Zhou Y - Search Results

1

Identification of inhibitors against p90 ribosomal S6 kinase 2 (RSK2) through structure-based virtual screening with the inhibitor-constrained refined homology model.

Li S, Zhou Y, Lu W, Zhong Y, Song W, Liu K, Huang J, Zhao Z, Xu Y, Liu X, Li H. Li S, et al. Among authors: zhou y. J Chem Inf Model. 2011 Nov 28;51(11):2939-47. doi: 10.1021/ci2002445. Epub 2011 Oct 21. J Chem Inf Model. 2011. PMID: 21995341

2

Enhancing the Sensitivity of Pharmacophore-Based Virtual Screening by Incorporating Customized ZBG Features: A Case Study Using Histone Deacetylase 8.

Hou X, Du J, Liu R, Zhou Y, Li M, Xu W, Fang H. Hou X, et al. Among authors: zhou y. J Chem Inf Model. 2015 Apr 27;55(4):861-71. doi: 10.1021/ci500762z. Epub 2015 Mar 16. J Chem Inf Model. 2015. PMID: 25757142

3

Design, synthesis, and preliminary bioactivity evaluation of N-benzylpyrimidin-2-amine derivatives as novel histone deacetylase inhibitor.

Zhou Y, Dun Y, Fu H, Wang L, Pan X, Yang X, Fang H. Zhou Y, et al. Chem Biol Drug Des. 2017 Nov;90(5):936-942. doi: 10.1111/cbdd.13019. Epub 2017 Jun 12. Chem Biol Drug Des. 2017. PMID: 28489276

4

1-Phenyl-1H-indole derivatives as a new class of Bcl-2/Mcl-1 dual inhibitors: Design, synthesis, and preliminary biological evaluation.

Xu G, Liu T, Zhou Y, Yang X, Fang H. Xu G, et al. Among authors: zhou y. Bioorg Med Chem. 2017 Oct 15;25(20):5548-5556. doi: 10.1016/j.bmc.2017.08.024. Epub 2017 Aug 15. Bioorg Med Chem. 2017. PMID: 28866374

5

Development of naringenin-O-alkylamine derivatives as multifunctional agents for the treatment of Alzheimer's disease.

Yang J, Zhou Y, Ban Y, Mi J, He Y, Li X, Liu Z, Wang K, Zhu G, Liu W, Tan Z, Sang Z. Yang J, et al. Among authors: zhou y. J Enzyme Inhib Med Chem. 2022 Dec;37(1):792-816. doi: 10.1080/14756366.2022.2041627. J Enzyme Inhib Med Chem. 2022. PMID: 35193434 Free PMC article.

6

HDAC-Bax Multiple Ligands Enhance Bax-Dependent Apoptosis in HeLa Cells.

Liang T, Zhou Y, Elhassan RM, Hou X, Yang X, Fang H. Liang T, et al. Among authors: zhou y. J Med Chem. 2020 Oct 22;63(20):12083-12099. doi: 10.1021/acs.jmedchem.0c01454. Epub 2020 Oct 6. J Med Chem. 2020. PMID: 33021789

7

Development of naringenin-O-carbamate derivatives as multi-target-directed liagnds for the treatment of Alzheimer's disease.

Mi J, He Y, Yang J, Zhou Y, Zhu G, Wu A, Liu W, Sang Z. Mi J, et al. Among authors: zhou y. Bioorg Med Chem Lett. 2022 Mar 15;60:128574. doi: 10.1016/j.bmcl.2022.128574. Epub 2022 Jan 19. Bioorg Med Chem Lett. 2022. PMID: 35065231

8

One-pot two-strain system based on glucaric acid biosensor for rapid screening of myo-inositol oxygenase mutations and glucaric acid production in recombinant cells.

Zheng S, Hou J, Zhou Y, Fang H, Wang TT, Liu F, Wang FS, Sheng JZ. Zheng S, et al. Among authors: zhou y. Metab Eng. 2018 Sep;49:212-219. doi: 10.1016/j.ymben.2018.08.005. Epub 2018 Aug 18. Metab Eng. 2018. PMID: 30125674

9

Design, Synthesis, and Biological Evaluation of 2,4-Imidazolinedione Derivatives as HDAC6 Isoform-Selective Inhibitors.

Liang T, Hou X, Zhou Y, Yang X, Fang H. Liang T, et al. Among authors: zhou y. ACS Med Chem Lett. 2019 Jul 5;10(8):1122-1127. doi: 10.1021/acsmedchemlett.9b00084. eCollection 2019 Aug 8. ACS Med Chem Lett. 2019. PMID: 31413795 Free PMC article.

10

Discovery of Peptide Boronate Derivatives as Histone Deacetylase and Proteasome Dual Inhibitors for Overcoming Bortezomib Resistance of Multiple Myeloma.

Zhou Y, Liu X, Xue J, Liu L, Liang T, Li W, Yang X, Hou X, Fang H. Zhou Y, et al. J Med Chem. 2020 May 14;63(9):4701-4715. doi: 10.1021/acs.jmedchem.9b02161. Epub 2020 Apr 23. J Med Chem. 2020. PMID: 32267687

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