Ojida A - Search Results

1

Discovery of orteronel (TAK-700), a naphthylmethylimidazole derivative, as a highly selective 17,20-lyase inhibitor with potential utility in the treatment of prostate cancer.

Kaku T, Hitaka T, Ojida A, Matsunaga N, Adachi M, Tanaka T, Hara T, Yamaoka M, Kusaka M, Okuda T, Asahi S, Furuya S, Tasaka A. Kaku T, et al. Among authors: ojida a. Bioorg Med Chem. 2011 Nov 1;19(21):6383-99. doi: 10.1016/j.bmc.2011.08.066. Epub 2011 Sep 1. Bioorg Med Chem. 2011. PMID: 21978946

2

Fluorescence-Based Detection of Fatty Acid β-Oxidation in Cells and Tissues Using Quinone Methide-Releasing Probes.

Uchinomiya S, Nagaura T, Weber M, Matsuo Y, Zenmyo N, Yoshida Y, Tsuruta A, Koyanagi S, Ohdo S, Matsunaga N, Ojida A. Uchinomiya S, et al. Among authors: ojida a. J Am Chem Soc. 2023 Apr 12;145(14):8248-8260. doi: 10.1021/jacs.3c02043. Epub 2023 Apr 3. J Am Chem Soc. 2023. PMID: 37011039

3

Improved polarized light microscopic detection of gouty crystals via dissolution with formalin and ethylenediamine tetraacetic acid.

Hemstapat R, Duangiad P, Tangketsarawan B, Phuagpan T, Chienwiwattanawong S, Tangsrianugul N, Ojida A, Wongkongkatep J. Hemstapat R, et al. Among authors: ojida a. Sci Rep. 2023 May 9;13(1):7505. doi: 10.1038/s41598-023-34570-5. Sci Rep. 2023. PMID: 37160946 Free PMC article.

4

Highly enantioselective reformatsky reaction of ketones: chelation-assisted enantioface discrimination.

Ojida A, Yamano T, Taya N, Tasaka A. Ojida A, et al. Org Lett. 2002 Sep 5;4(18):3051-4. doi: 10.1021/ol0263189. Org Lett. 2002. PMID: 12201714

5

C(17,20)-lyase inhibitors. Part 2: design, synthesis and structure-activity relationships of (2-naphthylmethyl)-1H-imidazoles as novel C(17,20)-lyase inhibitors.

Matsunaga N, Kaku T, Ojida A, Tanaka T, Hara T, Yamaoka M, Kusaka M, Tasaka A. Matsunaga N, et al. Among authors: ojida a. Bioorg Med Chem. 2004 Aug 15;12(16):4313-36. doi: 10.1016/j.bmc.2004.06.016. Bioorg Med Chem. 2004. PMID: 15265485

6

17,20-lyase inhibitors. Part 4: design, synthesis and structure-activity relationships of naphthylmethylimidazole derivatives as novel 17,20-lyase inhibitors.

Kaku T, Matsunaga N, Ojida A, Tanaka T, Hara T, Yamaoka M, Kusaka M, Tasaka A. Kaku T, et al. Among authors: ojida a. Bioorg Med Chem. 2011 Mar 1;19(5):1751-70. doi: 10.1016/j.bmc.2011.01.017. Epub 2011 Jan 15. Bioorg Med Chem. 2011. PMID: 21316976

7

Design of a binuclear Ni(II)-iminodiacetic acid (IDA) complex for selective recognition and covalent labeling of His-tag fused proteins.

Takahira I, Fuchida H, Tabata S, Shindo N, Uchinomiya S, Hamachi I, Ojida A. Takahira I, et al. Among authors: ojida a. Bioorg Med Chem Lett. 2014 Jul 1;24(13):2855-8. doi: 10.1016/j.bmcl.2014.04.096. Epub 2014 May 4. Bioorg Med Chem Lett. 2014. PMID: 24835629

8

Recent progress in covalent warheads for in vivo targeting of endogenous proteins.

Shindo N, Ojida A. Shindo N, et al. Among authors: ojida a. Bioorg Med Chem. 2021 Oct 1;47:116386. doi: 10.1016/j.bmc.2021.116386. Epub 2021 Aug 27. Bioorg Med Chem. 2021. PMID: 34509863 Review.

9

Identification of a new class of low molecular weight antagonists against the chemokine receptor CXCR4 having the dipicolylamine-zinc(II) complex structure.

Tamamura H, Ojida A, Ogawa T, Tsutsumi H, Masuno H, Nakashima H, Yamamoto N, Hamachi I, Fujii N. Tamamura H, et al. Among authors: ojida a. J Med Chem. 2006 Jun 1;49(11):3412-5. doi: 10.1021/jm060025u. J Med Chem. 2006. PMID: 16722661

10

Discovery of highly reactive peptide tag by ELISA-type screening for specific cysteine conjugation.

Kurashige N, Fuchida H, Tabata S, Uchinomiya S, Ojida A. Kurashige N, et al. Among authors: ojida a. Bioorg Med Chem Lett. 2017 Aug 1;27(15):3486-3489. doi: 10.1016/j.bmcl.2017.05.069. Epub 2017 May 24. Bioorg Med Chem Lett. 2017. PMID: 28576616

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