Roda A - Search Results

1

Dual farnesoid X receptor/TGR5 agonist INT-767 reduces liver injury in the Mdr2-/- (Abcb4-/-) mouse cholangiopathy model by promoting biliary HCO⁻₃ output.

Baghdasaryan A, Claudel T, Gumhold J, Silbert D, Adorini L, Roda A, Vecchiotti S, Gonzalez FJ, Schoonjans K, Strazzabosco M, Fickert P, Trauner M. Baghdasaryan A, et al. Among authors: roda a. Hepatology. 2011 Oct;54(4):1303-12. doi: 10.1002/hep.24537. Hepatology. 2011. PMID: 22006858 Free PMC article.

2

Discovery of 6alpha-ethyl-23(S)-methylcholic acid (S-EMCA, INT-777) as a potent and selective agonist for the TGR5 receptor, a novel target for diabesity.

Pellicciari R, Gioiello A, Macchiarulo A, Thomas C, Rosatelli E, Natalini B, Sardella R, Pruzanski M, Roda A, Pastorini E, Schoonjans K, Auwerx J. Pellicciari R, et al. Among authors: roda a. J Med Chem. 2009 Dec 24;52(24):7958-61. doi: 10.1021/jm901390p. J Med Chem. 2009. PMID: 20014870

3

Semisynthetic bile acid FXR and TGR5 agonists: physicochemical properties, pharmacokinetics, and metabolism in the rat.

Roda A, Pellicciari R, Gioiello A, Neri F, Camborata C, Passeri D, De Franco F, Spinozzi S, Colliva C, Adorini L, Montagnani M, Aldini R. Roda A, et al. J Pharmacol Exp Ther. 2014 Jul;350(1):56-68. doi: 10.1124/jpet.114.214650. Epub 2014 May 1. J Pharmacol Exp Ther. 2014. PMID: 24784847

4

Metabolic Profile of Obeticholic Acid and Endogenous Bile Acids in Rats with Decompensated Liver Cirrhosis.

Roda A, Aldini R, Camborata C, Spinozzi S, Franco P, Cont M, D'Errico A, Vasuri F, Degiovanni A, Maroni L, Adorini L. Roda A, et al. Clin Transl Sci. 2017 Jul;10(4):292-301. doi: 10.1111/cts.12468. Epub 2017 May 23. Clin Transl Sci. 2017. PMID: 28411380 Free PMC article.

5

Avicholic Acid: A Lead Compound from Birds on the Route to Potent TGR5 Modulators.

Pellicciari R, Gioiello A, Sabbatini P, Venturoni F, Nuti R, Colliva C, Rizzo G, Adorini L, Pruzanski M, Roda A, Macchiarulo A. Pellicciari R, et al. Among authors: roda a. ACS Med Chem Lett. 2012 Feb 6;3(4):273-7. doi: 10.1021/ml200256d. eCollection 2012 Apr 12. ACS Med Chem Lett. 2012. PMID: 24900463 Free PMC article.

6

New insights in the physiology and molecular basis of the intestinal bile acid absorption.

Montagnani M, Aldini R, Roda A, Roda E. Montagnani M, et al. Among authors: roda a, roda e. Ital J Gastroenterol Hepatol. 1998 Aug;30(4):435-40. Ital J Gastroenterol Hepatol. 1998. PMID: 9789145 Review.

7

23-Methyl-3 alpha,7 beta-dihydroxy-5 beta-cholan-24-oic acid: dose-response study of biliary secretion in rat.

Roda A, Aldini R, Grigolo B, Simoni P, Roda E, Pellicciari R, Lenzi PL, Natalini B. Roda A, et al. Among authors: roda e. Hepatology. 1988 Nov-Dec;8(6):1571-6. doi: 10.1002/hep.1840080617. Hepatology. 1988. PMID: 3192170

8

Effects of ursodeoxycholic acid on serum liver enzymes and bile acid metabolism in chronic active hepatitis: a dose-response study.

Crosignani A, Battezzati PM, Setchell KD, Camisasca M, Bertolini E, Roda A, Zuin M, Podda M. Crosignani A, et al. Among authors: roda a. Hepatology. 1991 Feb;13(2):339-44. Hepatology. 1991. PMID: 1671665 Clinical Trial.

9

Generation of a novel antibody probe to the apical sodium-dependent bile acid transporter that inhibits ileal bile acid absorption.

Montagnani M, Marangoni A, Roda A, Azzaroli F, Mazzella G, Roda E, Tsivian M, Neri F, Jovani M, Giandinoto M, Caponi A, Aldini R. Montagnani M, et al. Among authors: roda a, roda e. Mol Pharm. 2009 May-Jun;6(3):1012-8. doi: 10.1021/mp800117b. Mol Pharm. 2009. PMID: 19366255

10

Diagnostic effectiveness of serum bile acids in liver diseases as evaluated by multivariate statistical methods.

Festi D, Morselli Labate AM, Roda A, Bazzoli F, Frabboni R, Rucci P, Taroni F, Aldini R, Roda E, Barbara L. Festi D, et al. Among authors: roda a, roda e. Hepatology. 1983 Sep-Oct;3(5):707-13. doi: 10.1002/hep.1840030514. Hepatology. 1983. PMID: 6618438

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