Solinas G - Search Results

1

Saturated fatty acids induce c-Src clustering within membrane subdomains, leading to JNK activation.

Holzer RG, Park EJ, Li N, Tran H, Chen M, Choi C, Solinas G, Karin M. Holzer RG, et al. Among authors: solinas g. Cell. 2011 Sep 30;147(1):173-84. doi: 10.1016/j.cell.2011.08.034. Cell. 2011. PMID: 21962514 Free PMC article.

2

Saturated fatty acids inhibit induction of insulin gene transcription by JNK-mediated phosphorylation of insulin-receptor substrates.

Solinas G, Naugler W, Galimi F, Lee MS, Karin M. Solinas G, et al. Proc Natl Acad Sci U S A. 2006 Oct 31;103(44):16454-9. doi: 10.1073/pnas.0607626103. Epub 2006 Oct 18. Proc Natl Acad Sci U S A. 2006. PMID: 17050683 Free PMC article.

3

The E3 ubiquitin ligase itch couples JNK activation to TNFalpha-induced cell death by inducing c-FLIP(L) turnover.

Chang L, Kamata H, Solinas G, Luo JL, Maeda S, Venuprasad K, Liu YC, Karin M. Chang L, et al. Among authors: solinas g. Cell. 2006 Feb 10;124(3):601-13. doi: 10.1016/j.cell.2006.01.021. Cell. 2006. PMID: 16469705 Free article.

4

JNK1 in hematopoietically derived cells contributes to diet-induced inflammation and insulin resistance without affecting obesity.

Solinas G, Vilcu C, Neels JG, Bandyopadhyay GK, Luo JL, Naugler W, Grivennikov S, Wynshaw-Boris A, Scadeng M, Olefsky JM, Karin M. Solinas G, et al. Cell Metab. 2007 Nov;6(5):386-97. doi: 10.1016/j.cmet.2007.09.011. Cell Metab. 2007. PMID: 17983584 Free article.

5

Identification of a new JNK inhibitor targeting the JNK-JIP interaction site.

Stebbins JL, De SK, Machleidt T, Becattini B, Vazquez J, Kuntzen C, Chen LH, Cellitti JF, Riel-Mehan M, Emdadi A, Solinas G, Karin M, Pellecchia M. Stebbins JL, et al. Among authors: solinas g. Proc Natl Acad Sci U S A. 2008 Oct 28;105(43):16809-13. doi: 10.1073/pnas.0805677105. Epub 2008 Oct 15. Proc Natl Acad Sci U S A. 2008. PMID: 18922779 Free PMC article.

6

JNK1 and IKKbeta: molecular links between obesity and metabolic dysfunction.

Solinas G, Karin M. Solinas G, et al. FASEB J. 2010 Aug;24(8):2596-611. doi: 10.1096/fj.09-151340. Epub 2010 Apr 6. FASEB J. 2010. PMID: 20371626 Review.

7

Functional in vivo interactions between JNK1 and JNK2 isoforms in obesity and insulin resistance.

Tuncman G, Hirosumi J, Solinas G, Chang L, Karin M, Hotamisligil GS. Tuncman G, et al. Among authors: solinas g. Proc Natl Acad Sci U S A. 2006 Jul 11;103(28):10741-6. doi: 10.1073/pnas.0603509103. Epub 2006 Jul 3. Proc Natl Acad Sci U S A. 2006. PMID: 16818881 Free PMC article.

8

JNK at the crossroad of obesity, insulin resistance, and cell stress response.

Solinas G, Becattini B. Solinas G, et al. Mol Metab. 2016 Dec 8;6(2):174-184. doi: 10.1016/j.molmet.2016.12.001. eCollection 2017 Feb. Mol Metab. 2016. PMID: 28180059 Free PMC article. Review.

9

Insulin-Driven PI3K-AKT Signaling in the Hepatocyte Is Mediated by Redundant PI3Kα and PI3Kβ Activities and Is Promoted by RAS.

Molinaro A, Becattini B, Mazzoli A, Bleve A, Radici L, Maxvall I, Sopasakis VR, Molinaro A, Bäckhed F, Solinas G. Molinaro A, et al. Among authors: solinas g. Cell Metab. 2019 Jun 4;29(6):1400-1409.e5. doi: 10.1016/j.cmet.2019.03.010. Epub 2019 Apr 11. Cell Metab. 2019. PMID: 30982732 Free article.

10

Role of JNK activation in pancreatic beta-cell death by streptozotocin.

Cheon H, Cho JM, Kim S, Baek SH, Lee MK, Kim KW, Yu SW, Solinas G, Kim SS, Lee MS. Cheon H, et al. Among authors: solinas g. Mol Cell Endocrinol. 2010 Jun 10;321(2):131-7. doi: 10.1016/j.mce.2010.02.016. Epub 2010 Feb 20. Mol Cell Endocrinol. 2010. PMID: 20176078

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