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154 results

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Page 1
MYT1L is a candidate gene for intellectual disability in patients with 2p25.3 (2pter) deletions.
Stevens SJ, van Ravenswaaij-Arts CM, Janssen JW, Klein Wassink-Ruiter JS, van Essen AJ, Dijkhuizen T, van Rheenen J, Heuts-Vijgen R, Stegmann AP, Smeets EE, Engelen JJ. Stevens SJ, et al. Among authors: van essen aj, van ravenswaaij arts cm, van rheenen j. Am J Med Genet A. 2011 Nov;155A(11):2739-45. doi: 10.1002/ajmg.a.34274. Epub 2011 Oct 11. Am J Med Genet A. 2011. PMID: 21990140
A guideline for the clinical management of basal cell naevus syndrome (Gorlin-Goltz syndrome).
Verkouteren BJA, Cosgun B, Reinders MGHC, Kessler PAWK, Vermeulen RJ, Klaassens M, Lambrechts S, van Rheenen JR, van Geel M, Vreeburg M, Mosterd K. Verkouteren BJA, et al. Among authors: van rheenen jr, van geel m. Br J Dermatol. 2022 Feb;186(2):215-226. doi: 10.1111/bjd.20700. Epub 2021 Nov 8. Br J Dermatol. 2022. PMID: 34375441 Free PMC article.
Heterogeneity-driven phenotypic plasticity and treatment response in branched-organoid models of pancreatic ductal adenocarcinoma.
Papargyriou A, Najajreh M, Cook DP, Maurer CH, Bärthel S, Messal HA, Ravichandran SK, Richter T, Knolle M, Metzler T, Shastri AR, Öllinger R, Jasper J, Schmidleitner L, Wang S, Schneeweis C, Ishikawa-Ankerhold H, Engleitner T, Mataite L, Semina M, Trabulssi H, Lange S, Ravichandra A, Schuster M, Mueller S, Peschke K, Schäfer A, Dobiasch S, Combs SE, Schmid RM, Bausch AR, Braren R, Heid I, Scheel CH, Schneider G, Zeigerer A, Luecken MD, Steiger K, Kaissis G, van Rheenen J, Theis FJ, Saur D, Rad R, Reichert M. Papargyriou A, et al. Among authors: van rheenen j. Nat Biomed Eng. 2024 Dec 10. doi: 10.1038/s41551-024-01273-9. Online ahead of print. Nat Biomed Eng. 2024. PMID: 39658630
The oestrous cycle stage affects mammary tumour sensitivity to chemotherapy.
Bornes L, van Winden LJ, Geurts VCM, de Bruijn B, Azarang L, Lanfermeijer M, Caruso M, Proost N, Boeije M, Lohuis JO, Belthier G, Noguera Delgado E, de Gruil N, Kroep JR, van de Ven M, Menezes R, Wesseling J, Kok M, Linn S, Broeks A, van Rossum HH, Scheele CLGJ, van Rheenen J. Bornes L, et al. Among authors: van rheenen j. Nature. 2025 Jan;637(8044):195-204. doi: 10.1038/s41586-024-08276-1. Epub 2024 Dec 4. Nature. 2025. PMID: 39633046 Free PMC article.
A novel lineage-tracing tool reveals that hypoxic tumor cells drive tumor relapse after radiotherapy.
Menegakis A, Vennin C, Ient J, Groot AJ, Krenning L, Klompmaker R, Friskes A, Ilic M, Yaromina A, Harkes R, van den Broek B, Jakob Sonke J, De Jong M, Piepers J, van Rheenen J, Vooijs MA, Medema RH. Menegakis A, et al. Among authors: van rheenen j. Radiother Oncol. 2025 Jan;202:110592. doi: 10.1016/j.radonc.2024.110592. Epub 2024 Oct 18. Radiother Oncol. 2025. PMID: 39427933 Free article.
Mechanisms that clear mutations drive field cancerization in mammary tissue.
Ciwinska M, Messal HA, Hristova HR, Lutz C, Bornes L, Chalkiadakis T, Harkes R, Langedijk NSM, Hutten SJ, Menezes RX, Jonkers J, Prekovic S; Grand Challenge PRECISION consortium; Simons BD, Scheele CLGJ, van Rheenen J. Ciwinska M, et al. Among authors: van rheenen j. Nature. 2024 Sep;633(8028):198-206. doi: 10.1038/s41586-024-07882-3. Epub 2024 Sep 4. Nature. 2024. PMID: 39232148 Free PMC article.
Predictive gene expression profile for adjuvant taxane benefit in breast cancer in the MATADOR trial.
Opdam M, van Rossum AGJ, Hoogstraat M, Bounova G, Horlings HM, van Werkhoven E, Mandjes IAM, van Leeuwen-Stok AE, Canisius S, van Tinteren H, Imholz ALT, Portielje JEA, Bos MEMM, Bakker S, Wesseling J, Kester L, van Rheenen J, Rutgers EJ, de Menezes RX, Wessels LFA, Kok M, Oosterkamp HM, Linn SC; MATADOR trialists’ group for the Dutch Breast Cancer Research Group (BOOG). Opdam M, et al. Among authors: van rheenen j. iScience. 2024 Jun 29;27(8):110425. doi: 10.1016/j.isci.2024.110425. eCollection 2024 Aug 16. iScience. 2024. PMID: 39206149 Free PMC article.
DCIS knowledge of women choosing between active surveillance and surgery for low-risk DCIS.
Engelhardt EG, Schmitz RSJM, Gerritsma MA, Sondermeijer CMT, Verschuur E, Houtzager JHE, Griffioen R, Bijker N, Mann RM, Retèl V, van Duijnhoven FH, Wesseling J, Bleiker EMA; Grand Challenge PRECISION Consortium. Engelhardt EG, et al. Breast. 2024 Oct;77:103764. doi: 10.1016/j.breast.2024.103764. Epub 2024 Jul 2. Breast. 2024. PMID: 38970983 Free PMC article.
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