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A mitochondria-targeted inhibitor of cytochrome c peroxidase mitigates radiation-induced death.
Atkinson J, Kapralov AA, Yanamala N, Tyurina YY, Amoscato AA, Pearce L, Peterson J, Huang Z, Jiang J, Samhan-Arias AK, Maeda A, Feng W, Wasserloos K, Belikova NA, Tyurin VA, Wang H, Fletcher J, Wang Y, Vlasova II, Klein-Seetharaman J, Stoyanovsky DA, Bayîr H, Pitt BR, Epperly MW, Greenberger JS, Kagan VE. Atkinson J, et al. Nat Commun. 2011 Oct 11;2:497. doi: 10.1038/ncomms1499. Nat Commun. 2011. PMID: 21988913 Free PMC article.
Topography of tyrosine residues and their involvement in peroxidation of polyunsaturated cardiolipin in cytochrome c/cardiolipin peroxidase complexes.
Kapralov AA, Yanamala N, Tyurina YY, Castro L, Samhan-Arias A, Vladimirov YA, Maeda A, Weitz AA, Peterson J, Mylnikov D, Demicheli V, Tortora V, Klein-Seetharaman J, Radi R, Kagan VE. Kapralov AA, et al. Biochim Biophys Acta. 2011 Sep;1808(9):2147-55. doi: 10.1016/j.bbamem.2011.04.009. Epub 2011 Apr 29. Biochim Biophys Acta. 2011. PMID: 21550335 Free PMC article.
Mitochondrial targeting of electron scavenging antioxidants: Regulation of selective oxidation vs random chain reactions.
Kagan VE, Wipf P, Stoyanovsky D, Greenberger JS, Borisenko G, Belikova NA, Yanamala N, Samhan Arias AK, Tungekar MA, Jiang J, Tyurina YY, Ji J, Klein-Seetharaman J, Pitt BR, Shvedova AA, Bayir H. Kagan VE, et al. Adv Drug Deliv Rev. 2009 Nov 30;61(14):1375-85. doi: 10.1016/j.addr.2009.06.008. Epub 2009 Aug 27. Adv Drug Deliv Rev. 2009. PMID: 19716396 Free PMC article. Review.
Oxidized phospholipids as biomarkers of tissue and cell damage with a focus on cardiolipin.
Samhan-Arias AK, Ji J, Demidova OM, Sparvero LJ, Feng W, Tyurin V, Tyurina YY, Epperly MW, Shvedova AA, Greenberger JS, Bayır H, Kagan VE, Amoscato AA. Samhan-Arias AK, et al. Biochim Biophys Acta. 2012 Oct;1818(10):2413-23. doi: 10.1016/j.bbamem.2012.03.014. Epub 2012 Mar 23. Biochim Biophys Acta. 2012. PMID: 22464971 Free PMC article.
Structural characterization of cardiolipin-driven activation of cytochrome c into a peroxidase and membrane perturbation.
Mohammadyani D, Yanamala N, Samhan-Arias AK, Kapralov AA, Stepanov G, Nuar N, Planas-Iglesias J, Sanghera N, Kagan VE, Klein-Seetharaman J. Mohammadyani D, et al. Biochim Biophys Acta Biomembr. 2018 May;1860(5):1057-1068. doi: 10.1016/j.bbamem.2018.01.009. Epub 2018 Jan 6. Biochim Biophys Acta Biomembr. 2018. PMID: 29317202 Free article.
40 results