Pucci L - Search Results

1

New spirocyclic Δ²-isoxazoline derivatives related to selective agonists of α7 neuronal nicotinic acetylcholine receptors.

Dallanoce C, Frigerio F, Grazioso G, Matera C, Visconti GL, De Amici M, Pucci L, Pistillo F, Fucile S, Gotti C, Clementi F, De Micheli C. Dallanoce C, et al. Among authors: pucci l. Eur J Med Chem. 2011 Dec;46(12):5790-9. doi: 10.1016/j.ejmech.2011.09.028. Epub 2011 Sep 24. Eur J Med Chem. 2011. PMID: 22014558

2

Epiboxidine and novel-related analogues: a convenient synthetic approach and estimation of their affinity at neuronal nicotinic acetylcholine receptor subtypes.

Rizzi L, Dallanoce C, Matera C, Magrone P, Pucci L, Gotti C, Clementi F, De Amici M. Rizzi L, et al. Among authors: pucci l. Bioorg Med Chem Lett. 2008 Aug 15;18(16):4651-4. doi: 10.1016/j.bmcl.2008.07.016. Epub 2008 Jul 10. Bioorg Med Chem Lett. 2008. PMID: 18644719 Free article.

3

Design of novel alpha7-subtype-preferring nicotinic acetylcholine receptor agonists: application of docking and MM-PBSA computational approaches, synthetic and pharmacological studies.

Grazioso G, Pomè DY, Matera C, Frigerio F, Pucci L, Gotti C, Dallanoce C, De Amici M. Grazioso G, et al. Among authors: pucci l. Bioorg Med Chem Lett. 2009 Nov 15;19(22):6353-7. doi: 10.1016/j.bmcl.2009.09.073. Epub 2009 Sep 24. Bioorg Med Chem Lett. 2009. PMID: 19804970

4

Novel tricyclic Delta(2)-isoxazoline and 3-oxo-2-methyl-isoxazolidine derivatives: synthesis and binding affinity at neuronal nicotinic acetylcholine receptor subtypes.

Dallanoce C, Frigerio F, Martelli G, Grazioso G, Matera C, Pomè DY, Pucci L, Clementi F, Gotti C, De Amici M. Dallanoce C, et al. Among authors: pucci l. Bioorg Med Chem. 2010 Jun 15;18(12):4498-508. doi: 10.1016/j.bmc.2010.04.065. Epub 2010 Apr 27. Bioorg Med Chem. 2010. PMID: 20478710

5

Design, synthesis, and pharmacological characterization of novel spirocyclic quinuclidinyl-Δ2-isoxazoline derivatives as potent and selective agonists of α7 nicotinic acetylcholine receptors.

Dallanoce C, Magrone P, Matera C, Frigerio F, Grazioso G, De Amici M, Fucile S, Piccari V, Frydenvang K, Pucci L, Gotti C, Clementi F, De Micheli C. Dallanoce C, et al. Among authors: pucci l. ChemMedChem. 2011 May 2;6(5):889-903. doi: 10.1002/cmdc.201000514. Epub 2011 Mar 1. ChemMedChem. 2011. PMID: 21365765

6

Unichiral 2-(2'-pyrrolidinyl)-1,4-benzodioxanes: the 2R,2'S diastereomer of the N-methyl-7-hydroxy analogue is a potent α4β2- and α6β2-nicotinic acetylcholine receptor partial agonist.

Bolchi C, Gotti C, Binda M, Fumagalli L, Pucci L, Pistillo F, Vistoli G, Valoti E, Pallavicini M. Bolchi C, et al. Among authors: pucci l. J Med Chem. 2011 Nov 10;54(21):7588-601. doi: 10.1021/jm200937t. Epub 2011 Oct 11. J Med Chem. 2011. PMID: 21942635

7

Synthesis and binding affinity at α4β2 and α7 nicotinic acetylcholine receptors of new analogs of epibatidine and epiboxidine containing the 7-azabicyclo[2.2.1]hept-2-ene ring system.

Dallanoce C, Matera C, Pucci L, Gotti C, Clementi F, Amici MD, Micheli CD. Dallanoce C, et al. Among authors: pucci l. Bioorg Med Chem Lett. 2012 Jan 15;22(2):829-32. doi: 10.1016/j.bmcl.2011.12.052. Epub 2011 Dec 16. Bioorg Med Chem Lett. 2012. PMID: 22222032

8

The enantiomers of epiboxidine and of two related analogs: synthesis and estimation of their binding affinity at α4β2 and α7 neuronal nicotinic acetylcholine receptors.

Dallanoce C, Matera C, De Amici M, Rizzi L, Pucci L, Gotti C, Clementi F, De Micheli C. Dallanoce C, et al. Among authors: pucci l. Chirality. 2012 Jul;24(7):543-51. doi: 10.1002/chir.22052. Epub 2012 May 5. Chirality. 2012. PMID: 22566097

9

Bifunctional compounds targeting both D2 and non-α7 nACh receptors: design, synthesis and pharmacological characterization.

Matera C, Pucci L, Fiorentini C, Fucile S, Missale C, Grazioso G, Clementi F, Zoli M, De Amici M, Gotti C, Dallanoce C. Matera C, et al. Among authors: pucci l. Eur J Med Chem. 2015 Aug 28;101:367-83. doi: 10.1016/j.ejmech.2015.06.039. Epub 2015 Jun 20. Eur J Med Chem. 2015. PMID: 26164842

10

Engineering of α-conotoxin MII-derived peptides with increased selectivity for native α6β2* nicotinic acetylcholine receptors.

Pucci L, Grazioso G, Dallanoce C, Rizzi L, De Micheli C, Clementi F, Bertrand S, Bertrand D, Longhi R, De Amici M, Gotti C. Pucci L, et al. FASEB J. 2011 Nov;25(11):3775-89. doi: 10.1096/fj.10-179853. Epub 2011 Jul 21. FASEB J. 2011. PMID: 21778325

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