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Page 1
Phosphorodiamidates as a promising new phosphate prodrug motif for antiviral drug discovery: application to anti-HCV agents.
McGuigan C, Madela K, Aljarah M, Bourdin C, Arrica M, Barrett E, Jones S, Kolykhalov A, Bleiman B, Bryant KD, Ganguly B, Gorovits E, Henson G, Hunley D, Hutchins J, Muhammad J, Obikhod A, Patti J, Walters CR, Wang J, Vernachio J, Ramamurty CV, Battina SK, Chamberlain S. McGuigan C, et al. Among authors: hunley d. J Med Chem. 2011 Dec 22;54(24):8632-45. doi: 10.1021/jm2011673. Epub 2011 Nov 16. J Med Chem. 2011. PMID: 22039920
Phosphoramidate ProTides of 2'-C-methylguanosine as highly potent inhibitors of hepatitis C virus. Study of their in vitro and in vivo properties.
McGuigan C, Gilles A, Madela K, Aljarah M, Holl S, Jones S, Vernachio J, Hutchins J, Ames B, Bryant KD, Gorovits E, Ganguly B, Hunley D, Hall A, Kolykhalov A, Liu Y, Muhammad J, Raja N, Walters R, Wang J, Chamberlain S, Henson G. McGuigan C, et al. Among authors: hunley d. J Med Chem. 2010 Jul 8;53(13):4949-57. doi: 10.1021/jm1003792. J Med Chem. 2010. PMID: 20527890
Synthesis and evaluation against hepatitis C virus of 7-deaza analogues of 2'-C-methyl-6-O-methyl guanosine nucleoside and L-Alanine ester phosphoramidates.
Bourdin C, McGuigan C, Brancale A, Chamberlain S, Vernachio J, Hutchins J, Gorovits E, Kolykhalov A, Muhammad J, Patti J, Henson G, Bleiman B, Bryant KD, Ganguly B, Hunley D, Obikhod A, Walters CR, Wang J, Ramamurty CV, Battina SK, Srivinas Rao C. Bourdin C, et al. Among authors: hunley d. Bioorg Med Chem Lett. 2013 Apr 1;23(7):2260-4. doi: 10.1016/j.bmcl.2012.12.004. Epub 2012 Dec 20. Bioorg Med Chem Lett. 2013. PMID: 23453067
INX-08189, a phosphoramidate prodrug of 6-O-methyl-2'-C-methyl guanosine, is a potent inhibitor of hepatitis C virus replication with excellent pharmacokinetic and pharmacodynamic properties.
Vernachio JH, Bleiman B, Bryant KD, Chamberlain S, Hunley D, Hutchins J, Ames B, Gorovits E, Ganguly B, Hall A, Kolykhalov A, Liu Y, Muhammad J, Raja N, Walters CR, Wang J, Williams K, Patti JM, Henson G, Madela K, Aljarah M, Gilles A, McGuigan C. Vernachio JH, et al. Among authors: hunley d. Antimicrob Agents Chemother. 2011 May;55(5):1843-51. doi: 10.1128/AAC.01335-10. Epub 2011 Feb 28. Antimicrob Agents Chemother. 2011. PMID: 21357300 Free PMC article.
Ultrafast pulse pumping of topological nanospaser.
Hunley DC, Oliaei Motlagh SA, Ghimire R, Apalkov V. Hunley DC, et al. J Phys Condens Matter. 2023 May 9;35(31). doi: 10.1088/1361-648X/acce14. J Phys Condens Matter. 2023. PMID: 37071999
Review of oncological emergencies in small animal patients.
Tumielewicz KL, Hudak D, Kim J, Hunley DW, Murphy LA. Tumielewicz KL, et al. Among authors: hunley dw. Vet Med Sci. 2019 Aug;5(3):271-296. doi: 10.1002/vms3.164. Epub 2019 Mar 21. Vet Med Sci. 2019. PMID: 30900396 Free PMC article. Review.
Memristive switching of single-component metallic nanowires.
Johnson SL, Sundararajan A, Hunley DP, Strachan DR. Johnson SL, et al. Among authors: hunley dp. Nanotechnology. 2010 Mar 26;21(12):125204. doi: 10.1088/0957-4484/21/12/125204. Epub 2010 Mar 5. Nanotechnology. 2010. PMID: 20203360
11 results