Chen YH - Search Results

1

Mutations of Gln64 in the HIV-1 gp41 N-terminal heptad repeat render viruses resistant to peptide HIV fusion inhibitors targeting the gp41 pocket.

Yu X, Lu L, Cai L, Tong P, Tan S, Zou P, Meng F, Chen YH, Jiang S. Yu X, et al. Among authors: chen yh. J Virol. 2012 Jan;86(1):589-93. doi: 10.1128/JVI.05066-11. Epub 2011 Oct 19. J Virol. 2012. PMID: 22013063 Free PMC article.

2

Novel recombinant engineered gp41 N-terminal heptad repeat trimers and their potential as anti-HIV-1 therapeutics or microbicides.

Chen X, Lu L, Qi Z, Lu H, Wang J, Yu X, Chen Y, Jiang S. Chen X, et al. J Biol Chem. 2010 Aug 13;285(33):25506-15. doi: 10.1074/jbc.M110.101170. Epub 2010 Jun 10. J Biol Chem. 2010. PMID: 20538590 Free PMC article.

3

Identification of the HIV-1 gp41 core-binding motif in the scaffolding domain of caveolin-1.

Huang JH, Lu L, Lu H, Chen X, Jiang S, Chen YH. Huang JH, et al. Among authors: chen yh, chen x. J Biol Chem. 2007 Mar 2;282(9):6143-52. doi: 10.1074/jbc.M607701200. Epub 2006 Dec 31. J Biol Chem. 2007. PMID: 17197700 Free article.

4

Surface exposure of the HIV-1 env cytoplasmic tail LLP2 domain during the membrane fusion process: interaction with gp41 fusion core.

Lu L, Zhu Y, Huang J, Chen X, Yang H, Jiang S, Chen YH. Lu L, et al. Among authors: chen yh, chen x. J Biol Chem. 2008 Jun 13;283(24):16723-31. doi: 10.1074/jbc.M801083200. Epub 2008 Apr 11. J Biol Chem. 2008. PMID: 18408000 Free PMC article.

5

Identification of a gp41 core-binding molecule with homologous sequence of human TNNI3K-like protein as a novel human immunodeficiency virus type 1 entry inhibitor.

Zhu Y, Lu L, Xu L, Yang H, Jiang S, Chen YH. Zhu Y, et al. Among authors: chen yh. J Virol. 2010 Sep;84(18):9359-68. doi: 10.1128/JVI.00644-10. Epub 2010 Jun 30. J Virol. 2010. PMID: 20592080 Free PMC article.

6

HIV-1 gp41 core with exposed membrane-proximal external region inducing broad HIV-1 neutralizing antibodies.

Wang J, Tong P, Lu L, Zhou L, Xu L, Jiang S, Chen YH. Wang J, et al. Among authors: chen yh. PLoS One. 2011 Mar 31;6(3):e18233. doi: 10.1371/journal.pone.0018233. PLoS One. 2011. PMID: 21483871 Free PMC article.

7

HIV-1 glycoprotein 41 ectodomain induces activation of the CD74 protein-mediated extracellular signal-regulated kinase/mitogen-activated protein kinase pathway to enhance viral infection.

Zhou C, Lu L, Tan S, Jiang S, Chen YH. Zhou C, et al. Among authors: chen yh. J Biol Chem. 2011 Dec 30;286(52):44869-77. doi: 10.1074/jbc.M111.267393. Epub 2011 Oct 28. J Biol Chem. 2011. PMID: 22039051 Free PMC article.

8

HIV-1 variants with a single-point mutation in the gp41 pocket region exhibiting different susceptibility to HIV fusion inhibitors with pocket- or membrane-binding domain.

Lu L, Tong P, Yu X, Pan C, Zou P, Chen YH, Jiang S. Lu L, et al. Among authors: chen yh. Biochim Biophys Acta. 2012 Dec;1818(12):2950-7. doi: 10.1016/j.bbamem.2012.07.020. Epub 2012 Jul 31. Biochim Biophys Acta. 2012. PMID: 22867851 Free article.

9

Identification of a human protein-derived HIV-1 fusion inhibitor targeting the gp41 fusion core structure.

Chao L, Lu L, Yang H, Zhu Y, Li Y, Wang Q, Yu X, Jiang S, Chen YH. Chao L, et al. Among authors: chen yh. PLoS One. 2013 May 31;8(5):e66156. doi: 10.1371/journal.pone.0066156. Print 2013. PLoS One. 2013. PMID: 23741527 Free PMC article.

10

An engineered HIV-1 gp41 trimeric coiled coil with increased stability and anti-HIV-1 activity: implication for developing anti-HIV microbicides.

Tong P, Lu Z, Chen X, Wang Q, Yu F, Zou P, Yu X, Li Y, Lu L, Chen YH, Jiang S. Tong P, et al. Among authors: chen yh, chen x. J Antimicrob Chemother. 2013 Nov;68(11):2533-44. doi: 10.1093/jac/dkt230. Epub 2013 Jun 21. J Antimicrob Chemother. 2013. PMID: 23794600

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