Netto CD - Search Results

1

Pterocarpanquinones, aza-pterocarpanquinone and derivatives: synthesis, antineoplasic activity on human malignant cell lines and antileishmanial activity on Leishmania amazonensis.

Buarque CD, Militão GC, Lima DJ, Costa-Lotufo LV, Pessoa C, de Moraes MO, Cunha-Junior EF, Torres-Santos EC, Netto CD, Costa PR. Buarque CD, et al. Among authors: netto cd. Bioorg Med Chem. 2011 Nov 15;19(22):6885-91. doi: 10.1016/j.bmc.2011.09.025. Epub 2011 Sep 21. Bioorg Med Chem. 2011. PMID: 22000949 Free article.

2

Structure-activity relationship of wedelolactone analogues: structural requirements for inhibition of Na+, K+ -ATPase and binding to the central benzodiazepine receptor.

Pôças ES, Lopes DV, da Silva AJ, Pimenta PH, Leitão FB, Netto CD, Buarque CD, Brito FV, Costa PR, Noël F. Pôças ES, et al. Among authors: netto cd. Bioorg Med Chem. 2006 Dec 1;14(23):7962-6. doi: 10.1016/j.bmc.2006.07.053. Epub 2006 Aug 30. Bioorg Med Chem. 2006. PMID: 16945543

3

(+/-)-3,4-Dihydroxy-8,9-methylenedioxypterocarpan and derivatives: cytotoxic effect on human leukemia cell lines.

Netto CD, Santos ES, Castro CP, da Silva AJ, Rumjanek VM, Costa PR. Netto CD, et al. Eur J Med Chem. 2009 Feb;44(2):920-5. doi: 10.1016/j.ejmech.2008.01.027. Epub 2008 Feb 2. Eur J Med Chem. 2009. PMID: 18468732

4

Comparison of the cytotoxic effect of lapachol, alpha-lapachone and pentacyclic 1,4-naphthoquinones on human leukemic cells.

Salustiano EJ, Netto CD, Fernandes RF, da Silva AJ, Bacelar TS, Castro CP, Buarque CD, Maia RC, Rumjanek VM, Costa PR. Salustiano EJ, et al. Among authors: netto cd. Invest New Drugs. 2010 Apr;28(2):139-44. doi: 10.1007/s10637-009-9231-y. Epub 2009 Mar 4. Invest New Drugs. 2010. PMID: 19255723

5

New pterocarpanquinones: synthesis, antineoplasic activity on cultured human malignant cell lines and TNF-alpha modulation in human PBMC cells.

Netto CD, da Silva AJ, Salustiano EJ, Bacelar TS, Riça IG, Cavalcante MC, Rumjanek VM, Costa PR. Netto CD, et al. Bioorg Med Chem. 2010 Feb 15;18(4):1610-6. doi: 10.1016/j.bmc.2009.12.073. Epub 2010 Jan 6. Bioorg Med Chem. 2010. PMID: 20117936 Free article.

6

LQB-118, a pterocarpanquinone structurally related to lapachol [2-hydroxy-3-(3-methyl-2-butenyl)-1,4-naphthoquinone]: a novel class of agent with high apoptotic effect in chronic myeloid leukemia cells.

Maia RC, Vasconcelos FC, de Sá Bacelar T, Salustiano EJ, da Silva LF, Pereira DL, Moellman-Coelho A, Netto CD, da Silva AJ, Rumjanek VM, Costa PR. Maia RC, et al. Among authors: netto cd. Invest New Drugs. 2011 Dec;29(6):1143-55. doi: 10.1007/s10637-010-9453-z. Epub 2010 May 25. Invest New Drugs. 2011. PMID: 20499132

7

Effectiveness of the local or oral delivery of the novel naphthopterocarpanquinone LQB-118 against cutaneous leishmaniasis.

da Cunha-Júnior EF, Pacienza-Lima W, Ribeiro GA, Netto CD, do Canto-Cavalheiro MM, da Silva AJ, Costa PR, Rossi-Bergmann B, Torres-Santos EC. da Cunha-Júnior EF, et al. Among authors: netto cd. J Antimicrob Chemother. 2011 Jul;66(7):1555-9. doi: 10.1093/jac/dkr158. Epub 2011 Apr 29. J Antimicrob Chemother. 2011. PMID: 21531758

8

A new type of pterocarpanquinone that affects Toxoplasma gondii tachyzoites in vitro.

Portes Jde A, Netto CD, da Silva AJ, Costa PR, DaMatta RA, dos Santos TA, De Souza W, Seabra SH. Portes Jde A, et al. Among authors: netto cd. Vet Parasitol. 2012 May 25;186(3-4):261-9. doi: 10.1016/j.vetpar.2011.11.008. Epub 2011 Nov 7. Vet Parasitol. 2012. PMID: 22177332

9

LQB-118, an orally active pterocarpanquinone, induces selective oxidative stress and apoptosis in Leishmania amazonensis.

Ribeiro GA, Cunha-Júnior EF, Pinheiro RO, da-Silva SA, Canto-Cavalheiro MM, da Silva AJ, Costa PR, Netto CD, Melo RC, Almeida-Amaral EE, Torres-Santos EC. Ribeiro GA, et al. Among authors: netto cd. J Antimicrob Chemother. 2013 Apr;68(4):789-99. doi: 10.1093/jac/dks498. Epub 2013 Jan 3. J Antimicrob Chemother. 2013. PMID: 23288404

10

The pterocarpanquinone LQB-118 inhibits tumor cell proliferation by downregulation of c-Myc and cyclins D1 and B1 mRNA and upregulation of p21 cell cycle inhibitor expression.

Martino T, Magalhães FC, Justo GA, Coelho MG, Netto CD, Costa PR, Sabino KC. Martino T, et al. Among authors: netto cd. Bioorg Med Chem. 2014 Jun 15;22(12):3115-22. doi: 10.1016/j.bmc.2014.04.025. Epub 2014 Apr 20. Bioorg Med Chem. 2014. PMID: 24794748

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