Liu D - Search Results

1

Computational screening for active compounds targeting protein sequences: methodology and experimental validation.

Wang F, Liu D, Wang H, Luo C, Zheng M, Liu H, Zhu W, Luo X, Zhang J, Jiang H. Wang F, et al. Among authors: liu h, liu d. J Chem Inf Model. 2011 Nov 28;51(11):2821-8. doi: 10.1021/ci200264h. Epub 2011 Oct 11. J Chem Inf Model. 2011. PMID: 21955088

2

Design, synthesis, and interaction study of quinazoline-2(1H)-thione derivatives as novel potential Bcl-xL inhibitors.

Feng Y, Ding X, Chen T, Chen L, Liu F, Jia X, Luo X, Shen X, Chen K, Jiang H, Wang H, Liu H, Liu D. Feng Y, et al. Among authors: liu h, liu f, liu d. J Med Chem. 2010 May 13;53(9):3465-79. doi: 10.1021/jm901004c. J Med Chem. 2010. PMID: 20405848

3

Inhibitor discovery targeting the intermediate structure of beta-amyloid peptide on the conformational transition pathway: implications in the aggregation mechanism of beta-amyloid peptide.

Liu D, Xu Y, Feng Y, Liu H, Shen X, Chen K, Ma J, Jiang H. Liu D, et al. Among authors: liu h. Biochemistry. 2006 Sep 12;45(36):10963-72. doi: 10.1021/bi060955f. Biochemistry. 2006. PMID: 16953582

4

Dual role of Zn2+ in maintaining structural integrity and suppressing deacetylase activity of SIRT1.

Chen L, Feng Y, Zhou Y, Zhu W, Shen X, Chen K, Jiang H, Liu D. Chen L, et al. Among authors: liu d. J Inorg Biochem. 2010 Feb;104(2):180-5. doi: 10.1016/j.jinorgbio.2009.10.021. Epub 2009 Oct 29. J Inorg Biochem. 2010. PMID: 19923004

5

Structural optimization and biological evaluation of substituted bisphenol A derivatives as beta-amyloid peptide aggregation inhibitors.

Zhou Y, Jiang C, Zhang Y, Liang Z, Liu W, Wang L, Luo C, Zhong T, Sun Y, Zhao L, Xie X, Jiang H, Zhou N, Liu D, Liu H. Zhou Y, et al. Among authors: liu h, liu w, liu d. J Med Chem. 2010 Aug 12;53(15):5449-66. doi: 10.1021/jm1000584. J Med Chem. 2010. PMID: 20684593

6

A new assay based on fluorescence resonance energy transfer to determine the binding affinity of Bcl-xL inhibitors.

Feng Y, Shen X, Chen K, Jiang H, Liu D. Feng Y, et al. Among authors: liu d. Biosci Biotechnol Biochem. 2008 Jul;72(7):1936-9. doi: 10.1271/bbb.70735. Epub 2008 Jul 7. Biosci Biotechnol Biochem. 2008. PMID: 18603801 Free article.

7

Identification of benzofuran-3-yl(phenyl)methanones as novel SIRT1 inhibitors: binding mode, inhibitory mechanism and biological action.

Wu J, Li Y, Chen K, Jiang H, Xu MH, Liu D. Wu J, et al. Among authors: liu d. Eur J Med Chem. 2013 Feb;60:441-50. doi: 10.1016/j.ejmech.2012.12.026. Epub 2012 Dec 20. Eur J Med Chem. 2013. PMID: 23318905

8

Structural optimization and biological evaluation of 1,5-disubstituted pyrazole-3-carboxamines as potent inhibitors of human 5-lipoxygenase.

Zhou Y, Liu J, Zheng M, Zheng S, Jiang C, Zhou X, Zhang D, Zhao J, Ye D, Zheng M, Jiang H, Liu D, Cheng J, Liu H. Zhou Y, et al. Among authors: liu j, liu h, liu d. Acta Pharm Sin B. 2016 Jan;6(1):32-45. doi: 10.1016/j.apsb.2015.11.004. Epub 2016 Jan 7. Acta Pharm Sin B. 2016. PMID: 26904397 Free PMC article.

9

Structure assembly of Bcl-x(L) through alpha5-alpha5 and alpha6-alpha6 interhelix interactions in lipid membranes.

Feng Y, Liu D, Shen X, Chen K, Jiang H. Feng Y, et al. Among authors: liu d. Biochim Biophys Acta. 2009 Nov;1788(11):2389-95. doi: 10.1016/j.bbamem.2009.09.006. Epub 2009 Sep 15. Biochim Biophys Acta. 2009. PMID: 19761754 Free article.

10

An enzyme-linked immunosorbent assay to compare the affinity of chemical compounds for β-amyloid peptide as a monomer.

Jiang C, Feng Y, Huang X, Xu Y, Zhang Y, Zhou N, Shen X, Chen K, Jiang H, Liu D. Jiang C, et al. Among authors: liu d. Anal Bioanal Chem. 2010 Mar;396(5):1745-54. doi: 10.1007/s00216-009-3420-6. Epub 2010 Feb 6. Anal Bioanal Chem. 2010. PMID: 20135308

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