830-5. Cell Death Dis. 2021. PMID: 34059630 Free PMC article.
11 results