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The clinical impact and molecular biology of del(17p) in multiple myeloma treated with conventional or thalidomide-based therapy.
Boyd KD, Ross FM, Tapper WJ, Chiecchio L, Dagrada G, Konn ZJ, Gonzalez D, Walker BA, Hockley SL, Wardell CP, Gregory WM, Child JA, Jackson GH, Davies FE, Morgan GJ; NCRI Haematology Oncology Studies Group. Boyd KD, et al. Among authors: dagrada g. Genes Chromosomes Cancer. 2011 Oct;50(10):765-74. doi: 10.1002/gcc.20899. Genes Chromosomes Cancer. 2011. PMID: 21961181 Clinical Trial.
Gene mapping and expression analysis of 16q loss of heterozygosity identifies WWOX and CYLD as being important in determining clinical outcome in multiple myeloma.
Jenner MW, Leone PE, Walker BA, Ross FM, Johnson DC, Gonzalez D, Chiecchio L, Dachs Cabanas E, Dagrada GP, Nightingale M, Protheroe RK, Stockley D, Else M, Dickens NJ, Cross NC, Davies FE, Morgan GJ. Jenner MW, et al. Blood. 2007 Nov 1;110(9):3291-300. doi: 10.1182/blood-2007-02-075069. Epub 2007 Jul 3. Blood. 2007. PMID: 17609426 Free article.
Deletions of CDKN2C in multiple myeloma: biological and clinical implications.
Leone PE, Walker BA, Jenner MW, Chiecchio L, Dagrada G, Protheroe RK, Johnson DC, Dickens NJ, Brito JL, Else M, Gonzalez D, Ross FM, Chen-Kiang S, Davies FE, Morgan GJ. Leone PE, et al. Among authors: dagrada g. Clin Cancer Res. 2008 Oct 1;14(19):6033-41. doi: 10.1158/1078-0432.CCR-08-0347. Clin Cancer Res. 2008. PMID: 18829482 Free PMC article.
Frequent upregulation of MYC in plasma cell leukemia.
Chiecchio L, Dagrada GP, White HE, Towsend MR, Protheroe RK, Cheung KL, Stockley DM, Orchard KH, Cross NC, Harrison CJ, Ross FM; UK Myeloma Forum. Chiecchio L, et al. Genes Chromosomes Cancer. 2009 Jul;48(7):624-36. doi: 10.1002/gcc.20670. Genes Chromosomes Cancer. 2009. PMID: 19396865
The t(14;20) is a poor prognostic factor in myeloma but is associated with long-term stable disease in monoclonal gammopathies of undetermined significance.
Ross FM, Chiecchio L, Dagrada G, Protheroe RK, Stockley DM, Harrison CJ, Cross NC, Szubert AJ, Drayson MT, Morgan GJ; UK Myeloma Forum. Ross FM, et al. Among authors: dagrada g. Haematologica. 2010 Jul;95(7):1221-5. doi: 10.3324/haematol.2009.016329. Epub 2010 Apr 21. Haematologica. 2010. PMID: 20410185 Free PMC article.
76 results