Gonzalez FJ - Search Results

1

Dual farnesoid X receptor/TGR5 agonist INT-767 reduces liver injury in the Mdr2-/- (Abcb4-/-) mouse cholangiopathy model by promoting biliary HCO⁻₃ output.

Baghdasaryan A, Claudel T, Gumhold J, Silbert D, Adorini L, Roda A, Vecchiotti S, Gonzalez FJ, Schoonjans K, Strazzabosco M, Fickert P, Trauner M. Baghdasaryan A, et al. Among authors: gonzalez fj. Hepatology. 2011 Oct;54(4):1303-12. doi: 10.1002/hep.24537. Hepatology. 2011. PMID: 22006858 Free PMC article.

2

Farnesoid X receptor agonists suppress hepatic apolipoprotein CIII expression.

Claudel T, Inoue Y, Barbier O, Duran-Sandoval D, Kosykh V, Fruchart J, Fruchart JC, Gonzalez FJ, Staels B. Claudel T, et al. Among authors: gonzalez fj. Gastroenterology. 2003 Aug;125(2):544-55. doi: 10.1016/s0016-5085(03)00896-5. Gastroenterology. 2003. PMID: 12891557

3

Role of farnesoid X receptor in determining hepatic ABC transporter expression and liver injury in bile duct-ligated mice.

Wagner M, Fickert P, Zollner G, Fuchsbichler A, Silbert D, Tsybrovskyy O, Zatloukal K, Guo GL, Schuetz JD, Gonzalez FJ, Marschall HU, Denk H, Trauner M. Wagner M, et al. Among authors: gonzalez fj. Gastroenterology. 2003 Sep;125(3):825-38. doi: 10.1016/s0016-5085(03)01068-0. Gastroenterology. 2003. PMID: 12949728

4

Role of nuclear bile acid receptor, FXR, in adaptive ABC transporter regulation by cholic and ursodeoxycholic acid in mouse liver, kidney and intestine.

Zollner G, Fickert P, Fuchsbichler A, Silbert D, Wagner M, Arbeiter S, Gonzalez FJ, Marschall HU, Zatloukal K, Denk H, Trauner M. Zollner G, et al. Among authors: gonzalez fj. J Hepatol. 2003 Oct;39(4):480-8. doi: 10.1016/s0168-8278(03)00228-9. J Hepatol. 2003. PMID: 12971955

5

Peroxisome proliferator-activated receptor-beta/delta protects against chemically induced liver toxicity in mice.

Shan W, Nicol CJ, Ito S, Bility MT, Kennett MJ, Ward JM, Gonzalez FJ, Peters JM. Shan W, et al. Among authors: gonzalez fj. Hepatology. 2008 Jan;47(1):225-35. doi: 10.1002/hep.21925. Hepatology. 2008. PMID: 18038451

6

The farnesoid X receptor modulates renal lipid metabolism and diet-induced renal inflammation, fibrosis, and proteinuria.

Wang XX, Jiang T, Shen Y, Adorini L, Pruzanski M, Gonzalez FJ, Scherzer P, Lewis L, Miyazaki-Anzai S, Levi M. Wang XX, et al. Among authors: gonzalez fj. Am J Physiol Renal Physiol. 2009 Dec;297(6):F1587-96. doi: 10.1152/ajprenal.00404.2009. Epub 2009 Sep 23. Am J Physiol Renal Physiol. 2009. PMID: 19776172 Free PMC article.

7

Diabetic nephropathy is accelerated by farnesoid X receptor deficiency and inhibited by farnesoid X receptor activation in a type 1 diabetes model.

Wang XX, Jiang T, Shen Y, Caldas Y, Miyazaki-Anzai S, Santamaria H, Urbanek C, Solis N, Scherzer P, Lewis L, Gonzalez FJ, Adorini L, Pruzanski M, Kopp JB, Verlander JW, Levi M. Wang XX, et al. Among authors: gonzalez fj. Diabetes. 2010 Nov;59(11):2916-27. doi: 10.2337/db10-0019. Epub 2010 Aug 10. Diabetes. 2010. PMID: 20699418 Free PMC article.

8

Farnesoid X receptor represses hepatic human APOA gene expression.

Chennamsetty I, Claudel T, Kostner KM, Baghdasaryan A, Kratky D, Levak-Frank S, Frank S, Gonzalez FJ, Trauner M, Kostner GM. Chennamsetty I, et al. Among authors: gonzalez fj. J Clin Invest. 2011 Sep;121(9):3724-34. doi: 10.1172/JCI45277. Epub 2011 Aug 1. J Clin Invest. 2011. PMID: 21804189 Free PMC article.

9

Inhibition of farnesoid X receptor signaling shows beneficial effects in human obesity.

Gonzalez FJ, Jiang C, Bisson WH, Patterson AD. Gonzalez FJ, et al. J Hepatol. 2015 Jun;62(6):1234-6. doi: 10.1016/j.jhep.2015.02.043. Epub 2015 Mar 5. J Hepatol. 2015. PMID: 25747705 Free PMC article. No abstract available.

10

Farnesoid X receptor activation increases reverse cholesterol transport by modulating bile acid composition and cholesterol absorption in mice.

Xu Y, Li F, Zalzala M, Xu J, Gonzalez FJ, Adorini L, Lee YK, Yin L, Zhang Y. Xu Y, et al. Among authors: gonzalez fj. Hepatology. 2016 Oct;64(4):1072-85. doi: 10.1002/hep.28712. Epub 2016 Jul 30. Hepatology. 2016. PMID: 27359351 Free PMC article.

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