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Page 1
Novel Inverse Binding Mode of Indirubin Derivatives Yields Improved Selectivity for DYRK Kinases.
Myrianthopoulos V, Kritsanida M, Gaboriaud-Kolar N, Magiatis P, Ferandin Y, Durieu E, Lozach O, Cappel D, Soundararajan M, Filippakopoulos P, Sherman W, Knapp S, Meijer L, Mikros E, Skaltsounis AL. Myrianthopoulos V, et al. Among authors: skaltsounis al. ACS Med Chem Lett. 2013 Jan 10;4(1):22-26. doi: 10.1021/ml300207a. Epub 2012 Nov 1. ACS Med Chem Lett. 2013. PMID: 23336033 Free PMC article.
Glycogen phosphorylase inhibitors: a patent review (2008 - 2012).
Gaboriaud-Kolar N, Skaltsounis AL. Gaboriaud-Kolar N, et al. Among authors: skaltsounis al. Expert Opin Ther Pat. 2013 Aug;23(8):1017-32. doi: 10.1517/13543776.2013.794790. Epub 2013 Apr 30. Expert Opin Ther Pat. 2013. PMID: 23627914 Review.
An inhibitor-driven study for enhancing the selectivity of indirubin derivatives towards leishmanial Glycogen Synthase Kinase-3 over leishmanial cdc2-related protein kinase 3.
Efstathiou A, Gaboriaud-Kolar N, Smirlis D, Myrianthopoulos V, Vougogiannopoulou K, Alexandratos A, Kritsanida M, Mikros E, Soteriadou K, Skaltsounis AL. Efstathiou A, et al. Among authors: skaltsounis al. Parasit Vectors. 2014 May 20;7:234. doi: 10.1186/1756-3305-7-234. Parasit Vectors. 2014. PMID: 24886176 Free PMC article.
A colorful history: the evolution of indigoids.
Gaboriaud-Kolar N, Nam S, Skaltsounis AL. Gaboriaud-Kolar N, et al. Among authors: skaltsounis al. Prog Chem Org Nat Prod. 2014;99:69-145. doi: 10.1007/978-3-319-04900-7_2. Prog Chem Org Nat Prod. 2014. PMID: 25296438 Review. No abstract available.
Indirubin derivatives: a patent review (2010 - present).
Gaboriaud-Kolar N, Vougogiannopoulou K, Skaltsounis AL. Gaboriaud-Kolar N, et al. Among authors: skaltsounis al. Expert Opin Ther Pat. 2015 May;25(5):583-93. doi: 10.1517/13543776.2015.1019865. Expert Opin Ther Pat. 2015. PMID: 25887337 Review.
From Drug Screening to Target Deconvolution: a Target-Based Drug Discovery Pipeline Using Leishmania Casein Kinase 1 Isoform 2 To Identify Compounds with Antileishmanial Activity.
Durieu E, Prina E, Leclercq O, Oumata N, Gaboriaud-Kolar N, Vougogiannopoulou K, Aulner N, Defontaine A, No JH, Ruchaud S, Skaltsounis AL, Galons H, Späth GF, Meijer L, Rachidi N. Durieu E, et al. Among authors: skaltsounis al. Antimicrob Agents Chemother. 2016 Apr 22;60(5):2822-33. doi: 10.1128/AAC.00021-16. Print 2016 May. Antimicrob Agents Chemother. 2016. PMID: 26902771 Free PMC article.
Discovery and Optimization of a Selective Ligand for the Switch/Sucrose Nonfermenting-Related Bromodomains of Polybromo Protein-1 by the Use of Virtual Screening and Hydration Analysis.
Myrianthopoulos V, Gaboriaud-Kolar N, Tallant C, Hall ML, Grigoriou S, Brownlee PM, Fedorov O, Rogers C, Heidenreich D, Wanior M, Drosos N, Mexia N, Savitsky P, Bagratuni T, Kastritis E, Terpos E, Filippakopoulos P, Müller S, Skaltsounis AL, Downs JA, Knapp S, Mikros E. Myrianthopoulos V, et al. Among authors: skaltsounis al. J Med Chem. 2016 Oct 13;59(19):8787-8803. doi: 10.1021/acs.jmedchem.6b00355. Epub 2016 Sep 27. J Med Chem. 2016. PMID: 27617704 Free PMC article.
276 results